Search Results - "Sarac, Omer Sinan"
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Large‐scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants
Published in Proteins, structure, function, and bioinformatics (01-02-2018)“…Recent advances in computing power and machine learning empower functional annotation of protein sequences and their transcript variations. Here, we present an…”
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Journal Article -
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Proteomic profiling of HBV infected liver biopsies with different fibrotic stages
Published in Proteome science (20-04-2017)“…Hepatitis B virus (HBV) is a global health problem, and infected patients if left untreated may develop cirrhosis and eventually hepatocellular carcinoma. This…”
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GOPred: GO molecular function prediction by combined classifiers
Published in PloS one (31-08-2010)“…Functional protein annotation is an important matter for in vivo and in silico biology. Several computational methods have been proposed that make use of a…”
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Topology of functional networks predicts physical binding of proteins
Published in Bioinformatics (15-08-2012)“…It has been recognized that the topology of molecular networks provides information about the certainty and nature of individual interactions. Thus, network…”
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The sbv IMPROVER Systems Toxicology computational challenge: Identification of human and species-independent blood response markers as predictors of smoking exposure and cessation status
Published in Computational toxicology (01-02-2018)“…•Crowdsourcing enables independent and unbiased evaluations of computational methods.•Markers predictive of smoking status were identified in blood gene…”
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Extensive mass spectrometry-based analysis of the fission yeast proteome: the Schizosaccharomyces pombe PeptideAtlas
Published in Molecular & cellular proteomics (01-06-2013)“…We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe,…”
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Subsequence-based feature map for protein function classification
Published in Computational biology and chemistry (01-04-2008)“…Automated classification of proteins is indispensable for further in vivo investigation of excessive number of unknown sequences generated by large scale…”
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Gene regulatory network inference from gene expression dataset using autoencoder
Published in 2018 26th Signal Processing and Communications Applications Conference (SIU) (01-05-2018)“…Genes, specific stretches of DNA sequences, encode for gene products to perform a number of biological functions required for life. Gene expression is the…”
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Conference Proceeding -
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Gene selection and classification of pancreatic microarray datasets
Published in 2017 25th Signal Processing and Communications Applications Conference (SIU) (01-05-2017)“…Microarray data is measured with numerous features, selection of the most important genes from such data sets is an essential step towards maximizing…”
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Conference Proceeding -
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Prediction of return in online shopping
Published in 2015 23nd Signal Processing and Communications Applications Conference (SIU) (01-05-2015)“…Mail order business gains popularity day by day. One major problem for the retailers is the high return rates. The incurred cost of returns forces companies to…”
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Conference Proceeding -
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Subsequence profile map for protein fold recognition
Published in 2016 24th Signal Processing and Communication Application Conference (SIU) (01-05-2016)“…Information belonging to 3D structures of the proteins, which are the most fundamental macromolecules of life, plays a key role in bioinformatics studies…”
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Conference Proceeding -
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Glasses detection in face images using histogram of Oriented Gradients
Published in 2014 22nd Signal Processing and Communications Applications Conference (SIU) (01-04-2014)“…Glasses detection is one of attractive tasks in image processing since it increases the performance of face recognition systems. In this study, we aimed to…”
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Conference Proceeding -
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A Novel Model-based Method for Feature Extraction from Protein Sequences for Classification
Published in 2006 IEEE 14th Signal Processing and Communications Applications (2006)“…Representation of amino-acid sequences constitutes the key point in classification of proteins into functional or structural classes. The representation should…”
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Conference Proceeding -
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Large-scale De Novo Prediction of Physical Protein-Protein Association
Published in Molecular & cellular proteomics (01-11-2011)“…Information about the physical association of proteins is extensively used for studying cellular processes and disease mechanisms. However, complete…”
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Journal Article -
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Species translatable blood gene signature as a marker of exposure to smoking: Computational approaches of the top ranked teams in the sbv IMPROVER Systems Toxicology Challenge
Published in Computational toxicology (01-02-2018)“…•Common blood mRNAs predict current exposure to cigarette smoke in mouse and human.•Organism specific signature is more accurate for prediction of current…”
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Extensive Mass Spectrometry-based Analysis of the Fission Yeast Proteome
Published in Molecular & cellular proteomics (01-06-2013)“…We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe,…”
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Journal Article -
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Subsequence Feature Maps for Protein Function Annotation
Published 01-01-2008“…With the advances in sequencing technologies, the number of protein sequences with unknown function increases rapidly. Hence, computational methods for…”
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Dissertation