Search Results - "Sapia, Ryan J."

Interrogation of highly structured RNA with multicomponent deoxyribozyme probes at ambient temperatures by Reed, Adam J, Sapia, Ryan J, Dowis, Charles, Solarez, Sheila, Gerasimova, Yulia V

“…Molecular analysis of RNA through hybridization with sequence-specific probes is challenging due to the intrinsic ability of RNA molecules to form stable…”
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Treatment of Organophosphorus Poisoning with 6‑Alkoxypyridin-3-ol Quinone Methide Precursors: Resurrection of Methylphosphonate-Aged Acetylcholinesterase by Clay, William K., Buck, Anne K., He, Yiran, Hernández Sánchez, Dalyanne N., Ward, Nathan A., Lear, Jeremy M., Nguyen, Kenny Q., Clark, Benjamin H., Sapia, Ryan J., Lalisse, Remy F., Sriraman, Aishwarya, Cadieux, C. Linn, McElroy, Craig A., Callam, Christopher S., Hadad, Christopher M.

“…Organophosphorus (OP) nerve agents inhibit acetylcholinesterase (AChE), creating a cholinergic crisis in which death can occur. The phosphylated serine residue…”
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Interaction of GelRed™ with single-stranded DNA oligonucleotides: Preferential binding to thymine-rich sequences by Sapia, Ryan J., Campbell, Colin, Reed, Adam J., Tsvetkov, Vladimir B., Gerasimova, Yulia V.

“…GelRed (GR) is a widely used nucleic acid-binding dye. It interacts with double-stranded DNA (dsDNA) via intercalation between the base-pairs, which enhances…”
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