Search Results - "Sappington, Penny"

Comparison of Anticoagulation Strategies in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation: Heparin Versus Bivalirudin by Rivosecchi, Ryan M., Arakelians, Aris R., Ryan, John, Murray, Holt, Ramanan, Raj, Gomez, Hernando, Phillips, Dennis, Sciortino, Christopher, Arlia, Peter, Freeman, Danielle, Sappington, Penny L., Sanchez, Pablo G.

“…Extracorporeal membrane oxygenation is a life-sustaining therapy for severe respiratory failure. Extracorporeal membrane oxygenation circuits require systemic…”
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Initial Experience With Single Cannulation for Venovenous Extracorporeal Oxygenation in Adults by Bermudez, Christian A., MD, Rocha, Rodolfo V., MD, Sappington, Penny L., MD, Toyoda, Yoshiya, MD, PhD, Murray, Holt N., MD, Boujoukos, Arthur J., MD

“…Purpose Historically, venovenous extracorporeal membrane oxygenation has required dual cannulation. A single-venous cannulation strategy may facilitate…”
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Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplant: Midterm Outcomes by Bermudez, Christian A., MD, Rocha, Rodolfo V., MD, Zaldonis, Diana, MPH, BSN, Bhama, Jay K., MD, Crespo, Maria M., MD, Shigemura, Norihisa, MD, PhD, Pilewski, Joseph M., MD, Sappington, Penny L., MD, Boujoukos, Arthur J., MD, Toyoda, Yoshiya, MD, PhD

“…Background Extracorporeal membrane oxygenation (ECMO) is used occasionally as a bridge to lung transplantation. The impact on mid-term survival is unknown. We…”
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Challenges in the development and implementation of a healthcare system based extracorporeal cardiopulmonary resuscitation (ECPR) program for the treatment of out of hospital cardiac arrest by Chonde, Meshe, Escajeda, Jeremiah, Elmer, Jonathan, Callaway, Clifton W., Guyette, Frank X., Boujoukos, Arthur, Sappington, Penny L., Smith, Anson J., Schmidhofer, Mark, Sciortino, Christopher, Kormos, Robert L.

“…Extracorporeal cardiopulmonary resuscitation (ECPR) can treat cardiac arrest refractory to conventional therapies. Many institutions are interested in…”
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Bivalirudin Versus Unfractionated Heparin in Patients With Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation by Uricchio, Marissa N., Ramanan, Raj, Esper, Stephen A., Murray, Holt, Kaczorowski, David J., D’Aloiso, Brandon, Gomez, Hernando, Sciortino, Christopher, Sanchez, Pablo G., Sappington, Penny L., Rivosecchi, Ryan M.

“…This study evaluated differences in efficacy and safety outcomes with bivalirudin compared with unfractionated heparin (UFH) in patients with cardiogenic shock…”
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Comparison of Hydromorphone versus Fentanyl‐based Sedation in Extracorporeal Membrane Oxygenation: A Propensity‐Matched Analysis by Landolf, Kaitlin M., Rivosecchi, Ryan M., Goméz, Hernando, Sciortino, Christopher M., Murray, Holt N., Padmanabhan, Rajagopala R., Sanchez, Pablo G., Harano, Takashi, Sappington, Penny L.

“…Introduction Data comparing sedatives in patients receiving extracorporeal membrane oxygenation (ECMO) are sparse. However, it is known that the ECMO circuit…”
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Extracorporeal Membrane Oxygenation for Advanced Refractory Shock in Acute and Chronic Cardiomyopathy by Bermudez, Christian A., MD, Rocha, Rodolfo V., MD, Toyoda, Yoshiya, MD, PhD, Zaldonis, Diana, MPH, BSN, Sappington, Penny L., MD, Mulukutla, Suresh, MD, Marroquin, Oscar C., MD, Toma, Catalin, MD, Bhama, Jay K., MD, Kormos, Robert L., MD

“…Background Extracorporeal membrane oxygenation (ECMO) has been used to obtain rapid resuscitation and stabilization in advanced refractory cardiogenic shock…”
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Oxygenated right ventricular assist device with a percutaneous dual-lumen cannula as a bridge to lung transplantation by Harano, Takashi, Chan, Ernest G, Furukawa, Masashi, Reck Dos Santos, Pedro, Morrell, Matthew R, Sappington, Penny L, Sanchez, Pablo G

“…Oxygenated right ventricular assist device (oxyRVAD) placement has become more streamlined with the introduction of the dual-lumen pulmonary artery cannula…”
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Extracorporeal membrane oxygenation support in acute coronary syndromes complicated by cardiogenic shock by Esper, Stephen A., Bermudez, Christian, Dueweke, Eric J., Kormos, Robert, Subramaniam, Kathirvel, Mulukutla, Suresh, Sappington, Penny, Waters, Jonathan, Khandhar, Sameer J.

“…Background Acute coronary syndrome (ACS) complicated by shock is associated with high mortality despite the use of percutaneous support devices. Extracorporeal…”
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HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice by Sappington, Penny L., Yang, Runkuan, Yang, Huan, Tracey, Kevin J., Delude, Russell L., Fink, Mitchell P.

“…Background & Aims: High mobility group (HMG) B1 is a nonhistone nuclear protein that was recently identified as a late-acting mediator of…”
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HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers by Liu, Shiguang, Stolz, Donna B, Sappington, Penny L, Macias, Carlos A, Killeen, Meaghan E, Tenhunen, Jyrki J, Delude, Russell L, Fink, Mitchell P

“…High-mobility group box 1 (HMGB1), a cytokine-like proinflammatory protein, is secreted by activated macrophages and released by necrotic cells. We…”
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The role of RAGE in the pathogenesis of intestinal barrier dysfunction after hemorrhagic shock by Raman, Kathleen G, Sappington, Penny L, Yang, Runkuan, Levy, Ryan M, Prince, Jose M, Liu, Shiguang, Watkins, Simon K, Schmidt, Ann Marie, Billiar, Timothy R, Fink, Mitchell P

“…The receptor for advanced glycation end products (RAGE) has been implicated in the pathogenesis of numerous conditions associated with excessive inflammation…”
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Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers by Sappington, Penny L, Han, Xiaonan, Yang, Runkuan, Delude, Russell L, Fink, Mitchell P

“…Ethyl pyruvate (EP) solution ameliorates ileal mucosal hyperpermeability and decreases the expression of several proinflammatory genes in ileal and/or colonic…”
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Isolation of Aspergillus in three 2009 H1N1 influenza patients by Adalja, Amesh A., Sappington, Penny L., Harris, Steven P., Rimmele, Thomas, Kreit, John W., Kellum, John A., Boujoukos, Arthur J.

“…Please cite this paper as: Adalja et al. (2011) Isolation of Aspergillus in three 2009 H1N1 influenza patients. Influenza and Other Respiratory Viruses 5(4),…”
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Ethyl pyruvate provides durable protection against inflammation-induced intestinal epithelial barrier dysfunction by SAPPINGTON, Penny L, FINK, Matthew E, RUNKUAN YANG, DELUDE, Russell L, FINK, Mitchell P

“…Ethyl pyruvate (EP) has been shown to be an effective anti-inflammatory agent. Herein, we sought to test the following hypotheses: 1) the pharmacological…”
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The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro by Sappington, Penny L., Cruz, Ruy J., Harada, Tomoyuki, Yang, Runkuan, Han, Yusheng, Englert, Joshua A., Ajami, Alfred A., Killeen, Meaghan E., Delude, Russell L., Fink, Mitchell P.

“…Ethyl pyruvate (EP) is a simple aliphatic ester derived from the endogenous metabolite, pyruvic acid. EP has been shown to decrease the expression of various…”
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Proinflammatory cytokines increase the rate of glycolysis and adenosine-5′-triphosphate turnover in cultured rat enterocytes by Berg, Sören, Sappington, Penny L, Guzik, Lynda J, Delude, Russell L, Fink, Mitchell P

“…OBJECTIVEMeasurements of steady-state adenosine-5′-triphosphate (ATP) levels in tissue samples from patients or experimental animals with sepsis or endotoxemia…”
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NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa by Han, Xiaonan, Uchiyama, Takashi, Sappington, Penny L, Yaguchi, Arino, Yang, Runkuan, Fink, Mitchell P, Delude, Russell L

“…In the course of other experiments, we serendipitously observed that extracellular nicotinamide adenine dinucleotide (NAD+) ameliorated the development of…”
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Cannulate, extubate, ambulate approach for extracorporeal membrane oxygenation for COVID-19 by Hayanga, J.W. Awori, Kakuturu, Jahnavi, Dhamija, Ankit, Asad, Fatima, McCarthy, Paul, Sappington, Penny, Badhwar, Vinay

“…We compared outcomes in patients with severe COVID-19 versus non–COVID-19-related acute respiratory distress syndrome (ARDS) managed using a dynamic,…”
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The Use of ECMO for the Treatment of Refractory Cardiac Arrest or Postarrest Cardiogenic Shock Following In-Hospital Cardiac Arrest: A 10-Year Experience by Chonde, Meshe, Sappington, Penny, Kormos, Robert, Althouse, Andrew, Boujoukos, Arthur

“…Objectives: Extracorporeal membrane oxygenation (ECMO) has been increasingly used in the treatment of refractory cardiac arrest (extracorporeal cardiopulmonary…”
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