Search Results - "Sarah D’Alessandro"

Human Endogenous Retroviruses Long Terminal Repeat Methylation, Transcription, and Protein Expression in Human Colon Cancer by Dolci, Maria, Favero, Chiara, Toumi, Wafa, Favi, Evaldo, Tarantini, Letizia, Signorini, Lucia, Basile, Giuseppe, Bollati, Valentina, D'Alessandro, Sarah, Bagnoli, Pietro, Ferrante, Pasquale, Delbue, Serena

“…Colon cancer is the fourth most common malignancy in both incidence and mortality in developed countries. Infectious agents are among the risk factors for…”
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Determination of the UV Inactivation Constant Under 280 nm UV LED Irradiation for SARS‐CoV‐2 by Biffi, Silvia, Signorini, Lucia, Cattaneo, Luciano, Della Corna, Lorenzo, Guercilena, Andrea, D’Alessandro, Sarah, Ferrante, Pasquale, Delbue, Serena

“…ABSTRACT The ongoing emergency provoked by the SARS‐CoV‐2 pandemic demands the development of technologies to mitigate the spread of infection, and UV…”
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The Use of Antimalarial Drugs against Viral Infection by D'Alessandro, Sarah, Scaccabarozzi, Diletta, Signorini, Lucia, Perego, Federica, Ilboudo, Denise P, Ferrante, Pasquale, Delbue, Serena

“…In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular,…”
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Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion by Paone, Silvio, D’Alessandro, Sarah, Parapini, Silvia, Celani, Francesco, Tirelli, Valentina, Pourshaban, Manoochehr, Olivieri, Anna

“…Malaria is still a devastating disease with 228 million cases globally and 405,000 lethal outcomes in 2018, mainly in children under five years of age. The…”
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Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story by D'Alessandro, Sarah, Menegola, Elena, Parapini, Silvia, Taramelli, Donatella, Basilico, Nicoletta

“…Artemisinin combination therapy (ACT) is recommended by the World Health Organization (WHO) as first line treatment for uncomplicated malaria both in adults…”
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Effect of Hypoxia on Gene Expression in Cell Populations Involved in Wound Healing by Basilico, Nicoletta, Prato, Mauro, Sangiovanni, Enrico, Fumagalli, Marco, Perego, Federica, Magnavacca, Andrea, D’Alessandro, Sarah, Dell'Agli, Mario

“…Wound healing is a complex process regulated by multiple signals and consisting of several phases known as haemostasis, inflammation, proliferation, and…”
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In Vitro Antimalarial Activity of Inhibitors of the Human GTPase Rac1 by Parapini, Silvia, Paone, Silvio, Erba, Emanuela, Cavicchini, Loredana, Pourshaban, Manoochehr, Celani, Francesco, Contini, Alessandro, D'Alessandro, Sarah, Olivieri, Anna

“…Malaria accounts for millions of cases and thousands of deaths every year. In the absence of an effective vaccine, drugs are still the most important tool in…”
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Oxidative Inactivation of SARS-CoV-2 on Photoactive AgNPs@TiO2 Ceramic Tiles by Djellabi, Ridha, Basilico, Nicoletta, Delbue, Serena, D’Alessandro, Sarah, Parapini, Silvia, Cerrato, Giuseppina, Laurenti, Enzo, Falletta, Ermelinda, Bianchi, Claudia

“…The current SARS-CoV-2 pandemic causes serious public health, social, and economic issues all over the globe. Surface transmission has been claimed as a…”
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Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity by Pozzetti, Luca, Ibba, Roberta, Rossi, Sara, Taglialatela-Scafati, Orazio, Taramelli, Donatella, Basilico, Nicoletta, D'Alessandro, Sarah, Parapini, Silvia, Butini, Stefania, Campiani, Giuseppe, Gemma, Sandra

“…The potential of natural and synthetic chalcones as therapeutic leads against different pathological conditions has been investigated for several years, and…”
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Screening of Mpro Protease (SARS-CoV-2) Covalent Inhibitors from an Anthocyanin-Rich Blueberry Extract Using an HRMS-Based Analytical Platform by Altomare, Alessandra, Baron, Giovanna, Cambiaghi, Giulia, Ferrario, Giulio, Zoanni, Beatrice, Larissa Della Vedova, Fumagalli, Giulio Maria, Sarah D’Alessandro, Parapini, Silvia, Vittorio, Serena, Vistoli, Giulio, Riso, Patrizia, Carini, Marina, Delbue, Serena, Aldini, Giancarlo

“…Background: The viral main protease (Mpro) of SARS-CoV-2 has been recently proposed as a key target to inhibit virus replication in the host. Therefore,…”
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Heat-Treated Lysozyme Hydrochloride: A Study on Its Structural Modifications and Anti-SARS-CoV-2 Activity by Delbue, Serena, Pariani, Elena, Parapini, Silvia, Galli, Cristina, Basilico, Nicoletta, D'Alessandro, Sarah, Pellegrino, Sara, Pini, Elena, Ciceri, Samuele, Ferraboschi, Patrizia, Grisenti, Paride

“…Lysozyme (E.C. 3.2.1.17), an about 14 kDa protein and pI 11, widely spread in nature, is present in humans mainly in milk, saliva, and intestinal mucus as a…”
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In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release by Dolci, Maria, Signorini, Lucia, D'Alessandro, Sarah, Perego, Federica, Parapini, Silvia, Sommariva, Michele, Taramelli, Donatella, Ferrante, Pasquale, Basilico, Nicoletta, Delbue, Serena

“…In the novel pandemic of Coronavirus Disease 2019, high levels of pro-inflammatory cytokines lead to endothelial activation and dysfunction, promoting a…”
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Multiplex array analysis of circulating cytokines and chemokines in COVID-19 patients during the first wave of the SARS-CoV-2 pandemic in Milan, Italy by Calvo-Alvarez, Estefanía, D'Alessandro, Sarah, Zanotta, Nunzia, Basilico, Nicoletta, Parapini, Silvia, Signorini, Lucia, Perego, Federica, Maina, Kevin Kamau, Ferrante, Pasquale, Modenese, Annalisa, Pizzocri, Pierluigi, Ronsivalle, Andrea, Delbue, Serena, Comar, Manola

“…The systemic inflammatory syndrome called "cytokine storm" has been described in COVID-19 pathogenesis, contributing to disease severity. The analysis of…”
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Serological follow-up of SARS-CoV-2 asymptomatic subjects by Milani, Gregorio Paolo, Dioni, Laura, Favero, Chiara, Cantone, Laura, Macchi, Chiara, Delbue, Serena, Bonzini, Matteo, Montomoli, Emanuele, Bollati, Valentina

“…SARS-CoV-2 symptoms are non-specific and can range from asymptomatic presentation to severe pneumonia. Asymptomatic subjects carrying SARS-CoV-2 often remain…”
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A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis by De Souza Pereira, Caroline, Quadros, Helenita Costa, Aboagye, Samuel Yaw, Fontinha, Diana, D?Alessandro, Sarah, Byrne, Margaret Elizabeth, Gendrot, Mathieu, Fonta, Isabelle, Mosnier, Joel, Moreira, Diogo Rodrigo M, Basilico, Nicoletta, Williams, David L, Prudêncio, Miguel, Pradines, Bruno, Navarro, Maribel

“…Hybrid-based drugs linked through a transition metal constitute an emerging concept for Plasmodium intervention. To advance the drug design concept and enhance…”
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Phagocytosis and activation of bone marrow-derived macrophages by Plasmodium falciparum gametocytes by Corbett, Yolanda, Parapini, Silvia, Perego, Federica, Messina, Valeria, Delbue, Serena, Misiano, Paola, Falchi, Mario, Silvestrini, Francesco, Taramelli, Donatella, Basilico, Nicoletta, D'Alessandro, Sarah

“…The innate immune response against various life cycle stages of the malaria parasite plays an important role in protection against the disease and regulation…”
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Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages by Coertzen, Dina, Reader, Janette, van der Watt, Mariëtte, Nondaba, Sindisiwe H, Gibhard, Liezl, Wiesner, Lubbe, Smith, Peter, D'Alessandro, Sarah, Taramelli, Donatella, Wong, Ho Ning, du Preez, Jan L, Wu, Ronald Wai Keung, Birkholtz, Lyn-Marie, Haynes, Richard K

“…The emergence of resistance toward artemisinin combination therapies (ACTs) by the malaria parasite has the potential to severely compromise malaria control…”
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Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle by Finaurini, Sara, Basilico, Nicoletta, Corbett, Yolanda, D’Alessandro, Sarah, Parapini, Silvia, Olliaro, Piero, Haynes, Richard K, Taramelli, Donatella

“…Abstract Artemisinin derivatives such as dihydroartemisinin (DHA) induce significant depletion of early embryonic erythroblasts in animal models. We have…”
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Isolation of SARS-CoV-2 strains carrying a nucleotide mutation, leading to a stop codon in the ORF 6 protein by Delbue, Serena, D'Alessandro, Sarah, Signorini, Lucia, Dolci, Maria, Pariani, Elena, Bianchi, Michele, Fattori, Stefania, Modenese, Annalisa, Galli, Cristina, Eberini, Ivano, Ferrante, Pasquale

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was isolated from the oro/pharyngeal swabs of two Italian COVID-19 patients, physicians in a…”
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Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle by Quadros, Helenita C., Çapcı, Aysun, Herrmann, Lars, D’Alessandro, Sarah, Fontinha, Diana, Azevedo, Raquel, Villarreal, Wilmer, Basilico, Nicoletta, Prudêncio, Miguel, Tsogoeva, Svetlana B., Moreira, Diogo R. M.

“…A recently developed artemisinin-quinoline hybrid, named 163A, has been shown to display potent activity against the asexual blood stage of Plasmodium, the…”
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