Search Results - "Saraco, Nora"

Estrogens in Human Male Gonadotropin Secretion and Testicular Physiology From Infancy to Late Puberty by Guercio, Gabriela, Saraco, Nora, Costanzo, Mariana, Marino, Roxana, Ramirez, Pablo, Berensztein, Esperanza, Rivarola, Marco A, Belgorosky, Alicia

“…Several reports in humans as well as transgenic mouse models have shown that estrogens play an important role in male reproduction and fertility. Estrogen…”
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Five New Cases of 46,XX Aromatase Deficiency: Clinical Follow-Up From Birth to Puberty, a Novel Mutation, and a Founder Effect by Marino, Roxana, Perez Garrido, Natalia, Costanzo, Mariana, Guercio, Gabriela, Juanes, Matías, Rocco, Carlos, Ramirez, Pablo, Warman, Diana M, Ciaccio, Marta, Pena, Gladys, Feyling, José García, Miras, Mirta, Rivarola, Marco A, Belgorosky, Alicia, Saraco, Nora

“…Context: Aromatase is the key enzyme for estrogen biosynthesis and is encoded by the CYP19A1 gene. Since 1991, several molecular CYP19A1 gene alterations…”
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VIP Promotes Recruitment of Tregs to the Uterine-Placental Interface During the Peri-Implantation Period to Sustain a Tolerogenic Microenvironment by Gallino, Lucila, Hauk, Vanesa, Fernández, Laura, Soczewski, Elizabeth, Gori, Soledad, Grasso, Esteban, Calo, Guillermina, Saraco, Nora, Berensztein, Esperanza, Waschek, James A, Pérez Leirós, Claudia, Ramhorst, Rosanna

“…Uterine receptivity and embryo implantation are two main processes that need a finely regulated balance between pro-inflammatory and tolerogenic mediators to…”
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Expression of aromatase, estrogen receptor α and β, androgen receptor, and cytochrome P-450scc in the human early prepubertal testis by BERENSZTEIN, Esperanza B, BAQUEDANO, Maria Sonia, GONZALEZ, Candela R, SARACO, Nora I, RODRIGUEZ, Jorge, PONZIO, Roberto, RIVAROLA, Marco A, BELGOROSKY, Alicia

“…The expression of aromatase, estrogen receptor alpha (ERalpha) and beta (ERbeta), androgen receptor (AR), and cytochrome P-450 side chain cleavage enzyme…”
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Accelerated Pubertal Tempo in a 46,XY Aromatase-Deficient Patient by Costanzo, Mariana, Garcia-Feyling, José, Saraco, Nora, Marino, Roxana, Pérez Garrido, Natalia, Touzon, Maria Sol, Viterbo, Gisela, Lazzati, Juan Manuel, Patiño, Hellem Carolina, Mattone, Celeste, Maceiras, Mercedes, Belgorosky, Alicia, Guercio, Gabriela

“…Aromatase deficiency is a rare autosomal recessive disorder. 46,XY-affected patients often remain undiagnosed until late puberty. Only 2 pediatric cases have…”
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Hypothalamic-Pituitary-Ovarian Axis during Infancy, Early and Late Prepuberty in an Aromatase-Deficient Girl Who Is a Compound Heterocygote for Two New Point Mutations of the CYP19 Gene by Belgorosky, Alicia, Pepe, Carolina, Marino, Roxana, Guercio, Gabriela, Saraco, Nora, Vaiani, Elisa, Rivarola, Marco A.

“…A loss of function mutation of the CYP19 aromatase gene leads to excess circulating androgens in the fetus and in the mother, resulting in ambiguous genitalia…”
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Metformin, estrogen replacement therapy and gonadotropin inhibition fail to improve insulin sensitivity in a girl with aromatase deficiency by Guercio, Gabriela, Di Palma, Maria Isabel, Pepe, Carolina, Saraco, Nora I, Prieto, Mariana, Saure, Carola, Mazza, Carmen, Rivarola, Marco A, Belgorosky, Alicia

“…Insulin resistance (IR), abnormal lipid profile, and other features of the metabolic syndrome have been described in CYP19 gene knockout mice and in…”
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Role of IGFs and Insulin in the Human Testis During Postnatal Activation: Differentiation of Steroidogenic Cells by Berensztein, Esperanza B, Baquedano, María S, Pepe, Carolina M, Costanzo, Mariana, Saraco, Nora I, Ponzio, Roberto, Rivarola, Marco A, Belgorosky, Alicia

“…Immunoexpression of IGF-I, IGF-II, type 1 IGF receptor (IGFR), insulin receptor (IR), and GH receptor (GHR) was analyzed in human testis, in three age groups…”
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The cytochrome P450 aromatase lacking exon 5 is associated with a phenotype of nonclassic aromatase deficiency and is also present in normal human steroidogenic tissues by Pepe, Carolina M., Saraco, Nora I., Baquedano, Maria Sonia, Guercio, Gabriela, Vaiani, Elisa, Marino, Roxana, Pandey, Amit V., Flück, Christa E., Rivarola, Marco A., Belgorosky, Alicia

“…Summary Objective   The previously described c655G>A mutation of the human cytochrome P450 aromatase gene (P450aro, CYP19) results in aberrant splicing due to…”
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Expression of the IGF system in human adrenal tissues from early infancy to late puberty : Implications for the development of adrenarche by BAQUEDANO, Maria Sonia, BERENSZTEIN, Esperanza, SARACO, Nora, DORN, Gabriela Vanesa, DE DAVILA, Maria T, RIVAROLA, Marco A, BELGOROSKY, Alicia

“…IGF-1, IGF-2, and type 1 IGF receptor (IGF-R1) mRNA expression and immunolocalization and cell proliferation index were studied in human adrenals from early…”
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Endocannabinoid signaling impairs syncytialization: Using flow cytometry to evaluate forskolin-induced cell fusion by Etcheverry, Tomás, Accialini, Paula, Palligas, Marcos, Loureiro, Florencia, Saraco, Nora, Martínez, Nora, Farina, Mariana

“…Cytotrophoblast cells fuse to form the syncytiotrophoblast, the main structure responsible for the placenta's specialized functions. This complex process…”
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HYPOXIA INDUCIBLE FACTOR-1 ALPHA IMPAIRS SYNCYTIALIZATION OF HUMAN TROPHOBLAST BEWO CELLS: ROLE OF ENDOCANNABINOID SYSTEM by Etcheverry, Tomás, Accialini, Paula, Palligas, Marcos, Abán, Cyntia, Saraco, Nora, Martínez, Nora, Farina, Mariana

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Exon 5 alternative splicing of the cytochrome P450 aromatase could be a regulatory mechanism for estrogen production in humans by Pepe, Carolina M, Saraco, Nora I, Baquedano, María Sonia, Guercio, Gabriela, Vaiani, Elisa, Berensztein, Esperanza, Rivarola, Marco A, Belgorosky, Alicia

“…P450 aromatase (P450Aro), involved in androgen to estrogen conversion, is encoded by the CYP19 gene. P450Aro c655G>A mutation described in heterozygous form in…”
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12279 Molecular Strategy And Genetic Characterization Of A Large Cohort Of Pediatric Patients With Hereditary Hypophosphatemic Rickets: Advantages Of Next Generation Sequencing by Garrido, Natalia Perez, Ramirez, Pablo, Viterbo, Gisela Lorena, del Pino, Mariana, Abbate, Silvina, Saraco, Nora Isabel, Tesan, Fiorella, Ciaccio, Marta, Fano, Virginia, Belgorosky, Alicia, Marino, Roxana

“…Abstract Disclosure: N. Perez Garrido: None. P. Ramirez: None. G.L. Viterbo: None. M. del Pino: None. S. Abbate: None. N.I. Saraco: None. F. Tesan: None. M…”
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Homeostasis loss in VIP deficient mice is associated with altered regulatory T cells recruitment by Gallino, Lucila, Hauk, Vanesa, Grasso, Esteban, Palligas, Marcos, Saraco, Nora, Berensztein, Esperanza, Pascuali, Natalia, Parborell, Fernanda, Waschek, James, Leirós, Claudia Perez, Ramhorst, Rosanna

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THU157 Epigenetic Regulation Of Genes Involved In The Signaling Cascade Of The GH Axis - IGF1 And Insulin. Implication In Children Postnatal Growth by Zoff, Luciana, Garcia, Francisco, Aschettino, Giovanna, Veneruzzo, Gabriel, Mattone, María Celeste, Garrido, Natalia Perez, Juanes, Matías, Saraco, Nora Isabel, Alonso, Cristina, Alonso, Cristina, Guercio, Gabriela, Belgorosky, Alicia, Baquedano, Maria Sonia

“…Abstract Disclosure: L. Zoff: None. F. Garcia: None. G. Aschettino: None. G. Veneruzzo: None. M.C. Mattone: None. N. Perez Garrido: None. M. Juanes: None. N.I…”
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DNA methylation is not involved in specific down-regulation of HSD3B2, NR4A1 and RARB genes in androgen-secreting cells of human adrenal cortex by Baquedano, María Sonia, Perez Garrido, Natalia, Goñi, Javier, Saraco, Nora, Aliberti, Paula, Berensztein, Esperanza, Rivarola, Marco A., Belgorosky, Alicia

“…We hypothesized that DNA methylation is involved in human adrenal functional zonation. mRNAs expression and methylation pattern of RARB, NR4A1 and HSD3B2 genes…”
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SUN-210 Differentially Expressed Mirnas in Zona Reticularis (ZR) Cells of the Human Adrenal Cortex by Garcia, Francisco, Colman, Diego, Zoff, Luciana, Saraco, Nora Isabel, Belgorosky, Alicia, Baquedano, Maria Sonia

“…Abstract The human adrenal cortex, involved in adaptive responses to stress, fluid homeostasis, and secondary sexual characteristics, arises from a tightly…”
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SAT-202 ERRγ1 Might Regulate Aromatase mRNA Variant Expression in Human Placental Tissues from Term Deliveries of Large for Gestational Age (LGA) Newborns Deliveries by Palligas, Marcos, Nemer, Cristina, Cannizzaro, Claudia, Baquedano, Maria, Belgorosky, Alicia, Saraco, Nora

“…Estrogens play important role in the placenta throughout the gestation. Human placenta (PL) expresses high levels of ERRγ type 1 isoform as well as Aromatase…”
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An Intron 9 CYP19 Gene Variant (IVS9+5G>A), Present in an Aromatase-Deficient Girl, Affects Normal Splicing and Is Also Present in Normal Human Steroidogenic Tissues by Saraco, Nora, Nesi-Franca, Suzana, Sainz, Romina, Marino, Roxana, Marques-Pereira, Rosana, La Pastina, Julia, Perez Garrido, Natalia, Sandrini, Romolo, Rivarola, Marco Aurelio, de Lacerda, Luiz, Belgorosky, Alicia

“…Splicing CYP19 gene variants causing aromatase deficiency in 46,XX disorder of sexual development (DSD) patients have been reported in a few cases. A…”
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