Search Results - "Sardin, Elodie"

role for FKBP52 in Tau protein function by Chambraud, Béatrice, Sardin, Elodie, Giustiniani, Julien, Dounane, Omar, Schumacher, Michael, Goedert, Michel, Baulieu, Etienne-Emile

“…Tau is a microtubule-associated protein, which is widely expressed in the central nervous system, predominantly in neurons, where it regulates microtubule…”
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Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy by Giustiniani, Julien, Chambraud, Béatrice, Sardin, Elodie, Dounane, Omar, Guillemeau, Kevin, Nakatani, Hiroko, Paquet, Dominik, Kamah, Amina, Landrieu, Isabelle, Lippens, Guy, Baulieu, Etienne-Emile, Tawk, Marcel

“…The Tau protein is the major component of intracellular filaments observed in a number of neurodegenerative diseases known as tauopathies. The pathological…”
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Decreasing cytosolic translation is beneficial to yeast and human Tafazzin-deficient cells by de Taffin de Tilques, Maxence, Lasserre, Jean-Paul, Godard, François, Sardin, Elodie, Bouhier, Marine, Le Guedard, Marina, Kucharczyk, Roza, Petit, Patrice X, Testet, Eric, di Rago, Jean-Paul, Tribouillard-Tanvier, Déborah

“…Cardiolipin (CL) optimizes diverse mitochondrial processes, including oxidative phosphorylation (OXPHOS). To function properly, CL needs to be unsaturated,…”
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The FK506‐binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion‐like behavior by Giustiniani, Julien, Guillemeau, Kevin, Dounane, Omar, Sardin, Elodie, Huvent, Isabelle, Schmitt, Alain, Hamdane, Malika, Buée, Luc, Landrieu, Isabelle, Lippens, Guy, Baulieu, Etienne Emile, Chambraud, Béatrice

“…Tauopathies, including Alzheimer's disease (AD), are neurodegenerative diseases associated with the pathologic aggregation of human brain Tau protein. Neuronal…”
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Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome by Su, Xin, Rak, Malgorzata, Tetaud, Emmanuel, Godard, François, Sardin, Elodie, Bouhier, Marine, Gombeau, Kewin, Caetano-Anollés, Derek, Salin, Bénédicte, Chen, Huimei, di Rago, Jean-Paul, Tribouillard-Tanvier, Déborah

“…Abstract The m.8993T>G mutation of the mitochondrial MT-ATP6 gene has been associated with numerous cases of neuropathy, ataxia and retinitis pigmentosa and…”
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Decrease of the immunophilin FKBP52 accumulation in human brains of Alzheimer's disease and FTDP-17 by Giustiniani, Julien, Sineus, Marlène, Sardin, Elodie, Dounane, Omar, Panchal, Maï, Sazdovitch, Véronique, Duyckaerts, Charles, Chambraud, Béatrice, Baulieu, Etienne-Emile

“…Human neurodegenerative diseases characterized by abnormal intraneuronal inclusions of the tau protein, or "tauopathies", include Alzheimer's disease (AD),…”
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Biochemical investigation of a human pathogenic mutation in the nuclear ATP5E gene using yeast as a model by Sardin, Elodie, Donadello, Stéphanie, di Rago, Jean-Paul, Tetaud, Emmanuel

“…F1F0-ATP synthase is a key enzyme of the mitochondrial energetic metabolism responsible for the production of most cellular ATP in humans. Mayr et al. (2010)…”
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