Transfusion malaria control in both endemic and non endemic region of Brazil

The aim of the present work was to establish appropriate criteria for screening of donor blood from regions with distinct Malaria epidemiological characteristics. Three locations with different screening criteria were studied: São Paulo, SP (with no vectorial transmission), Belém, PA (with low activ...

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Bibliographic Details
Published in:	Revista da Sociedade Brasileira de Medicina Tropical Vol. 31; no. 1
Main Authors:	Sáez-Alquézar, Amadeo, Ramos, Ana Maria S, do, Val, Di, Santi Silvia M, Branquinho, Maria Stela, Kirchgatter, Karin, Cordeiro, Ingrid A, Murta, Marcia, Saraiva, João C, Oliveira, Salma Gomes de, Bochetti, Maria Gabriella Gioelli, Pirolla, José Antonio, Guerzoni, Dalton, Chamone, Dalton A
Format:	Journal Article
Language:	English
Published:	Rio de Janeiro Sociedade Brasileira de Medicina Tropical 01-01-1998
Subjects:	Blood Disease transmission Malaria Parasites Vector-borne diseases
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Summary:	The aim of the present work was to establish appropriate criteria for screening of donor blood from regions with distinct Malaria epidemiological characteristics. Three locations with different screening criteria were studied: São Paulo, SP (with no vectorial transmission), Belém, PA (with low active transmission) and Matupá and Peixoto de Azevedo, MT (with high active transmission). The Malaria parasite ¾ Plasmodium sp ¾ was searched for by "thick film", QBC Test( and antigen Immunofluorescence test, and was not detected in any of the samples. There was, however, a great variation in the positivity of anti-plasmodial antibodies, as determined by IIF-IgG anti-P. vivax and -P. falciparum, between accepted donors in the 3 studied locations and between rejected and accepted donors in São Paulo (1.98% accepted, 22.3% rejected - p < 0.01) and Belém (17.2% accepted, 58.3% rejected - p < 0.01). These data endorse the use of the applied clinical and epidemiological screening. In Matupá and Peixoto de Azevedo, where there was no rejected donor, the serological positivity was 80.6%. We, therefore, consider that the Malaria screening in blood banks should follow clinical and epidemiological criteria suitable to each region. The laboratorial screening techniques should then detect either the parasites (thick film/ QBC Test® or the parasite antigens.
ISSN:	0037-8682 1678-9849
DOI:	10.1590/S0037-86821998000100004