Search Results - "Sara, P."

Radical‐Promoted C−C Bond Cleavage: A Deconstructive Approach for Selective Functionalization by Morcillo, Sara P.

“…Just as “Deconstructivism” appeared as a novel movement in architecture in the 1980s, deconstructive approaches have recently emerged as excellent strategies…”
Get full text

Hydroxylamine Derivatives as Nitrogen‐Radical Precursors in Visible‐Light Photochemistry by Davies, Jacob, Morcillo, Sara P., Douglas, James J., Leonori, Daniele

“…In recent years, hydroxylamines derivatives have been exploited as nitrogen‐radical precursors in visible‐light photochemistry. Their ability to serve as…”
Get full text

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells by Kurt, Ibrahim C., Zhou, Ronghao, Iyer, Sowmya, Garcia, Sara P., Miller, Bret R., Langner, Lukas M., Grünewald, Julian, Joung, J. Keith

“…CRISPR-guided DNA cytosine and adenine base editors are widely used for many applications 1 – 4 but primarily create DNA base transitions (that is,…”
Get full text

Photoinduced Remote Functionalisations by Iminyl Radical Promoted C−C and C−H Bond Cleavage Cascades by Dauncey, Elizabeth M., Morcillo, Sara P., Douglas, James J., Sheikh, Nadeem S., Leonori, Daniele

“…A photoinduced cascade strategy leading to a variety of differentially functionalised nitriles and ketones has been developed. These reactions rely on the…”
Get full text

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors by Grünewald, Julian, Zhou, Ronghao, Garcia, Sara P., Iyer, Sowmya, Lareau, Caleb A., Aryee, Martin J., Joung, J. Keith

“…CRISPR–Cas base-editor technology enables targeted nucleotide alterations, and is being increasingly used for research and potential therapeutic applications 1…”
Get full text

Evolution-guided engineering of small-molecule biosensors by Snoek, Tim, Chaberski, Evan K, Ambri, Francesca, Kol, Stefan, Bjørn, Sara P, Pang, Bo, Barajas, Jesus F, Welner, Ditte H, Jensen, Michael K, Keasling, Jay D

“…Allosteric transcription factors (aTFs) have proven widely applicable for biotechnology and synthetic biology as ligand-specific biosensors enabling real-time…”
Get full text

Assessment of computational methods for the analysis of single-cell ATAC-seq data by Chen, Huidong, Lareau, Caleb, Andreani, Tommaso, Vinyard, Michael E, Garcia, Sara P, Clement, Kendell, Andrade-Navarro, Miguel A, Buenrostro, Jason D, Pinello, Luca

“…Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of…”
Get full text

Qualitative Study of Barriers to Concussive Symptom Reporting in High School Athletics by Chrisman, Sara P., M.D., M.P.H, Quitiquit, Celeste, M.D, Rivara, Frederick P., MD., M.P.H

“…Abstract Purpose To identify barriers to concussive symptom reporting in high school athletics. Methods We conducted a qualitative focus group study with…”
Get full text

Sex and Gender Differences in Bacterial Infections by Dias, Sara P, Brouwer, Matthijs C, van de Beek, Diederik

“…There is a growing awareness of the importance of sex and gender in medicine and research. Women typically have stronger immune responses to self and foreign…”
Get full text

Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals by Morcillo, Sara P., Dauncey, Elizabeth M., Kim, Ji Hye, Douglas, James J., Sheikh, Nadeem S., Leonori, Daniele

“…The selective functionalization of C(sp3)−H bonds at distal positions to functional groups is a challenging task in synthetic chemistry. Reported here is a…”
Get full text

Advancing Equity in Faculty Hiring with Diversity Statements by Bombaci, Sara P, Pejchar, Liba

“…Abstract Hiring diverse candidates and creating an inclusive and equitable climate has emerged as a top priority for the scientific community. Diversity…”
Get full text

Extraction and purification of high‐value metabolites from microalgae: essential lipids, astaxanthin and phycobiliproteins by Cuellar‐Bermudez, Sara P., Aguilar‐Hernandez, Iris, Cardenas‐Chavez, Diana L., Ornelas‐Soto, Nancy, Romero‐Ogawa, Miguel A., Parra‐Saldivar, Roberto

“…Summary The marked trend and consumers growing interest in natural and healthy products have forced researches and industry to develop novel products with…”
Get full text

CRISPR DNA base editors with reduced RNA off-target and self-editing activities by Grünewald, Julian, Zhou, Ronghao, Iyer, Sowmya, Lareau, Caleb A., Garcia, Sara P., Aryee, Martin J., Joung, J. Keith

“…Cytosine or adenine base editors (CBEs or ABEs) can introduce specific DNA C-to-T or A-to-G alterations 1 – 4 . However, we recently demonstrated that they can…”
Get full text

High levels of AAV vector integration into CRISPR-induced DNA breaks by Hanlon, Killian S., Kleinstiver, Benjamin P., Garcia, Sara P., Zaborowski, Mikołaj P., Volak, Adrienn, Spirig, Stefan E., Muller, Alissa, Sousa, Alexander A., Tsai, Shengdar Q., Bengtsson, Niclas E., Lööv, Camilla, Ingelsson, Martin, Chamberlain, Jeffrey S., Corey, David P., Aryee, Martin J., Joung, J. Keith, Breakefield, Xandra O., Maguire, Casey A., György, Bence

“…Adeno-associated virus (AAV) vectors have shown promising results in preclinical models, but the genomic consequences of transduction with AAV vectors encoding…”
Get full text

ASO Author Reflections: Achieving Equity in Thyroid Cancer Treatment—More Work Ahead by Ginzberg, Sara P., Wachtel, Heather

Get full text

Octagon‐Embedded Carbohelicene as a Chiral Motif for Circularly Polarized Luminescence Emission of Saddle‐Helix Nanographenes by Medel, Miguel A., Tapia, Rubén, Blanco, Victor, Miguel, Delia, Morcillo, Sara P., Campaña, Araceli G.

“…We report a new family of hexa‐peri‐hexabenzocoronene (HBC)‐based helical nanographenes incorporating π‐extended carbo[5]helicenes bearing an octagonal…”
Get full text

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis by Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E.

“…Enhancers, critical determinants of cellular identity, are commonly recognized by correlative chromatin marks and gain-of-function potential, although only…”
Get full text

A New Game Plan for Concussion Education by Kroshus, Emily, Chrisman, Sara P. D.

“…Despite state laws requiring concussion education for youth sport stakeholders and a proliferation of educational programs, there has been little demonstrated…”
Get full text

A Definitive Answer to the Effect of Screen Time on Concussion Recovery by Chrisman, Sara P D

Get more information

Photosynthetic bioenergy utilizing CO2: an approach on flue gases utilization for third generation biofuels by Cuellar-Bermudez, Sara P., Garcia-Perez, Jonathan S., Rittmann, Bruce E., Parra-Saldivar, Roberto

“…One of the most important industrial activities related to the greenhouse gases emissions is the cement manufacturing process, which produces large amounts of…”
Get full text