Search Results - "Sara Aiman"

Multi-epitope chimeric vaccine design against emerging Monkeypox virus via reverse vaccinology techniques- a bioinformatics and immunoinformatics approach by Aiman, Sara, Alhamhoom, Yahya, Ali, Fawad, Rahman, Noor, Rastrelli, Luca, Khan, Asifullah, Farooq, Qurat ul Ain, Ahmed, Abbas, Khan, Asif, Li, Chunhua

“…The emerging monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes infections in humans similar to smallpox. Since May 2022, cases of monkeypox (MPX)…”
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Core-genome-mediated promising alternative drug and multi-epitope vaccine targets prioritization against infectious Clostridium difficile by Aiman, Sara, Farooq, Qurrat Ul Ain, Han, Zhongjie, Aslam, Muneeba, Zhang, Jilong, Khan, Asifullah, Ahmad, Abbas, Li, Chunhua, Ali, Yasir

“…Prevention of Clostridium difficile infection is challenging worldwide owing to its high morbidity and mortality rates. C. difficile is currently being…”
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Vaccinomics-aided next-generation novel multi-epitope-based vaccine engineering against multidrug resistant Shigella Sonnei: Immunoinformatics and chemoinformatics approaches by Aiman, Sara, Ahmad, Abbas, Khan, Asifullah, Ali, Yasir, Malik, Abdul, Alkholief, Musaed, Akhtar, Suhail, Khan, Raham Sher, Li, Chunhua, Jalil, Fazal

“…Shigella sonnei is a gram-negative bacterium and is the primary cause of shigellosis in advanced countries. An exceptional rise in the prevalence of the…”
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Vaccinomics-based next-generation multi-epitope chimeric vaccine models prediction against Leishmania tropica - a hierarchical subtractive proteomics and immunoinformatics approach by Aiman, Sara, Ahmad, Abbas, Khan, Azmat Ali, Alanazi, Amer M., Samad, Abdus, Ali, Syed Luqman, Li, Chunhua, Ren, Zhiguang, Khan, Asifullah, Khattak, Saadullah

“…Leishmania tropica is a vector-borne parasitic protozoa that is the leading cause of leishmaniasis throughout the global tropics and subtropics. L. tropica is…”
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A systems biology-driven approach to construct a comprehensive protein interaction network of influenza A virus with its host by Farooq, Qurat Ul Ain, Shaukat, Zeeshan, Aiman, Sara, Zhou, Tong, Li, Chunhua

“…Influenza A virus (IAV) infection is a serious public health problem not only in South East Asia but also in European and African countries. Scientists are…”
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Core genome mediated potential vaccine targets prioritization against Clostridium difficile via reverse vaccinology - an immuno-informatics approach by Sara Aiman, Fawad Ali, Asad Zia, Muneeba Aslam, Zhongjie Han, Qurat ul Ain Farooq, Sulaiman Shams, Asifullah Khan, Chunhua Li

“…The emergence of multi-drug resistance in clostridium difficile is an urgent bio-threat associated with high morbidity and mortality. The availability of core…”
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Annotation of Potential Vaccine Targets and Designing of mRNA-Based Multi-Epitope Vaccine against Lumpy Skin Disease Virus via Reverse Vaccinology and Agent-Based Modeling by Kakakhel, Sehrish, Ahmad, Abbas, Mahdi, Wael A, Alshehri, Sultan, Aiman, Sara, Begum, Sara, Shams, Sulaiman, Kamal, Mehnaz, Imran, Mohd, Shakeel, Faiyaz, Khan, Asifullah

“…Lumpy skin disease is a fatal emerging disease of cattle, which has started to gain extensive attention due to its rapid incursions across the globe. The…”
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Molecular Mimicry Analyses Unveiled the Human Herpes Simplex and Poxvirus Epitopes as Possible Candidates to Incite Autoimmunity by Begum, Sara, Aiman, Sara, Ahmad, Shujaat, Samad, Abdus, Almehmadi, Mazen, Allahyani, Mamdouh, Aljuaid, Abdulelah, Afridi, Sahib Gul, Khan, Asifullah

“…Clinical epidemiological studies have reported that viral infections cause autoimmune pathology in humans. Host-pathogen protein sequences and structure-based…”
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Comparative Proteomics and Genome-Wide Druggability Analyses Prioritized Promising Therapeutic Targets against Drug-Resistant Leishmania tropica by Aiman, Sara, Alzahrani, A Khuzaim, Ali, Fawad, Abida, Imran, Mohd, Kamal, Mehnaz, Usman, Muhammad, Thabet, Hamdy Khamees, Li, Chunhua, Khan, Asifullah

“…is a tropical parasite causing cutaneous leishmaniasis (CL) in humans. Leishmaniasis is a serious public health threat, affecting an estimated 350 million…”
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Immunoinformatics-based multi-epitope vaccine design for the re-emerging monkeypox virus by Farzan, Mahour, Farzan, Mahan, Mirzaei, Yousef, Aiman, Sara, Azadegan-Dehkordi, Fatemeh, Bagheri, Nader

“…On May 7, 2022, WHO reported a new monkeypox case. By May 2023 over 80,000 cases had been reported worldwide outside previously endemic nations. (This…”
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Immunoinformatic-guided novel mRNA vaccine designing to elicit immunogenic responses against the endemic Monkeypox virus by Aiman, Sara, Ali, Yasir, Malik, Abdul, Alkholief, Musaed, Ahmad, Abbas, Akhtar, Suhail, Ali, Sajid, Khan, Asifullah, Li, Chunhua, Shams, Sulaiman

“…Monkeypox virus (MPXV) is an orthopoxvirus, causing zoonotic infections in humans with smallpox-like symptoms. The WHO reported MPXV cases in May 2022 and the…”
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Immunoinformatics-based potential multi-peptide vaccine designing against Jamestown Canyon Virus (JCV) capable of eliciting cellular and humoral immune responses by Shahab, Muhammad, Aiman, Sara, Alshammari, Abdulrahman, Alasmari, Abdullah F., Alharbi, Metab, Khan, Abbas, Wei, Dong-Qing, Zheng, Guojun

“…Jamestown Canyon virus (JCV) is a deadly viral infection transmitted by various mosquito species. This mosquito-borne virus belongs to Bunyaviridae family,…”
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A comprehensive protein interaction map and druggability investigation prioritized dengue virus NS1 protein as promising therapeutic candidate by Farooq, Qurrat Ul Ain, Aiman, Sara, Ali, Yasir, Shaukat, Zeeshan, Ali, Yasir, Khan, Asifullah, Samad, Abdus, Wadood, Abdul, Li, Chunhua

“…Dengue Virus (DENV) is a serious threat to human life worldwide and is one of the most dangerous vector-borne diseases, causing thousands of deaths annually…”
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Inferring Virus-Host relationship between HPV and its host Homo sapiens using protein interaction network by Farooq, Qurat ul Ain, Shaukat, Zeeshan, Zhou, Tong, Aiman, Sara, Gong, Weikang, Li, Chunhua

“…Human papilloma virus (HPV) is a serious threat to human life globally with over 100 genotypes including cancer causing high risk HPVs. Study on protein…”
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Protein-protein interactions: Methods, databases, and applications in virus-host study by Farooq, Qurat Ul Ain, Shaukat, Zeeshan, Aiman, Sara, Li, Chun-Hua

“…Almost all the cellular processes in a living system are controlled by proteins: They regulate gene expression, catalyze chemical reactions, transport small…”
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The in silico identification of small molecules for protein-protein interaction inhibition in AKAP-Lbc–RhoA signaling complex by Khan, Asifullah, Munir, Mehwish, Aiman, Sara, Wadood, Abdul, Khan, Arif-ullah

“…[Display omitted] •The A-Kinase Anchoring Protein, i.e. AKAP-Lbc is involved in cardiac repolarization by mediating Rho GTPases activation.•The oncogenic…”
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Vaccinomics-aided next-generation novel multi-epitope-based vaccine engineering against multidrug resistant Shigella Sonnei: Immunoinformatics and chemoinformatics approaches by Sara Aiman, Abbas Ahmad, Asifullah Khan, Yasir Ali, Abdul Malik, Musaed Alkholief, Suhail Akhtar, Raham Sher Khan, Chunhua Li, Fazal Jalil

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The In Silico Characterization of a Salicylic Acid Analogue Coding Gene Clusters in Selected Pseudomonas fluorescens Strains by Shehroz, Muhammad, Aslam, Muneeba, Ali Khan, Munazza, Aiman, Sara, Gul Afridi, Sahib, Khan, Asifullah

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