Search Results - "Saporita, Anthony J."

ARF and p53 Coordinate Tumor Suppression of an Oncogenic IFN-β-STAT1-ISG15 Signaling Axis by Forys, Jason T., Kuzmicki, Catherine E., Saporita, Anthony J., Winkeler, Crystal L., Maggi, Leonard B., Weber, Jason D.

“…The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellular transformation in response to various oncogenic signals. Here, we…”
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The Hsp90 inhibitor, 17-AAG, prevents the ligand-independent nuclear localization of androgen receptor in refractory prostate cancer cells by Saporita, Anthony J., Ai, Junkui, Wang, Zhou

“…BACKGROUND Androgen receptor (AR) is the key molecule in androgen‐refractory prostate cancer. Despite androgen ablative conditions, AR remains active and is…”
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Hypergrowth mTORC1 Signals Translationally Activate the ARF Tumor Suppressor Checkpoint by Miceli, Alexander P., Saporita, Anthony J., Weber, Jason D.

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Identification and Characterization of a Ligand-regulated Nuclear Export Signal in Androgen Receptor by Saporita, Anthony J., Zhang, Qiuheng, Navai, Neema, Dincer, Zehra, Hahn, Junghyun, Cai, Xiaoyan, Wang, Zhou

“…Androgen receptor (AR) belongs to the steroid receptor superfamily that regulates gene expression in a ligand-dependent fashion. AR is localized to the…”
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p19ARF and RasV12 Offer Opposing Regulation of DHX33 Translation To Dictate Tumor Cell Fate by Zhang, Yandong, Saporita, Anthony J., Weber, Jason D.

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Therapeutic targets in the ARF tumor suppressor pathway by Saporita, Anthony J, Maggi, Jr, Leonard B, Apicelli, Anthony J, Weber, Jason D

“…One of the outstanding fundamental questions in cancer cell biology concerns how cells coordinate cellular growth (or macromolecular synthesis) with cell cycle…”
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Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers by Zhang, Yandong, Baysac, Kathleen C, Yee, Lian-Fai, Saporita, Anthony J, Weber, Jason D

“…The DDX21 RNA helicase has been shown to be a nucleolar and nuclear protein involved in ribosome RNA processing and AP-1 transcription. DDX21 is highly…”
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RNA Helicase DDX5 Is a p53-Independent Target of ARF That Participates in Ribosome Biogenesis by SAPORITA, Anthony J, CHANG, Hsiang-Chun, WINKELER, Crystal L, APICELLI, Anthony J, KLADNEY, Raleigh D, JIANBO WANG, REID TOWNSEND, R, MICHEL, Loren S, WEBER, Jason D

“…The p19ARF tumor suppressor limits ribosome biogenesis and responds to hyperproliferative signals to activate the p53 checkpoint response. Although its…”
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A Non-Tumor Suppressor Role for Basal p19ARF in Maintaining Nucleolar Structure and Function by Apicelli, Anthony J., Maggi, Leonard B., Hirbe, Angela C., Miceli, Alexander P., Olanich, Mary E., Schulte-Winkeler, Crystal L., Saporita, Anthony J., Kuchenreuther, Michael, Sanchez, José, Weilbaecher, Katherine, Weber, Jason D.

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Characterization of cytokine measurement in human serum, plasma, urine, tears, milk, CSF, and saliva with a MILLIPLEX® multiplex immunoassay by Steiner, Harold L, Luo, Hong, Ahmed, Tanzir, Gilliam, Brooke, Saporita, Anthony J, Qiang, Xiao

“…Multiplex immunoassays are valuable research tools for studying circulating cytokines. Here we evaluate the ability of the MILLIPLEX® Human…”
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Abstract 205: Analysis of resistance to RTK inhibitors using a novel RTK multiplex assay by Chen, Lu, Saporita, Anthony J., Lie, Wen-Rong, Maheshwari, Reeti, Schluter, Melissa, Mistry, Jehangir, Hwang, Joseph

“…A novel multiplex immunoassay was developed for examining acquired resistance to Receptor Tyrosine Kinase (RTK) inhibitors. RTKs are transmembrane proteins…”
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Abstract 4611: Interrogation of PI3K signaling via multiplex detection of differential phosphorylation of specific Akt isoforms by Saporita, Anthony J., Schluter, Melissa, MacIvor, Debra, Mistry, Jehangir, Hwang, Joseph

“…The serine/threonine protein kinase Akt is a key node in the PI3K pathway, one of the primary signaling cascades hyperactivated in human cancer. Emerging…”
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p19 ARF and Ras V12 Offer Opposing Regulation of DHX33 Translation To Dictate Tumor Cell Fate by Zhang, Yandong, Saporita, Anthony J., Weber, Jason D.

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The hsp90 inhibitor, 17-AAG, prevents the ligand-lndependent nuclear localization of androgen receptor in refractory prostate cancer cells by SAPORITA, Anthony J, JUNKUI AI, ZHOU WANG

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Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor by Saporita, Anthony J, Zhang, Qiuheng, Navai, Neema, Dincer, Zehra, Hahn, Junghyun, Cai, Xiaoyan, Wang, Zhou

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Natural Killer Cells Express Estrogen Receptor-α and Estrogen Receptor-β and Can Respond to Estrogen Via a Non-Estrogen Receptor-α-Mediated Pathway by Curran, Edward M., Berghaus, Londa J., Vernetti, Nicholas J., Saporita, Anthony J., Lubahn, Dennis B., Estes, D.Mark

“…Natural killer (NK) cells play a crucial role in host defense against pathogens and immune surveillance against cancer. Given that estrogens have been reported…”
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A Non-Tumor Suppressor Role for Basal p19 super(ARF) in Maintaining Nucleolar Structure and Function by Apicelli, Anthony J, Maggi, Leonard BJr, Hirbe, Angela C, Miceli, Alexander P, Olanich, Mary E, Schulte-Winkeler, Crystal L, Saporita, Anthony J, Kuchenreuther, Michael, Sanchez, Jose, Weilbaecher, Katherine, Weber, Jason D

“…The nucleolus is the center of ribosome synthesis, with the nucleophosmin (NPM) and p19 super(ARF) proteins antagonizing one another to either promote or…”
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Regulation of androgen receptor localization in prostate cancer cells by Saporita, Anthony J

“…The physiological consequences of androgen action are mediated by the androgen receptor (AR), a transcription factor that has instrumental roles in prostate…”
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A Non-Tumor Suppressor Role for Basal p19 ARF in Maintaining Nucleolar Structure and Function by Apicelli, Anthony J., Maggi, Leonard B., Hirbe, Angela C., Miceli, Alexander P., Olanich, Mary E., Schulte-Winkeler, Crystal L., Saporita, Anthony J., Kuchenreuther, Michael, Sanchez, José, Weilbaecher, Katherine, Weber, Jason D.

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