Search Results - "Sara, Susan J"
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Orienting and Reorienting: The Locus Coeruleus Mediates Cognition through Arousal
Published in Neuron (Cambridge, Mass.) (04-10-2012)“…Mood, motivation, attention, and arousal are behavioral states having a profound impact on cognition. Behavioral states are mediated though the peripheral…”
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The locus coeruleus and noradrenergic modulation of cognition
Published in Nature reviews. Neuroscience (01-03-2009)“…Key Points The noradrenergic nucleus locus coeruleus (LC) is a tiny cluster of cells located bilaterally in the pons just under the fourth ventricle. Despite…”
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Sleep to Remember
Published in The Journal of neuroscience (18-01-2017)“…Scientific investigation into the possible role of sleep in memory consolidation began with the early studies of Jenkins and Dallenbach (1924). Despite nearly…”
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Noradrenergic Neurons of the Locus Coeruleus Are Phase Locked to Cortical Up-Down States during Sleep
Published in Cerebral cortex (New York, N.Y. 1991) (01-02-2012)“…Nonrapid eye movement (NREM) sleep is characterized by periodic changes in cortical excitability that are reflected in the electroencephalography (EEG) as…”
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Ripple-Triggered Stimulation of the Locus Coeruleus during Post-Learning Sleep Disrupts Ripple/Spindle Coupling and Impairs Memory Consolidation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-05-2016)“…Experience-induced replay of neuronal ensembles occurs during hippocampal high-frequency oscillations, or ripples. Post-learning increase in ripple rate is…”
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Activation of prefrontal cortex and striatal regions in rats after shifting between rules in a T-maze
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-07-2023)“…Prefrontal cortical and striatal areas have been identified by inactivation or lesion studies to be required for behavioral flexibility, including selecting…”
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Network reset: a simplified overarching theory of locus coeruleus noradrenaline function
Published in Trends in neurosciences (Regular ed.) (01-11-2005)“…Unraveling the functional role of neuromodulatory systems has been a major challenge for cognitive neuroscience, giving rise to theories ranging from a simple…”
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The influence of learning on sleep slow oscillations and associated spindles and ripples in humans and rats
Published in The European journal of neuroscience (01-03-2009)“…The mechanisms underlying off‐line consolidation of memory during sleep are elusive. Learning of hippocampus‐dependent tasks increases neocortical slow…”
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Hippocampal sharp wave/ripples during sleep for consolidation of associative memory
Published in PloS one (20-08-2009)“…The beneficial effect of sleep on memory has been well-established by extensive research on humans, but the neurophysiological mechanisms remain a matter of…”
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Reactivation, retrieval, replay and reconsolidation in and out of sleep: connecting the dots
Published in Frontiers in behavioral neuroscience (13-12-2010)“…The neurobiology of memory has taken on a new look over the past decade. Re-discovery of cue-dependent amnesia, wide availability of functional imaging tools…”
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Elevated Sleep Spindle Density after Learning or after Retrieval in Rats
Published in The Journal of neuroscience (13-12-2006)“…Non-rapid eye movement sleep has been strongly implicated in consolidation of both declarative and procedural memory in humans. Elevated sleep-spindle density…”
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Learning-Dependent, Transient Increase of Activity in Noradrenergic Neurons of Locus Coeruleus during Slow Wave Sleep in the Rat: Brain Stem–Cortex Interplay for Memory Consolidation?
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2008)“…Memory consolidation during sleep is regaining attention due to a wave of recent reports of memory improvements after sleep or deficits after sleep…”
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Sustained increase in hippocampal sharp-wave ripple activity during slow-wave sleep after learning
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-04-2008)“…High-frequency oscillations, known as sharp-wave/ripple (SPW-R) complexes occurring in hippocampus during slow-wave sleep (SWS), have been proposed to promote…”
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Hippocampal Sharp Wave-Ripples Linked to Slow Oscillations in Rat Slow-Wave Sleep
Published in Journal of neurophysiology (01-07-2006)“…1 Department of Neuroendocrinology, University of Lübeck, Lübeck, Germany; 2 Neuromodulation, Neuroplasticity and Cognition, Centre National de la Recherche…”
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Locus coeruleus noradrenergic neurons phase-lock to prefrontal and hippocampal infra-slow rhythms that synchronize to behavioral events
Published in Frontiers in cellular neuroscience (21-03-2023)“…The locus coeruleus (LC) is the primary source of noradrenergic projections to the forebrain, and, in prefrontal cortex, is implicated in decision-making and…”
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Reward expectation, orientation of attention and locus coeruleus-medial frontal cortex interplay during learning
Published in The European journal of neuroscience (01-08-2004)“…Regulation of attention and promotion of behavioural flexibility are functions attributed to both the noradrenergic nucleus locus coeruleus (LC) and the…”
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Locus Coeruleus in time with the making of memories
Published in Current opinion in neurobiology (01-12-2015)“…Highlights • Locus Coeruleus noradrenergic system modulates all aspects of memory processing. • LC most heavily innervates mPFC. • LC reorients attention. • LC…”
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Locus coeruleus: a new look at the blue spot
Published in Nature reviews. Neuroscience (01-11-2020)“…The locus coeruleus (LC), or ‘blue spot’, is a small nucleus located deep in the brainstem that provides the far-reaching noradrenergic neurotransmitter system…”
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Mapping of olfactory memory circuits: region-specific c-fos activation after odor-reward associative learning or after its retrieval
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-05-2002)“…Although there is growing knowledge about intracellular mechanisms underlying neuronal plasticity and memory consolidation and reconsolidation after retrieval,…”
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Noradrenergic Action in Prefrontal Cortex in the Late Stage of Memory Consolidation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-07-2004)“…These experiments investigated the role of the noradrenergic system in the late stage of memory consolidation and in particular its action at beta receptors in…”
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