Search Results - "Sarah Siner"
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Clinical utility and acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): A prospective e-survey of parents and health professionals
Published in PloS one (15-09-2022)“…Background Paediatric early warning systems (PEWS) are a means of tracking physiological state and alerting healthcare professionals about signs of…”
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Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy
Published in PloS one (29-10-2020)“…Acute kidney injury (AKI), a common complication in paediatric intensive care units (PICU), is associated with increased morbidity and mortality. In this…”
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Clinical utility and acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): A prospective e-survey of parents and health professionals
Published in PloS one (15-09-2022)“…Background Paediatric early warning systems (PEWS) are a means of tracking physiological state and alerting healthcare professionals about signs of…”
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The economic burden experienced by carers of children who had a critical deterioration at a tertiary children’s hospital in the United Kingdom (the DETECT study): an online survey
Published in BMC pediatrics (31-08-2023)“…Abstract Background Unplanned critical care admissions following in-hospital deterioration in children are expected to impose a significant burden for carers…”
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Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom
Published in BMC health services research (04-07-2023)“…Electronic early warning systems have been used in adults for many years to prevent critical deterioration events (CDEs). However, implementation of similar…”
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Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children
Published in PloS one (05-02-2021)“…Bacterial Infections remains a leading cause of death in the Paediatric Intensive Care Unit (PICU). In this era of rising antimicrobial resistance, new tools…”
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Health professionals’ initial experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): a qualitative interview study
Published in BMC pediatrics (24-06-2022)“…Abstract Background Paediatric early warning systems (PEWS) alert health professionals to signs of a child’s deterioration with the intention of triggering an…”
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Parents’ experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): A qualitative interview study
Published in Frontiers in pediatrics (30-08-2022)“…Background Failure to recognize and respond to clinical deterioration in a timely and effective manner is an urgent safety concern, driving the need for early…”
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6471 Performance of eight different severity scores to predict critical care admission in paediatric inpatients treated for sepsis: a retrospective cohort study
Published in Archives of disease in childhood (01-08-2024)“…ObjectivesSepsis is a leading cause of deterioration leading to unplanned transfer to critical care (UTCC) in hospitalised children, but there are few…”
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Clinical utility and acceptability of a whole-hospital, pro-active electronic paediatric early warning system
Published in PloS one (15-09-2022)“…Background Paediatric early warning systems (PEWS) are a means of tracking physiological state and alerting healthcare professionals about signs of…”
Get full text
Journal Article -
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Title NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection
Published in Scientific reports (19-11-2020)“…Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation…”
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Procalcitonin and Other Common Biomarkers Do Not Reliably Identify Patients at Risk for Bacterial Infection After Congenital Heart Surgery
Published in Pediatric critical care medicine (01-03-2019)“…Following surgery, it is difficult to distinguish a postoperative inflammatory reaction from infection. This study examined the predictive value of the…”
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NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection
Published in Scientific reports (19-11-2020)“…Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation…”
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Seizure control via pH manipulation: a phase II double-blind randomised controlled trial of inhaled carbogen as adjunctive treatment of paediatric convulsive status epilepticus (Carbogen for Status Epilepticus in Children Trial (CRESCENT))
Published in Current controlled trials in cardiovascular medicine (29-05-2024)“…Paediatric convulsive status epilepticus is the most common neurological emergency presenting to emergency departments. Risks of resultant neurological…”
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The prognostic ability of early Braden Q Scores in critically ill children
Published in Nursing in critical care (01-03-2014)“…Background Pressure ulcer (PU) risk assessment tools are an important component of good nursing care; however, it is essential that these tools offer a good…”
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Observational infant exploratory [14C]‐paracetamol pharmacokinetic microdose/therapeutic dose study with accelerator mass spectrometry bioanalysis
Published in British journal of clinical pharmacology (01-07-2015)“…Aims The aims of the study were to compare [14C]‐paracetamol ([14C]‐PARA) paediatric pharmacokinetics (PK) after administration mixed in a therapeutic dose or…”
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