Search Results - "Saraiva, André Lopes"
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Antidiabetic potential of Bauhinia forficata Link leaves: a non-cytotoxic source of lipase and glycoside hydrolases inhibitors and molecules with antioxidant and antiglycation properties
Published in Biomedicine & pharmacotherapy (01-03-2020)“…[Display omitted] Bauhinia forficata Link., a cerrado native plant, is used as a complementary treatment for Type 2 Diabetes Mellitus (T2DM). Several studies…”
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Antioxidant compounds from Annona crassiflora fruit peel reduce lipid levels and oxidative damage and maintain the glutathione defense in hepatic tissue of Triton WR-1339-induced hyperlipidemic mice
Published in Biomedicine & pharmacotherapy (01-10-2021)“…Dyslipidemia is a risk factor for the pathogenesis of several diseases, such as obesity, hypertension, atherosclerosis and cardiovascular diseases. In addition…”
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What do we know about Toll-Like Receptors Involvement in Gout Arthritis?
Published in Endocrine, metabolic & immune disorders drug targets (01-01-2023)“…Toll-like receptors (TLRs) are a well-characterized family of cell-bound pattern recognition receptors able to identify and respond to conserved structures of…”
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Increased selenium concentration in the synthesis of CdSe magic‐sized quantum dots affects how the brain responds to oxidative stress
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-05-2022)“…CdSe magic‐sized quantum dots (MSQDs) have been widely used as fluorescent probes in biological systems due to their excellent optical properties with a…”
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Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury
Published in Pharmaceutics (31-05-2022)“…Annona muricata Linn. is a common plant found in the warmest regions of South and Central America and its use in traditional medicine has been reported for the…”
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Angiotensin type 2 receptor antagonism as a new target to manage gout
Published in Inflammopharmacology (01-12-2022)“…Background There is a growing search for therapeutic targets in the treatment of gout. The present study aimed to evaluate the analgesic and anti-inflammatory…”
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Creatine reduces oxidative stress markers but does not protect against seizure susceptibility after severe traumatic brain injury
Published in Brain research bulletin (10-02-2012)“…Highlights ► Traumatic brain injury (TBI) induces oxidative damage 4 and 8 days after injury. ► TBI induces Na+ ,K+ -ATPase inhibition, 4 and 8 days after…”
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N-Acetylcysteine prevents baker’s-yeast-induced inflammation and fever
Published in Inflammation research (01-02-2012)“…Objetive and design To investigate whether N -acetylcysteine (NAC) alters baker’s-yeast-induced fever and inflammation. Material or subjects Male Wistar rats…”
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Antidiabetic effects of Syzygium cumini leaves: A non-hemolytic plant with potential against process of oxidation, glycation, inflammation and digestive enzymes catalysis
Published in Journal of ethnopharmacology (28-10-2020)“…Plant materials are commonly used in traditional medicine in order to treat various diseases such as Diabetes mellitus. Some plants, such as Syzygium cumini,…”
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Flavonoids and proanthocyanidins-rich fractions from Eugenia dysenterica fruits and leaves inhibit the formation of advanced glycation end-products and the activities of α-amylase and α-glucosidase
Published in Journal of ethnopharmacology (01-03-2022)“…Different parts of Eugenia dysenterica have been popularly used in Brazil for treating diabetes mellitus and its complications. The present study aimed to…”
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Phytochemical composition of aerial parts and roots of Pfaffia glomerata (Spreng.) Pedersen and anticholinesterase, antioxidant, and antiglycation activities
Published in Protoplasma (01-07-2024)“…The Pfaffia glomerata , a plant popularly called Brazilian ginseng, is widely used in Brazil for the treatment of various pathologies, including those…”
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A 20-hydroxyecdysone-enriched fraction from Pfaffia glomerata (Spreng.) pedersen roots alleviates stress, anxiety, and depression in mice
Published in Journal of ethnopharmacology (01-03-2021)“…Pfaffia glomerata roots are widely used in Brazil to treat various pathological conditions, particularly psychological disorders. 20-hydroxyecdysone, a…”
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Diacerein decreases TNF-α and IL-1β levels in peritoneal fluid and prevents Baker's yeast-induced fever in young rats
Published in Inflammation research (01-03-2010)“…Objective To investigate the effect of diacerein, an anti-inflammatory drug, on body temperature and protocols of fever induction in male Wistar rats. Methods…”
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CdSe magic-sized quantum dots attenuate reactive oxygen species generated by neutrophils and macrophages with implications in experimental arthritis
Published in Nanomedicine (01-06-2022)“…The biological applicability of nanomaterials has been limited due to cytotoxicity. Studies have described the effects of nanomaterials on different tissues…”
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Biochemical characterization and assessment of leishmanicidal effects of a new L-amino acid oxidase from Crotalus durissus collilineatus snake venom (CollinLA AO-I)
Published in Toxicon (Oxford) (01-07-2023)“…This study reports the isolation of CollinLAAO-I, a new L-amino acid oxidase from Crotalus durissus collilineatus snake venom, its biochemical characterization…”
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Citrullinated human fibrinogen triggers arthritis through an inflammatory response mediated by IL-23/IL-17 immune axis
Published in International immunopharmacology (01-12-2021)“…•Immunization with citrullinated human fibrinogen induces ACPA antibody production.•Joint injection of human fibrinogen causes arthritis in previously…”
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Antioxidant compounds of Kielmeyera coriacea Mart. with α-amylase, lipase and advanced glycation end-product inhibitory activities
Published in Journal of pharmaceutical and biomedical analysis (30-11-2021)“…•LC-ESI-MS/MS analysis identified various proanthocyanidins in K. coriacea inner bark.•Liquid fractionation increased polyphenols in the polar…”
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Stephalagine, an aporphine alkaloid from Annona crassiflora fruit peel, induces antinociceptive effects by TRPA1 and TRPV1 channels modulation in mice
Published in Bioorganic chemistry (01-03-2020)“…[Display omitted] •A. crassiflora fruit peel extracts reduced formalin-induced nociception.•Stephalagine from A. crassiflora fruit peel reduced nociception and…”
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Anacardium humile St. Hil as a novel source of antioxidant, antiglycation and α-amylase inhibitors molecules with potential for management of oxidative stress and diabetes
Published in Journal of ethnopharmacology (25-03-2021)“…The substantial increase in diabetes cases worldwide has been a major public health problem, and the use of medicinal plants can be considered an interesting…”
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Protective effects of a polyphenol-enriched fraction of the fruit peel of Annona crassiflora Mart. on acute and persistent inflammatory pain
Published in Inflammopharmacology (01-06-2020)“…Different parts of Annona crassiflora Mart., a native species from Brazilian savanna, were traditionally used for the treatment of a wide variety of ailments…”
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