Search Results - "Sarah M. Wade"

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B by Wade, Sarah M., Trenkmann, Michelle, McGarry, Trudy, Canavan, Mary, Marzaioli, Viviana, Wade, Siobhan C., Veale, Douglas J., Fearon, Ursula

“…To investigate the functional role of miR-23a in synovial fibroblasts (SFC) activation in psoriatic arthritis (PsA). Differential expression of the…”
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Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis by Canavan, Mary, Walsh, Alice M, Bhargava, Vipul, Wade, Sarah M, McGarry, Trudy, Marzaioli, Viviana, Moran, Barry, Biniecka, Monika, Convery, Hannah, Wade, Siobhan, Orr, Carl, Mullan, Ronan, Fletcher, Jean M, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula

“…CD141+ DC are implicated in antiviral and antitumor immunity. However, mechanistic studies in autoimmune disease are limited. This is the first study to our…”
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Serum MicroRNA Signature as a Diagnostic and Therapeutic Marker in Patients with Psoriatic Arthritis by Wade, Sarah M, McGarry, Trudy, Wade, Siobhan C, Fearon, Ursula, Veale, Douglas J

“…MicroRNA (miRNA) are small endogenous regulatory RNA molecules that have emerged as potential therapeutic targets and biomarkers in autoimmunity. Here, we…”
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Response to: 'Polyfunctional TEM cells in psoriatic arthritis synovium skewed towards Th17 cells' by Raychaudhuri et al by Canavan, Mary, Wade, Sarah M, Veale, Douglas J, Fearon, Ursula

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Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis by Wade, Sarah M, Canavan, Mary, McGarry, Trudy, Low, Candice, Wade, Siobhan C, Mullan, Ronan H, Veale, Douglas J, Fearon, Ursula

“…This study examines polyfunctional T-cells in psoriatic arthritis (PsA) synovial tissue and their associations with clinical disease and implications for…”
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Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis by Conway, Richard, O'Neill, Lorraine, McCarthy, Geraldine M, Murphy, Conor C, Fabre, Aurelie, Kennedy, Susan, Veale, Douglas J, Wade, Sarah M, Fearon, Ursula, Molloy, Eamonn S

“…The pathogenesis of giant cell arteritis (GCA) remains unclear. T 1 and T 17 pathways are implicated, but the proximal initiators and effector cytokines are…”
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Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis by Wade, Sarah M., Ohnesorge, Nils, McLoughlin, Hayley, Biniecka, Monika, Carter, Steven P., Trenkman, Michelle, Cunningham, Clare C., McGarry, Trudy, Canavan, Mary, Kennedy, Breandán N., Veale, Douglas J., Fearon, Ursula

“…Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents targeting the…”
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Dysregulated miR-125a promotes angiogenesis through enhanced glycolysisResearch in context by Sarah M. Wade, Nils Ohnesorge, Hayley McLoughlin, Monika Biniecka, Steven P. Carter, Michelle Trenkman, Clare C. Cunningham, Trudy McGarry, Mary Canavan, Breandán N. Kennedy, Douglas J. Veale, Ursula Fearon

“…Background: Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents…”
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