Search Results - "Sarangapani, R."

Gamma ray buildup factors for conventional shielding materials and buildup factors computed for tungsten with a thickness beyond 40 mean free paths by Basu, Pew, Sarangapani, R., Venkatraman, B.

“…In this study, gamma ray buildup factors were investigated for conventional shielding materials such as lead, iron, concrete, and tungsten based on standard…”
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Compact shielding design for 740 GBq 241Am-Be neutron source transport container by Basu, Pew, Sarangapani, R., Venkatraman, B.

“…For transport and storage of neutron sources, shielding materials like polymers and multi layer shields are used. A compact shielding design for 740 GBq…”
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Gamma spectrometry of coolant lines of KAMINI reactor by Srinivasan, T. K., Annadurai, P. M., Raghuraman, Akila, Sarangapani, R.

“…Gamma spectrometry of the KAMINI reactor coolant lines at the selected spots/locations was carried out during 20kWt power and shutdown using portable…”
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Estimation of activity concentrations of radioactive gases inside containment building of fast breeder reactor FBTR: Leakage of active cover gas by Mitra, Arya, Sarangapani, R., Chandrasekaran, S., Jose, M.T.

“…Leakage of active reactor vessel cover gas through liquid metal seal or various injection and rejection points of the reactor vessel cover gas system,…”
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Rheology studies of NTO–TNT based melt-cast dispersions and influence of particle–dispersant interactions by Sarangapani, R., Ramavat, V., Reddy, S., Subramanian, P., Sikder, A.K.

“…3-Nitro-1,2,4-triazol-5-one (NTO) is a promising candidate of insensitive munitions and it is currently explored to achieve shock insensitive melt-cast…”
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Computational fluid dynamics simulations of aqueous flow through the CyPass® Micro‐Stent by Vidal Aroca, F., Vera, L.F., Missel, P., Sarangapani, R.

“…Purpose In normotensive eyes, aqueous humor is eliminated through Schlemm's canal and through the iris root in approximately equal fractions. But in…”
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On the anticipation of the human dose in first-in-man trials from preclinical and prior clinical information in early drug development by Lowe, P. J., Hijazi, Y., Luttringer, O., Yin, H., Sarangapani, R., Howard, D.

“…The drug development process is divided into phases with decisions required on compound selection and promotion to each subsequent development phase. In…”
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Route-Specific Differences in Distribution Characteristics of Octamethylcyclotetrasiloxane in Rats: Analysis Using PBPK Models by Sarangapani, Ramesh, Teeguarden, Justin, Andersen, Melvin E., Reitz, Richard H., Plotzke, Kathleen P.

“…Octamethylcyclotetrasiloxane (D4) is used in selected consumer products and has a potential for human exposure from multiple routes. Here we develop a…”
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An improvement to the Kalos’ formula for double layer gamma ray exposure buildup factors for shielding materials of nuclear and radiological facilities by Basu, Pew, Sarangapani, R., Venkatraman, B.

“…•Double layer gamma ray exposure buildup factors (DBUFs) for concrete, iron, lead, and tungsten.•Comparative analysis of DBUFs using MCNP, ASFIT and empirical…”
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The Role of Dispersion in Particle Deposition in Human Airways by Sarangapani, Ramesh, Wexler, Anthony S.

“…Aerosol dispersion and deposition are processes that occur concurrently in human airways. However, dispersion has not been properly accounted for in most…”
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QADCGPIC–M: A point kernel shielding code with features for handling bulk shields up to 100 mean free path and stratified shielding configurations by Basu, Pew, Sarangapani, R., Venkatraman, B.

“…[Display omitted] •Provision to handle thick shields up to 100 mean free path.•Incorporation of modified Kalos’ formula for double layer gamma ray exposure…”
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GUI2QAD-3D: A graphical interface program for QAD-CGPIC program by Subbaiah, K.V., Sarangapani, R.

“…GUI2QAD-3D is graphical user interface developed in Visual Basic (VB) version 6.0 to prepare input for the QAD-CGPIC program. QAD-CGPIC is a FORTRAN code that…”
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Modeling Particle Deposition in Extrathoracic Airways by Sarangapani, Ramesh

“…The extrathoracic (ET) airways filter, warm, and humidify the inspired air and provide olfactory function. These multiple functions are reflected in its…”
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Dose-Response Modeling of Cytochrome P450 Induction in Rats by Octamethylcyclotetrasiloxane by Sarangapani, Ramesh, Teeguarden, Justin, Plotzke, Kathleen P., McKim, James M., Andersen, Melvin E.

“…Inhalation of octamethylcyclotetrasiloxane (D4) induces CYP2B1/2 protein and causes liver enlargement. We have developed a pharmacodynamic (PD) extension to a…”
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PHYSIOLOGICALLY BASED CLEARANCE/EXTRACTION MODELS FOR COMPOUNDS METABOLIZED IN THE NOSE: An Example with Methyl Methacrylate by Andersen, Melvin E., Sarangapani, Ramesh

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Regional distribution and kinetics of vinyl acetate hydrolysis in the oral cavity of the rat and mouse by Morris, John B, Symanowicz, Peter, Sarangapani, Ramesh

“…Vinyl acetate is an ester that is used to make polyvinyl acetate based polymers that are used in the manufacture of latex paints and adhesives. Chronic oral…”
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Measurement of dose rate profile and spectra through a cylindrical duct vis-à-vis Monte Carlo simulation studies for optimisation of reactor shield design by Sarangapani, R., Jose, M.T., Meenakshisundaram, V., Subbaiah, K.V.

“…In the design of a nuclear reactor, penetrations are provided in the top shield to carry out some essential operations. Radiation streaming is envisaged…”
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Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi) by Gu, Jessie, Noe, Adele, Chandra, Priya, Al-Fayoumi, Suliman, Ligueros-Saylan, Monica, Sarangapani, Ramesh, Maahs, Suzanne, Ksander, Gary, Rigel, Dean F., Jeng, Arco Y., Lin, Tsu-Han, Zheng, Weiyi, Dole, William P.

“…Angiotensin receptor blockade and neprilysin (NEP) inhibition together offer potential benefits for the treatment of hypertension and heart failure. LCZ696 is…”
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Growth and neutralization of sulfate aerosols in human airways by Sarangapani, R, Wexler, A S

“…Evidence derived from in vivo and in vitro laboratory experiments, controlled human exposure studies, and epidemiological studies on mortality and morbidity…”
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Particles do not increase vapor deposition in human airways by Wexler, A.S, Sarangapani, R

“…Highly water-soluble vapors deposit in the upper airways of the respiratory tract because they are rapidly absorbed by the mucus lining and therefore it has…”
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