Search Results - "Sarabia , F"
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Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups
Published in Hepatology (Baltimore, Md.) (01-01-2017)“…Despite being the most common liver cancer in children, hepatoblastoma (HB) is a rare neoplasm. Consequently, few pretreatment tumors have been molecularly…”
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USP6 activation in nodular fasciitis by promoter-swapping gene fusions
Published in Modern pathology (01-11-2017)“…Nodular fasciitis is a self-limited myofibroblastic lesion that can be misdiagnosed as a sarcoma as a result of its rapid growth, cellularity, and sometimes…”
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A 40-month multicentre, randomised placebo-controlled study to assess the efficacy and carry-over effect of repeated intra-articular injections of hyaluronic acid in knee osteoarthritis: the AMELIA project
Published in Annals of the rheumatic diseases (01-11-2011)“…AMELIA (OsteoArthritis Modifying Effects of Long-term Intra-articular Adant) was designed to compare against placebo the efficacy and safety of repeated…”
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MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma
Published in Scientific reports (03-02-2021)“…Hepatoblastoma (HB) is the most common pediatric liver malignancy. High-risk patients have poor survival, and current chemotherapies are associated with…”
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Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation
Published in Pediatric blood & cancer (01-07-2019)“…Background Pediatric hepatocellular carcinoma (HCC) is a rare liver tumor in children with a poor prognosis. Comprehensive molecular profiling to understand…”
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Emerging pollutants in the Esmeraldas watershed in Ecuador: discharge and attenuation of emerging organic pollutants along the San Pedro-Guayllabamba-Esmeraldas rivers
Published in Environmental science--processes & impacts (01-01-2015)“…Water quality characteristics and emerging organic pollutants were sampled along the San Pedro-Guayllabamba-Esmeraldas River and its main water pollution…”
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Integrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma
Published in Pediatric blood & cancer (01-01-2021)“…Background Pediatric papillary thyroid carcinoma (PTC) is clinically and biologically distinct from adult PTC. We sequenced a cohort of clinically annotated…”
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A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma
Published in Scientific reports (19-12-2017)“…Currently, preclinical testing of therapies for hepatoblastoma (HB) is limited to subcutaneous and intrasplenic xenograft models that do not recapitulate the…”
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Author Correction: MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma
Published in Scientific reports (01-10-2021)Get full text
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Mucoepidermoid Carcinoma in Children: A Single Institutional Experience
Published in Pediatric blood & cancer (01-01-2016)“…Purpose and objective To determine the clinicopathologic and molecular features and outcome of children with mucoepidermoid carcinoma (MEC). Methods A…”
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Navigating relapsed hepatoblastoma: Predictive factors and surgical treatment strategy
Published in Cancer medicine (Malden, MA) (01-12-2023)“…Objective Hepatoblastoma (HB) is the most common primary hepatic malignancy in childhood. Relapse occurs in more than 50% of high‐risk patients with a high…”
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Synthesis of tetrazole fused azepanes and quantum chemical topology study on the mechanism of the intramolecular cycloaddition reaction
Published in RSC advances (2017)“…The synthesis of novel tetrazolo azepanes from azido nitriles by 1,3 intramolecular dipolar cycloaddition starting from monosaccharide derivatives is…”
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Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis
Published in The pharmacogenomics journal (01-04-2016)“…Genetic biomarkers could be useful for orienting treatment of patients with rheumatoid arthritis (RA), but none has been convincingly validated yet. Putative…”
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Synthesis of epothilones A and B in solid and solution phase
Published in Nature (London) (15-05-1997)“…Epothilones A and B, two compounds that have been recently isolated from myxobacterium Sorangium cellulosum strain 90, have generated intense interest among…”
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Aminooxy analog of histamine is an efficient inhibitor of mammalian L-histidine decarboxylase: combined in silico and experimental evidence
Published in Amino acids (01-03-2014)“…Histamine plays highlighted roles in the development of many common, emergent and rare diseases. In mammals, histamine is formed by decarboxylation of…”
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Dose escalation of the anti-TNF-α agents in patients with rheumatoid arthritis. A systematic review
Published in Rheumatology (Oxford, England) (01-03-2007)“…Objective. To estimate the proportion of rheumatoid arthritis (RA) patients on anti-tumour necrosis factor (anti-TNF) who require dose escalation. Methods…”
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Adalimumab for treating rheumatoid arthritis
Published in Cochrane database of systematic reviews (20-07-2005)“…Adalimumab is a fully human anti-TNFalpha monoclonal antibody. Published studies indicate that its use in patients with RA can be effective and safe. The aim…”
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Total Syntheses of Epothilones A and B via a Macrolactonization-Based Strategy
Published in Journal of the American Chemical Society (27-08-1997)“…The total syntheses of epothilones A (1) and B (2) and several analogues thereof are described. The reported strategy relies on a macrolactonization approach…”
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Cost-Utility of Rheumatoid Arthritis Monotherapy with Tocilizumab in Spain
Published in Value in health (01-11-2013)Get full text
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