Search Results - "Saqallah, Fadi G"

Unlocking the Conformational Changes of P2Y12: Exploring an Acridinone Compound’s Effect on Receptor Activity and Conformation by Al-Najjar, Belal O., Saqallah, Fadi G.

“…The P2Y12 receptor is an important member of the purinergic receptor family, known for its critical role in platelet activation and thrombosis. In our…”
Get full text

Pulmonary Delivery of Anticancer Drugs via Lipid-Based Nanocarriers for the Treatment of Lung Cancer: An Update by Abdulbaqi, Ibrahim M, Assi, Reem Abou, Yaghmur, Anan, Darwis, Yusrida, Mohtar, Noratiqah, Parumasivam, Thaigarajan, Saqallah, Fadi G, Wahab, Habibah A

“…Lung cancer (LC) is the leading cause of cancer-related deaths, responsible for approximately 18.4% of all cancer mortalities in both sexes combined. The use…”
Get full text

Heterocyclic Substitutions Greatly Improve Affinity and Stability of Folic Acid towards FRα. an In Silico Insight by Al-Thiabat, Mohammad G, Saqallah, Fadi G, Gazzali, Amirah Mohd, Mohtar, Noratiqah, Yap, Beow Keat, Choong, Yee Siew, Wahab, Habibah A

“…Folate receptor alpha (FRα) is known as a biological marker for many cancers due to its overexpression in cancerous epithelial tissue. The folic acid (FA)…”
Get full text

Antimicrobial activity and molecular docking screening of bioactive components of Antirrhinum majus (snapdragon) aerial parts by Saqallah, Fadi G., Hamed, Wafaa M., Talib, Wamidh H., Dianita, Roza, Wahab, Habibah A.

“…Antirrhinum majus (Snapdragon) is a perennial Mediterranean-native plant that is commonly used for mass display. Few reports acknowledged the traditional use…”
Get full text

QSAR, structure-based pharmacophore modelling and biological evaluation of novel platelet ADP receptor (P2Y) antagonist by Al-Najjar, Belal O, Abbas, Manal A, Sibai, Obada A, Saqallah, Fadi G, Al-Kabariti, Aya Y

“…P2Y 12 has a key role in platelet aggregation and thrombus formation via an ADP-induced platelet activation mechanism. Recently, P2Y 12 antagonists have become…”
Get full text

Computational study of nitro-benzylidene phenazine as dengue virus-2 NS2B-NS3 protease inhibitor by Salin, Nurul Hanim, Hariono, Maywan, Khalili, Nur Sarah Dyana, Zakaria, Iffah Izzati, Saqallah, Fadi G., Mohamad Taib, Mohamad Nurul Azmi, Kamarulzaman, Ezatul Ezleen, Wahab, Habibah A., Khawory, Muhammad Hidhir

“…According to the World Health Organisation (WHO), as of week 23 of 2022, there were more than 1,311 cases of dengue in Malaysia, with 13 deaths reported…”
Get full text

Medicinal plants’ proposed nanocomposites for the management of endocrine disorders by Al Zarzour, Raghdaa Hamdan, Kamarulzaman, Ezatul Ezleen, Saqallah, Fadi G., Zakaria, Fauziahanim, Asif, Muhammad, Abdul Razak, Khairul Niza

“…Extensive attention has been focused on herbal medicine for the treatment of different endocrine disorders. In fact, compelling scientific evidence indicates…”
Get full text

In Vivo Evaluation of Antirrhinum majus ' Wound-Healing Activity by Saqallah, Fadi G, Hamed, Wafaa M, Talib, Wamidh H

“…Mediterranean-native perennial plant was scrutinized in this study for its antioxidant activity and its total phenolic content in order to test for the plant's…”
Get full text

Regulation of adipogenesis by exosomal milk miRNA by Abbas, Manal A., Al-Saigh, Noor Nadhim, Saqallah, Fadi G.

“…Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and tissue distribution of milk exosomes was reported in newborn and…”
Get full text

Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease by Saqallah, Fadi G., Abbas, Manal A., Wahab, Habibah A.

“…Dengue virus (DENV) is an arbovirus widespread through tropical and subtropical areas. It is transmitted to humans through Aedes mosquitoes. Infections with…”
Get full text

Unlocking the Conformational Changes of P2Y[sub.12]: Exploring an Acridinone Compound’s Effect on Receptor Activity and Conformation by Al-Najjar, Belal O, Saqallah, Fadi G

“…The P2Y[sub.12] receptor is an important member of the purinergic receptor family, known for its critical role in platelet activation and thrombosis. In our…”
Get full text

P2Y12 antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies by Al-Najjar, Belal O., Saqallah, Fadi G., Abbas, Manal A., Al-Hijazeen, Serena Z., Sibai, Obada A.

“…P2Y12 is a platelet surface protein which is responsible for the amplification of P2Y1 response. It plays a crucial role in platelet aggregation and thrombus…”
Get full text

Substituted furan-carboxamide and Schiff base derivatives as potential hypolipidemic compounds: evaluation in Triton WR-1339 hyperlipidemic rat model by Hussein, Buthaina, Alwahsh, Mohammad, Al-Hiari, Yusuf, Bourghli, Laurance, Al-Jammal, Basmah, Al-Qirim, Tareq, AlBujuq, Nader R., Abu-zaid, Rania, Saqallah, Fadi G., Hamadneh, Lama

“…Substituted furan carboxamide and Schiff base derivatives were evaluated for their hypolipidemic activity. Fourteen derivatives were synthesised:…”
Get full text

Correction: Substituted furan-carboxamide and Schiff base derivatives as potential hypolipidemic compounds: evaluation in Triton WR-1339 hyperlipidemic rat model by Hussein, Buthaina, Alwahsh, Mohammad, Al-Hiari, Yusuf, Bourghli, Laurance, Al-Jammal, Basmah, Al-Qirim, Tareq, AlBujuq, Nader R., Abu-zaid, Rania, Saqallah, Fadi G., Hamadneh, Lama

Get full text

Unlocking the Conformational Changes of P2Y 12 : Exploring an Acridinone Compound's Effect on Receptor Activity and Conformation by Al-Najjar, Belal O, Saqallah, Fadi G

“…The P2Y receptor is an important member of the purinergic receptor family, known for its critical role in platelet activation and thrombosis. In our previously…”
Get full text

Antiproliferative Effects of Ajuga orientalis Methanolic Extract: In Vitro and In Silico Insights by Althaher, Arwa R., Saqallah, Fadi G., Qawass, Hala

“…Ajuga orientalis, a perennial herb from the Lamiaceae family, is traditionally used in Jordanian folk medicine for its therapeutic properties. This study…”
Get full text

P2Y 12 antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies by Al-Najjar, Belal O, Saqallah, Fadi G, Abbas, Manal A, Al-Hijazeen, Serena Z, Sibai, Obada A

“…P2Y is a platelet surface protein which is responsible for the amplification of P2Y response. It plays a crucial role in platelet aggregation and thrombus…”
Get full text

Carica papaya Leaf Extract Inhibits SARS-CoV-2 Main Proteases but not Human TMPRSS2: An In-vitro and In-silico Study by Hariono, Maywan, Hidayat, Irwan, Djunarko, Ipang, Julianus, Jeffry, Saqallah, Fadi G, Khawory, Muhammad Hidhir, Salin, Nurul Hanim, Wahab, Habibah Abdul

“…Carica papaya (CP) leaf is long known for its traditional pharmacological effects against dengue virus and malaria. Therefore, CP could also be a potential…”
Get full text