Search Results - "Saraiva, R"

The Neanderthal inside us by Saraiva, Luis R.

“…Luis Saraiva recalls a 1997 paper by Krings et al., which reports the sequencing of mitochondrial Neanderthal DNA extracted from a 40,000-year-old bone,…”
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High-throughput spatial mapping of single-cell RNA-seq data to tissue of origin by Achim, Kaia, Pettit, Jean-Baptiste, Saraiva, Luis R, Gavriouchkina, Daria, Larsson, Tomas, Arendt, Detlev, Marioni, John C

“…Single cells profiled by RNA-seq are rapidly assigned to their location in a complextissue using data in gene expression atlases. Understanding cell type…”
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Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration by Ambrosi, Thomas H., Scialdone, Antonio, Graja, Antonia, Gohlke, Sabrina, Jank, Anne-Marie, Bocian, Carla, Woelk, Lena, Fan, Hua, Logan, Darren W., Schürmann, Annette, Saraiva, Luis R., Schulz, Tim J.

“…Aging and obesity induce ectopic adipocyte accumulation in bone marrow cavities. This process is thought to impair osteogenic and hematopoietic regeneration…”
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Computational assignment of cell-cycle stage from single-cell transcriptome data by Scialdone, Antonio, Natarajan, Kedar N., Saraiva, Luis R., Proserpio, Valentina, Teichmann, Sarah A., Stegle, Oliver, Marioni, John C., Buettner, Florian

“…•Machine learning based approaches allow cell cycle stage to be predicted from single-cell RNA-sequencing data.•Appropriate normalisation and use of prior…”
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Combinatorial effects of odorants on mouse behavior by Saraiva, Luis R., Kondoh, Kunio, Ye, Xiaolan, Yoon, Kyoung-hye, Hernandez, Marcus, Buck, Linda B.

“…The mechanisms by which odors induce instinctive behaviors are largely unknown. Odor detection in the mouse nose is mediated by >1, 000 different odorant…”
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A large-scale analysis of odor coding in the olfactory epithelium by Nara, Kiyomitsu, Saraiva, Luis R, Ye, Xiaolan, Buck, Linda B

“…Mammals can perceive and discriminate myriad volatile chemicals as having a distinct odor. Odorants are initially detected by odorant receptors (ORs) on…”
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The olfactory transcriptomes of mice by Ibarra-Soria, Ximena, Levitin, Maria O, Saraiva, Luis R, Logan, Darren W

“…The olfactory (OR) and vomeronasal receptor (VR) repertoires are collectively encoded by 1700 genes and pseudogenes in the mouse genome. Most OR and VR genes…”
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Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq by Saraiva, Luis R., Ibarra-Soria, Ximena, Khan, Mona, Omura, Masayo, Scialdone, Antonio, Mombaerts, Peter, Marioni, John C., Logan, Darren W.

“…The mouse olfactory mucosa is a complex chemosensory tissue composed of multiple cell types, neuronal and non-neuronal. We have here applied RNA-seq…”
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Early Childhood Predictors for Dental Caries: A Machine Learning Approach by Toledo Reyes, L., Knorst, J.K., Ortiz, F.R., Brondani, B., Emmanuelli, B., Saraiva Guedes, R., Mendes, F.M., Ardenghi, T.M.

“…We aimed to develop and validate caries prognosis models in primary and permanent teeth after 2 and 10 y of follow-up through a machine learning (ML) approach,…”
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Calcium Signaling Regulates Autophagy and Apoptosis by Sukumaran, Pramod, Nascimento Da Conceicao, Viviane, Sun, Yuyang, Ahamad, Naseem, Saraiva, Luis R, Selvaraj, Senthil, Singh, Brij B

“…Calcium (Ca2+) functions as a second messenger that is critical in regulating fundamental physiological functions such as cell growth/development, cell…”
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High-affinity olfactory receptor for the death-associated odor cadaverine by Hussain, Ashiq, Saraiva, Luis R., Ferrero, David M., Ahuja, Gaurav, Krishna, Venkatesh S., Liberles, Stephen D., Korsching, Sigrun I.

“…Carrion smell is strongly repugnant to humans and triggers distinct innate behaviors in many other species. This smell is mainly carried by two small aliphatic…”
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Odor coding in the mammalian olfactory epithelium by Kurian, Smija M., Naressi, Rafaella G., Manoel, Diogo, Barwich, Ann-Sophie, Malnic, Bettina, Saraiva, Luis R.

“…Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with…”
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Hepatobiliary and Pancreatic: An unusual cause of biliary obstruction by Saraiva, RO, Gamelas, V, Canha, MI, Carvalho, D, Loureiro, R, Coimbra, J

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From Akute Primäre Verruckheit to Bouffée Delirante: The background of Acute Transient Psychosis by Romão, J., Gonçalves, M., André, R., Félix, F., Saraiva, R., Abreu, M.

“…Introduction Ever since the end of the 19th century that descriptions of acute and transient psychosis (ATP) have been found in the literature. Psychiatrists…”
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Growing use of valproic acid in substance use disorders by Romão, J., Gonçalves, M., Ribeiro, M., André, R., Saraiva, R., Abreu, M.

“…Introduction Valproic acid is an antiepileptic drug used in different fields of Psychiatry. It is known mostly for its use in managing patients with bipolar…”
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Conserved genes regulating human sex differentiation, gametogenesis and fertilization by Fakhro, Khalid A, Awwad, Johnny, Garibova, Suma, Saraiva, Luis R, Avella, Matteo

“…The study of the functional genome in mice and humans has been instrumental for describing the conserved molecular mechanisms regulating human reproductive…”
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Nitrogen signalling in plant interactions with associative and endophytic diazotrophic bacteria by Carvalho, T. L. G., Balsemão-Pires, E., Saraiva, R. M., Ferreira, P. C. G., Hemerly, A. S.

“…Some beneficial plant-interacting bacteria can biologically fix N 2 to plant-available ammonium. Biological nitrogen fixation (BNF) is an important source of…”
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Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts by Hussain, Ashiq, Saraiva, Luis R, Korsching, Sigrun I

“…Trace amine-associated receptors (TAARs) in mammals recently have been shown to function as olfactory receptors. We have delineated the taar gene family in…”
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COVID-19 pandemic: Regarding alcohol consumption by Gonçalves, M.J., Linhares, L., Sereijo, C., Saraiva, R., Ismail, F.

“…Introduction On March, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a global pandemic. Social isolation, unemployment and financial…”
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The phenomenology of motivation by André, R., Romão, J., Azevedo, F., Gonçalves, M., Sereijo, C., Saraiva, R., Croca, M., Abreu, M.

“…Introduction The concept of motivation pervades our professional and personal lives. Motivation is almost impossible to be observed directly, it is a construct…”
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