Search Results - "Sapkota, Kumar"
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1
FRET-Based Aptasensor for the Selective and Sensitive Detection of Lysozyme
Published in Sensors (Basel, Switzerland) (09-02-2020)“…Lysozyme is a conserved antimicrobial enzyme and has been cited for its role in immune modulation. Increase in lysozyme concentration in body fluids is also…”
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2
Single-Step FRET-Based Detection of Femtomoles DNA
Published in Sensors (Basel, Switzerland) (09-08-2019)“…Sensitive detection of nucleic acids and identification of single nucleotide polymorphism (SNP) is crucial in diagnosis of genetic diseases. Many strategies…”
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3
Chlorpyrifos and dichlorvos in combined exposure reveals antagonistic interaction to the freshwater fish Mrigal, Cirrhinus mrigala
Published in Ecotoxicology (London) (01-05-2022)“…Toxicity imposed by organophosphate pesticides to the freshwater cultivable fish species mrigal ( Cirrhinus mrigala ) was assessed under laboratory conditions…”
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4
Thrombolytic, anticoagulant and antiplatelet activities of codiase, a bi-functional fibrinolytic enzyme from Codium fragile
Published in Biochimie (01-06-2013)“…Thrombosis is a leading cause of morbidity and mortality throughout the world. Thrombolytic agents are important for both the prevention and treatment of…”
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5
Effects of invasive water hyacinth on fish diversity and abundance in the Lake Cluster of Pokhara Valley, Nepal
Published in Global ecology and conservation (01-10-2023)“…Water hyacinth (Pontederia crassipes) invasion is a growing global issue which poses a threat to aquatic life. As in the global context, the water hyacinth…”
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6
Rutin from Dendropanax morbifera Leveille Protects Human Dopaminergic Cells Against Rotenone Induced Cell Injury Through Inhibiting JNK and p38 MAPK Signaling
Published in Neurochemical research (01-04-2014)“…Dendropanax morbifera Leveille (Araliaceae) is well known in Korean traditional medicine for a variety of diseases. Rotenone is a commonly used neurotoxin to…”
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Assessment of Phytochemicals, Antioxidant Activity, Total Phenolic and Flavonoid Contents of Selected Nepalese Medicinal Plants
Published in Nepal journal of biotechnology (31-12-2022)“…Several medicinal plants have been used from the traditional period of times to cure different diseases but there is little scientific evidence. The…”
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Celastrol from ‘Thunder God Vine’ Protects SH-SY5Y Cells Through the Preservation of Mitochondrial Function and Inhibition of p38 MAPK in a Rotenone Model of Parkinson’s Disease
Published in Neurochemical research (01-01-2014)“…Celastrol, a potent natural triterpene and one of the most promising medicinal molecules, is known to possess a broad range of biological activity. Rotenone, a…”
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9
Bee (Hymenoptera: Apoidea) Fauna of Shivapuri-Nagarjun National Park, Nepal
Published in Journal of Asia-Pacific biodiversity (01-06-2022)“…The present study was carried out in Shivapuri-Nagarjun National Park to document the baseline data of bee fauna. The study was regulated at elevations of…”
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10
Antioxidant and Antimelanogenic Properties of Chestnut Flower Extract
Published in Bioscience, biotechnology, and biochemistry (2010)“…In this study, we analyzed the antioxidant and antimelanogenic properties of a variety of solvent extracts of pre-bloom and full-bloom chestnut flowers. Among…”
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11
Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: Purification and partial characterization
Published in Journal of bioscience and bioengineering (01-10-2014)“…A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase…”
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12
Build Your Own Microscope: Step-By-Step Guide for Building a Prism-Based TIRF Microscope
Published in Methods and protocols (03-11-2018)“…Prism-based total internal reflection fluorescence (pTIRF) microscopy is one of the most widely used techniques for the single molecule analysis of a vast…”
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13
Detoxified Extract of Rhus verniciflua Stokes Inhibits Rotenone-Induced Apoptosis in Human Dopaminergic Cells, SH-SY5Y
Published in Cellular and molecular neurobiology (01-03-2011)“…Rhus verniciflua Stokes (RVS), traditionally used as a food supplement and in traditional herbal medicine for centuries in Korea, is known to possess various…”
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Antioxidant Activity and Protective Effects of Tripterygium regelii Extract on Hydrogen Peroxide-Induced Injury in Human Dopaminergic Cells, SH-SY5Y
Published in Neurochemical research (01-08-2010)“…The present work was conducted to investigate the antioxidant activity and neuroprotective effects of Tripterygium regelii extract (TRE) on H 2 O 2 -induced…”
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15
Purification and characterization of a fibrinolytic enzyme from Petasites japonicus
Published in International journal of biological macromolecules (01-01-2015)“…A new, direct-acting chymotrypsin-like fibrinolytic serine protease was purified from Petasites japonicus, a medicinal herb. The molecular mass of the…”
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Purification and characterization of a novel, highly potent fibrinolytic enzyme from Paecilomyces tenuipes
Published in Process biochemistry (1991) (01-08-2011)“…A fibrinolytic enzyme (PTEFP) was purified from the entomopathogenic fungus Paecilomyces tenuipes. Analysis of the purified PTEFP by SDS–PAGE and fibrin…”
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Herinase: A Novel Bi-functional Fibrinolytic Protease from the Monkey Head Mushroom, Hericium erinaceum
Published in Applied biochemistry and biotechnology (01-06-2013)“…Herinase, a new bi-functional fibrinolytic metalloprotease, was purified from a medicinal and edible mushroom Hericium erinaceum . The enzyme was monomeric…”
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18
A Detoxified Extract of Rhus verniciflua Stokes Upregulated the Expression of BDNF and GDNF in the Rat Brain and the Human Dopaminergic Cell Line SH-SY5Y
Published in Bioscience, biotechnology, and biochemistry (2010)“…Rhus verniciflua Stokes (RVS) has traditionally been used as a food supplement and a traditional herbal medicine for centuries in Korea. This study attempted…”
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19
Direct acting anti-thrombotic serine protease from brown seaweed Costaria costata
Published in Process biochemistry (1991) (01-02-2013)“…► We report a new enzyme from Costaria costata, which was able to dissolve fibrin clot and human fibrinogen effectively. ► The ability of enzyme to induce…”
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Phytochemical Analysis and Antioxidant and Antidiabetic Activities of Extracts from Bergenia ciliata, Mimosa pudica, and Phyllanthus emblica
Published in Advances in pharmacological and pharmaceutical sciences (07-07-2022)“…Diabetes is a metabolic disorder of high blood sugar levels which leads to various chronic health-related complications. The digestive enzymes α-amylase and…”
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