Search Results - "Sapru, Mohan K"

FDA Approval of Angiotensin II for the Treatment of Hypotension in Adults with Distributive Shock by Senatore, Fortunato, Jagadeesh, Gowraganahalli, Rose, Martin, Pillai, Venkateswaran C., Hariharan, Sudharshan, Liu, Ququan, Tzu-Yun, McDowell, Sapru, Mohan K., Southworth, Mary Ross, Stockbridge, Norman

“…Distributive shock is a subset of shock marked by decreased systemic vascular resistance, organ hypoperfusion and altered oxygen extraction. Despite the use of…”
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A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons by Han, Ye, Khodr, Christina E, Sapru, Mohan K, Pedapati, Jyothi, Bohn, Martha C

“…Abstract Alpha-synuclein (SNCA), an abundantly expressed presynaptic protein, is implicated in Parkinson's disease (PD). Since over-expression of human SNCA…”
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Silencing of human α-synuclein in vitro and in rat brain using lentiviral-mediated RNAi by Sapru, Mohan K., Yates, Jonathan W., Hogan, Shea, Jiang, Lixin, Halter, Jeremy, Bohn, Martha C.

“…Human α-synuclein overexpression and its toxic accumulation in neurons or glia are known to play key roles in the pathogenesis of Parkinson's disease and other…”
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Correction to: FDA Approval of Angiotensin II for the Treatment of Hypotension in Adults with Distributive Shock by Senatore, Fortunato, Jagadeesh, Gowraganahalli, Rose, Martin, Pillai, Venkateswaran C., Hariharan, Sudharshan, Liu, Ququan, McDowell, Tzu-Yun, Sapru, Mohan K., Southworth, Mary Ross, Stockbridge, Norman

“…The author name that previously read…”
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An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons by Khodr, Christina E, Sapru, Mohan K, Pedapati, Jyothi, Han, Ye, West, Neva C, Kells, Adrian P, Bankiewicz, Krystof S, Bohn, Martha C

“…Abstract Effects of silencing ectopically expressed hSNCA in rat substantia nigra (SN) were examined as a novel therapeutic approach to Parkinson's disease…”
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Identification of a Neuregulin and Protein-Tyrosine Phosphatase Response Element in the Nicotinic Acetylcholine Receptor ε Subunit Gene: Regulatory Role of an Ets Transcription Factor by Sapru, Mohan K., Florance, Sharon K., Kirk, Cassandra, Goldman, Daniel

“…At the neuromuscular synapse, innervation induces endplate-specific expression of adult-type nicotinic acetylcholine receptors by selective expression of their…”
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High-efficiency adenovirus-mediated in vivo gene transfer into neonatal and adult rodent skeletal muscle by Sapru, Mohan K, McCormick, Kathleen M, Thimmapaya, Bayer

“…Several methodological limitations have emerged in the use of viral gene transfer into skeletal muscle. First, because the nuclei of mature muscle fibers do…”
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Identification of a neuregulin and protein-tyrosine phosphatase response element in the nicotinic acetylcholine receptor ɛ subunit gene: Regulatory role of an Ets transcription factor by Sapru, Mohan K., Florance, Sharon K., Kirk, Cassandra, Goldman, Daniel

“…At the neuromuscular synapse, innervation induces endplate-specific expression of adult-type nicotinic acetylcholine receptors by selective expression of their…”
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944. Silencing of Endogenous Human á-Synuclein by a Lentiviral Vector Expressing Short Hairpin RNA by Sapru, Mohan K, Yates, Jonathan W, Bohn, Martha C

“…Synucleinopathies are a group of neurodegenerative disorders that include Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Current…”
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Molecular mechanisms mediating synapse-specific gene expression during development of the neuromuscular junction by Goldman, D, Sapru, M K

“…Adult skeletal muscle locally expresses nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction by selective induction of their…”
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Neuregulin-1 regulates expression of the Ets-2 transcription factor by Sapru, Mohan K.

“…At the neuromuscular synapse, synapse-specific gene expression is regulated by neuregulin, a motor neuron-derived factor, and involves participation of the…”
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Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle by Goldman, D, Sapru, M K, Stewart, S, Plotkin, J, Libermann, T A, Wasylyk, B, Guan, K

“…An Ets transcription factor family member, GETS-1, was cloned from a goldfish retina cDNA library. GETS-1 contains a conserved Ets DNA-binding domain at its…”
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Cloning and characterization of a novel transcriptional repressor of the nicotinic acetylcholine receptor delta-subunit gene by Sapru, M K, Gao, J P, Walke, W, Burmeister, M, Goldman, D

“…We have identified a negative cis-acting regulatory element in the nicotinic acetylcholine receptor delta-subunit gene's promoter. This element resides within…”
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Cloning and Characterization of a Novel Transcriptional Repressor of the Nicotinic Acetylcholine Receptor -Subunit Gene by Mohan K. Sapru, Jian Ping Gao, Wade Walke, Margit Burmeister, Daniel Goldman

“…We have identified a negative cis-acting regulatory element in the nicotinic acetylcholine receptor -subunit gene's promoter. This element resides within a…”
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Protein-tyrosine phosphatases specifically regulate muscle adult-type nicotinic acetylcholine receptor gene expression by Sapru, M K, Zhou, G, Goldman, D

“…Innervation of skeletal muscles results in expression of adult-type nicotinic acetylcholine receptors (alpha 2 beta epsilon delta) beneath the neuromuscular…”
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