Search Results - "Sapuru, Vinay"

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  1. 1

    Structural titration reveals Ca2+-dependent conformational landscape of the IP3 receptor by Paknejad, Navid, Sapuru, Vinay, Hite, Richard K.

    Published in Nature communications (28-10-2023)
    “…Inositol 1,4,5-trisphosphate receptors (IP 3 Rs) are endoplasmic reticulum Ca 2+ channels whose biphasic dependence on cytosolic Ca 2+ gives rise to Ca 2+…”
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    Journal Article
  2. 2

    Membrane-mediated protein interactions drive membrane protein organization by Jiang, Yining, Thienpont, Batiste, Sapuru, Vinay, Hite, Richard K., Dittman, Jeremy S., Sturgis, James N., Scheuring, Simon

    Published in Nature communications (30-11-2022)
    “…The plasma membrane’s main constituents, i.e., phospholipids and membrane proteins, are known to be organized in lipid-protein functional domains and…”
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    Journal Article
  3. 3

    Discovery of Selective Inhibitors for the Lysosomal Parkinson’s Disease Channel TMEM175 by Oh, SeCheol, Lee, Jooyeon, Choi, Ho Jeong, Kim, Songwon, Sapuru, Vinay, Kim, Min, Hite, Richard K.

    Published in Journal of the American Chemical Society (21-08-2024)
    “…TMEM175 is a lysosomal potassium and proton channel that is associated with the development of Parkinson’s disease. Advances in understanding the physiological…”
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    Journal Article
  4. 4

    Structural titration reveals Ca 2+ -dependent conformational landscape of the IP 3 receptor by Paknejad, Navid, Sapuru, Vinay, Hite, Richard K

    Published in Nature communications (28-10-2023)
    “…Inositol 1,4,5-trisphosphate receptors (IP Rs) are endoplasmic reticulum Ca channels whose biphasic dependence on cytosolic Ca gives rise to Ca oscillations…”
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    Journal Article
  5. 5

    A pleiotropic recurrent dominant ITPR3 variant causes a complex multisystemic disease by Molitor, Anne, Lederle, Alexandre, Radosavljevic, Mirjana, Sapuru, Vinay, Zavorka Thomas, Megan E, Yang, Jianying, Shirin, Mahsa, Collin-Bund, Virginie, Jerabkova-Roda, Katerina, Miao, Zhichao, Bernard, Alice, Rolli, Véronique, Grenot, Pierre, Castro, Carla Noemi, Rosenzwajg, Michelle, Lewis, Elyssa G, Person, Richard, Esperón-Moldes, Uxía-Saraiva, Kaare, Milja, Nokelainen, Pekka T, Batzir, Nurit Assia, Hoffer, Gal Zaks, Paul, Nicodème, Stemmelen, Tristan, Naegely, Lydie, Hanauer, Antoine, Bibi-Triki, Sabrina, Grün, Sarah, Jung, Sophie, Busnelli, Ignacio, Tripolszki, Kornelia, Al-Ali, Ruslan, Ordonez, Natalia, Bauer, Peter, Song, Eunkyung, Zajo, Kristin, Partida-Sanchez, Santiago, Robledo-Avila, Frank, Kumanovics, Attila, Louzoun, Yoram, Hirschler, Aurélie, Pichot, Angélique, Toker, Ori, Mejía, Cesar Andrés Muñoz, Parvaneh, Nima, Knapp, Esther, Hersh, Joseph H, Kenney, Heather, Delmonte, Ottavia M, Notarangelo, Luigi D, Goetz, Jacky G, Kahwash, Samir B, Carapito, Christine, Bajwa, Rajinder P S, Thomas, Caroline, Ehl, Stephan, Isidor, Bertrand, Carapito, Raphael, Abraham, Roshini S, Hite, Richard K, Marcus, Nufar, Bertoli-Avella, Aida, Bahram, Seiamak

    Published in Science advances (13-09-2024)
    “…Inositol 1,4,5-trisphosphate (IP3) receptor type 1 ( ), ( ), and ( ) encode the IP3 receptor (IP3R), a key player in intracellular calcium release. In four…”
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    Journal Article