Search Results - "Sara Ferrando-Martinez"
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CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection
Published in Blood (02-06-2011)“…The immunomodulatory receptor CD300a is expressed on human B cells. Naive B cells express very low levels of this receptor, whereas memory B cells and…”
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Editorial: The Interplay Between Immune Activation and Cardiovascular Disease During Infection, Autoimmunity and Aging: The Role of T Cells
Published in Frontiers in immunology (24-06-2021)Get full text
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Role of Defective Thymic Function in Onset of Ganciclovir-Resistant Cytomegalovirus after Cord Blood Transplantation
Published in Clinical and Vaccine Immunology (01-12-2012)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Functional Exhaustion of HBV-Specific CD8 T Cells Impedes PD-L1 Blockade Efficacy in Chronic HBV Infection
Published in Frontiers in immunology (13-09-2021)“…BackgroundA functional cure for chronic HBV could be achieved by boosting HBV-specific immunity. In vitro studies show that immunotherapy could be an effective…”
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Long-term immunovirogical effect and tolerability of a maraviroc-containing regimen in routine clinical practice
Published in Current HIV research (01-09-2010)“…to analyze the long-term immunovirological effect and tolerability of a maraviroc-containing antiretroviral therapy in viraemic and pretreated HIV-infected…”
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HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue
Published in Cell reports (Cambridge) (19-12-2017)“…Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8+ T cells play a critical role in control of HIV, but their…”
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Circulating metabolomic profile can predict dyslipidemia in HIV patients undergoing antiretroviral therapy
Published in Atherosclerosis (01-06-2018)“…Dyslipidemia in HIV-infected patients is unique and pathophysiologically associated with host factors, HIV itself and the use of antiretroviral therapy (ART)…”
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Long-Term Suppressive Combined Antiretroviral Treatment Does Not Normalize the Serum Level of Soluble CD14
Published in The Journal of infectious diseases (15-04-2013)“…Levels of soluble CD14 (sCD14) were longitudinally measured in 85 human immunodeficiency virus (HIV)—infected subjects during long-term receipt of suppressive…”
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Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells
Published in PloS one (01-07-2016)“…Little is known about the expression of inhibitory molecules cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed-death-1 (PD-1) on Mycobacterium…”
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rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors
Published in Journal for immunotherapy of cancer (12-03-2024)“…BackgroundRecombinant human interleukin (rhIL)-7-hyFc (efineptakin alfa; NT-I7) is a potent T-cell amplifier, with two IL-7 molecules fused to IgD/IgG4…”
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rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors
Published in Journal for immunotherapy of cancer (23-07-2024)“…BackgroundChimeric antigen receptor T-cell (CAR-T) therapy has achieved remarkable remission in patients with B-cell malignancies. However, its efficacy in…”
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Immune Correlates of Natural HIV Elite Control and Simultaneous HCV Clearance-Supercontrollers
Published in Frontiers in immunology (10-12-2018)“…HIV-elite controllers are a minority group of HIV-infected patients with the ability to maintain undetectable HIV viremia for long time periods without…”
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Reduced sTWEAK and increased sCD163 levels in HIV-infected patients: modulation by antiretroviral treatment, HIV replication and HCV co-infection
Published in PloS one (04-03-2014)“…Patients infected with the human immunodeficiency virus (HIV) have an increased risk of cardiovascular disease due to increased inflammation and persistent…”
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Low Thymic Output, Peripheral Homeostasis Deregulation, and Hastened Regulatory T Cells Differentiation in Children with 22q11.2 Deletion Syndrome
Published in The Journal of pediatrics (01-04-2014)“…Objective To perform an extensive analysis of the immune status of asymptomatic children with the 22q11.2 deletion syndrome, with special emphasis on the…”
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816 NT-I7 and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that favors anti-tumor efficacy in combination with checkpoint inhibitors
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundNT-I7 (efineptakin alfa; rhIL-7-hyFc) is a potent T-cell amplifier, with two IL-7 molecules fused to IgD/IgG4 elements. NT-I7 promotes extensive…”
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The Role of Interleukin-7 in the Formation of Tertiary Lymphoid Structures and Their Prognostic Value in Gastrointestinal Cancers
Published in Journal of Immunotherapy and Precision Oncology (01-11-2022)“…Immunotherapies for the treatment of solid tumors continue to develop in preclinical and clinical research settings. Unfortunately, for many patients the tumor…”
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HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection
Published in JHEP reports (01-09-2019)“…Current therapies for chronic hepatitis B virus (HBV) infection control viral replication but do not eliminate the risk of progression to hepatocellular…”
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652 NT-I7 (efineptakin alfa), a long-acting IL-7, in combination with pembrolizumab improves T cell fitness in heavily pretreated subjects with gastrointestinal tumors
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundCancer patients include various populations with underlying immune dysfunction, like transplant patients or subjects with chronic infections, and…”
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Differential Gag-Specific Polyfunctional T Cell Maturation Patterns in HIV-1 Elite Controllers
Published in Journal of Virology (01-04-2012)“…A small fraction of HIV-infected individuals (<1%), referred to as elite controllers (EC), are able to maintain undetectable viral loads indefinitely without…”
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Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression
Published in PloS one (01-12-2015)“…The role of PD-1 expression on CD4 T cells during HIV infection is not well understood. Here, we describe the differential expression of PD-1 in CD127high CD4…”
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