Search Results - "Sapozhnikova, T A"
-
1
Synthesis of Glycyrrhizic Acid Conjugates with Amino-Acid Methyl Esters and their Ability to Stimulate Antibody Genesis in Mice
Published in Pharmaceutical chemistry journal (01-10-2022)“…Conjugates of glycyrrhizic acid (GA) with methyl esters of L -amino acids (valine, methionine, and glutamic acid) containing the amino-acid residues in the…”
Get full text
Journal Article -
2
Methylation of Quercetin by Diazomethane and Hypoglycemic Activity of its Tetra-O-Methyl Ether
Published in Chemistry of natural compounds (01-09-2020)“…The tetra- O -methyl ether of quercetin (QU) 3 (54%), 3,7,4′-tri- O -methyl ether 4 (30%), and a previously unreported 3,7,3-tri- O -methyl ether of QU 5 (7%)…”
Get full text
Journal Article -
3
Composition and Pharmacological Activity of Neutral Lipids from Rhizomes with Roots of the Introduced Plants Helleborus abchasicus and H. caucasicus
Published in Chemistry of natural compounds (01-11-2016)“…The compositions of neutral lipids (NL) and fatty acids (FA) from subterranean parts of the introduced plants Helleborus abchasicus and H. caucasicus…”
Get full text
Journal Article -
4
Transformation of Cloprostenol into E-Type Derivatives and a Comparative Study of Their Uterotonic Activity
Published in Pharmaceutical chemistry journal (01-04-2023)“…The racemic methyl ester of 16-( m -chlorophenoxy)-17,18,19,20-tetranorprostaglandin F 2α (cloprostenol) was transformed into corresponding E-type derivatives…”
Get full text
Journal Article -
5
Effects of novel hexahydropyrimidine derivatives as potential ligands of M1 muscarinic acetylcholine receptor on cognitive function, hypoxia-induced lethality, and oxidative stress in rodents
Published in Behavioural brain research (05-11-2019)“…The neurodegenerative diseases have a complex pathogenetic mechanism comprising oxidative stress and receptor system dysfunction caused by various damaging…”
Get full text
Journal Article -
6
Antiulcer Activity of 3-Hydroxyimino Derivatives of Minor Triterpenoids of Licorice Root
Published in Pharmaceutical chemistry journal (01-05-2022)“…3-Hydroxyimino derivatives of minor licorice triterpenoids possessed pronounced antiulcer activity and protected rat gastric mucosa from ulceration in…”
Get full text
Journal Article -
7
Synthesis and Hypoglycemic Activity of 2β,3β-Dihydroxy-18βH-Olean-12-EN-30-OIC Acid
Published in Chemistry of natural compounds (01-03-2020)Get full text
Journal Article -
8
Inclusion Complex of 11-deoxymisoprostol and Glycyrrhizic Acid with Improved Anti-Ulcer Activity
Published in Pharmaceutical chemistry journal (01-08-2022)“…A 1:4 inclusion complex of 11-deoxymisoprostol ( II ) with glycyrrhizic acid (complex III ) was synthesized and exhibited high anti-ulcer activity in…”
Get full text
Journal Article -
9
Hypoglycemic Activity of Glycyrrhizic Acid and Some of its Derivatives in the Alloxan Diabetes Model in Rats
Published in Pharmaceutical chemistry journal (01-07-2021)“…The hypoglycemic activity of glycyrrhizic acid (GA, I ), its trisodium ( II ) and sodium-dilithium salts ( III ), and a conjugate with L -methionine methyl…”
Get full text
Journal Article -
10
Synthesis and Anti-Inflammatory and Antiulcer Activity of a Glycyrrhizic Acid Conjugate with L-Phenylalanine Methyl Ester
Published in Pharmaceutical chemistry journal (01-06-2020)“…A conjugate of glycyrrhizic acid (GA) with L-phenylalanine methyl ester was synthesized using N -hydroxysuccinimide and…”
Get full text
Journal Article -
11
STUDY OF NOOTROPIC AND ANTI-HYPOXIC ACTIVITY OF 5-AMINO-3-EXO-AZATRICYCLO[5.2.1.02,6]DECAN-4-ON
Published in Razrabotka i registraciâ lekarstvennyh sredstv (Online) (14-02-2019)“…Introduction. Nootropic drugs are components of complex therapy for various neurological dysfunctions. One of the classes of ND are pyrrolidone derivatives,…”
Get full text
Journal Article -
12
Nootropic Activity of a Novel (-)-Cytisine Derivative (3aR,4S,8S,12R, 12aS,12bR)-10-Methyl-2-Phenyloctahydro-1H-4,12a-Etheno-8,12-Methanopyrrolo[3’,4’:3,4]Pyrido[1,2-a] [1,5]Diazocine-1,3,5(4H)-Trione
Published in Bulletin of experimental biology and medicine (01-03-2018)“…We performed screening of nootropic properties of 10 new derivatives of quinolizidine alkaloid (-)-cytisine. Compounds with β-endo stereochemistry were more…”
Get full text
Journal Article -
13
Hepatoprotective and Choleretic Properties of Levopimaric Acid Derivatives
Published in Pharmaceutical chemistry journal (01-08-2017)“…The hepatoprotective and choleretic activities of three levopimaric acid derivatives were studied experimentally using a CCl 4 -induced acute hepatitis model…”
Get full text
Journal Article -
14
THE STUDY OF THE PHARMACOKINETIC PROPERTIES OF 11-DEOXYMISOPROSTOL AFTER INTRAGASTRIC ADMINISTRATION
Published in Sechenovskiĭ vestnik (30-03-2019)“…The aim - to establish the main pharmacokinetic parameters of 11-deoxyimisoprostol after intragastric administration. Materials and methods. The experiments…”
Get full text
Journal Article -
15
New (−)−Cytisine Derivatives with Nootropic Activity
Published in Pharmaceutical chemistry journal (01-08-2015)“…The mnestic and antihypoxic effects of new derivatives of the quinolizidine alkaloid (−)-cytisine on acquisition of a conditioned passive avoidance reflex…”
Get full text
Journal Article -
16
Pharmacological Properties of Acetylsalicylic Acid and its Complex with Glycyrrhizic Acid as a Promising Dosage form (Review)
Published in Pharmaceutical chemistry journal (01-04-2024)“…The review summarizes current literature data on the mechanism of antithrombotic, anti-inflammatory, and antipyretic effects of acetylsalicylic acid (ASA),…”
Get full text
Journal Article -
17
Synthesis and Antiulcer Activity of Aromatic and Heterocyclic Amides of 3-O-Acetylglycyrrhetic Acid
Published in Pharmaceutical chemistry journal (01-02-2024)“…C30-amides of 3- O -acetylglycyrrhetic acid containing aromatic and heterocyclic pharmacophores were synthesized by the acid chloride method. The antiulcer…”
Get full text
Journal Article -
18
Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis
Published in Bulletin of experimental biology and medicine (01-02-2008)“…Therapeutic administration of 11-deoxymisoprostol had a hepatoprotective effect, which manifested in a decrease in the content of alanine transaminase and…”
Get full text
Journal Article -
19
Gastroprotective properties of 11-deoxymisoprostol (prostaglandin E1 analog) and its effect on the level of sialic acids in gastric tissue of rats with peptic ulcer
Published in Bulletin of experimental biology and medicine (01-10-2006)“…11-Deoxymisoprostol (prostaglandin E1 analog) exhibited a pronounced gastroprotective effect on various models of experimental ulcers induced by nonsteroid…”
Get full text
Journal Article -
20
Synthesis and Hypoglycemic Activity of 2[beta],3[beta]-Dihydroxy-18[beta]H-Olean-12-EN-30-OIC Acid
Published in Chemistry of natural compounds (01-03-2020)Get full text
Journal Article