Search Results - "Sarantakis, Dimitri"

Novel diaryl ureas with efficacy in a mouse model of malaria by Anderson, John W., Sarantakis, Dimitri, Terpinski, Jacek, Santha Kumar, T.R., Tsai, Han-Chun, Kuo, Mack, Ager, Arba L., Jacobs, William R., Schiehser, Guy A., Ekins, Sean, Sacchettini, James C., Jacobus, David P., Fidock, David A., Freundlich, Joel S.

“…Exploration of triclosan analogs has led to novel diaryl ureas with significant potency against in vitro cultures of drug-resistant and drug-sensitive strains…”
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Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives by Freundlich, Joel S., Anderson, John W., Sarantakis, Dimitri, Shieh, Hong-Ming, Yu, Min, Valderramos, Juan-Carlos, Lucumi, Edinson, Kuo, Mack, Jacobs, William R., Fidock, David A., Schiehser, Guy A., Jacobus, David P., Sacchettini, James C.

“…Nanomolar inhibitors of P. falciparum enoyl acyl carrier protein reductase are presented that demonstrate potent anti-parasitic efficacy. A structure-based…”
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Erratum to “Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives” [Bioorg. Med. Chem. Lett. 15 (2005) 5247–5252] by Freundlich, Joel S., Anderson, John W., Sarantakis, Dimitri, Shieh, Hong-Ming, Yu, Min, Valderramos, Juan-Carlos, Lucumi, Edinson, Kuo, Mack, Jacobs, William R., Fidock, David A., Schiehser, Guy A., Jacobus, David P., Sacchettini, James C.

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Corrigendum to “Synthesis, characterization, and evaluation of pro-drugs of VLA-4 antagonists” by Huryn, D.M., Ashwell, Susan, Baudy, Reinhardt, Dressen, Darren B., Gallaway, William, Grant, Francine S., Konradi, Andrei, Ley, Robert W., Petusky, Susan, Pleiss, Michael A., Sarantakis, Dimitri, Semko, Christopher M., Sherman, Mary M., Tio, Cesar, Zhang, Lu

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Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists by Huryn, Donna M, Ashwell, Susan, Baudy, Reinhardt, Dressen, Darren B, Gallaway, William, Grant, Francine S, Konradi, Andrei, Ley, Robert W, Petusky, Susan, Pleiss, Michael A, Sarantakis, Dimitri, Semko, Christopher M, Sherman, Mary M, Tio, Cesar, Zhang, Lu

“…A pro-drug strategy to identify orally efficacious VLA-4 antagonists is described. Potential pro-drugs were evaluated for their physical chemical…”
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Luteinising hormone-releasing and anti-fertility properties of a glucagon-selective somatostatin analogue by Bex, Frederick J, Corbin, Alan, Sarantakis, Dimitri, Lien, Eric

“…The hypothalamic tetradecapeptide, somatostatin (SRIF), inhibits the secretion of growth hormone (GH) and numerous other hormones, including insulin and…”
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Postcoital contraceptive effects of agonist analogs of luteinizing hormone-releasing hormone by Corbin, A, Beattie, C W, Rees, R, Yardley, J, Foell, T J, Chai, S Y, McGregor, H, Garsky, V, Sarantakis, D, McKinley, W A

“…Various analogs of synthetic hypothalamic luteinizing hormone-releasing hormone (LH-RH) were evaluated for agonistic (ovulation-inducing), postcoital…”
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