Search Results - "Saparova, Valeria"

Comparability of biosimilar romiplostim with originator: Protein characterization, animal pharmacodynamics and pharmacokinetics by Arefeva, Anna N., Makarenko, Igor E., Saparova, Valeria B., Karal-ogli, Dzhina D., Afanaseva, Alina N., Dorotenko, Artem R., Kalatanova, Anna V., Kurkin, Denis V., Khokhlov, Alexandr L., Drai, Roman V.

“…The results of preclinical studies of romiplostim analogue GP40141 are presented. The effect of a cell proliferation, phosphorylation of the TPO receptor and…”
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A randomized, double‐blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers by Makarenko, Igor, Dorotenko, Artem, Noskov, Sergey, Banko, Veniamin, Saparova, Valeria, Khokhlov, Alexandr, Zoreeva, Evgeniia, Nedorubov, Andrey, Zinnatulina, Bella, Gefen, Maria, Drai, Roman

“…Abstract Aims The pharmacodynamic (PD) similarity between GP40141, a proposed romiplostim biosimilar, and reference romiplostim was evaluated. Pharmacokinetics…”
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Toxicity Patterns of Clinically Relevant Metal Oxide Nanoparticles by Fakhardo, Anna F, Anastasova, Elizaveta I, Gabdullina, Sabina R, Solovyeva, Anastasia S, Saparova, Valeria B, Chrishtop, Vladimir V, Koshevaya, Ekaterina D, Krivoshapkina, Elena F, Krivoshapkin, Pavel V, Kiselev, Grigorii O, Kalikina, Polina A, Koshel, Elena I, Shtil, Alexander A, Vinogradov, Vladimir V

“…Nanostructured drugs are being approved for clinical use, although there is a serious deficit of systematic studies of these materials. Data on toxicity of…”
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Population Pharmacokinetic and Pharmacodynamic Modeling of Romiplostim Biosimilar GP40141 and Reference Product in Healthy Volunteers to Evaluate Biosimilarity by Makarenko, Igor, Petrov, Aleksandr, Belova, Bella, Saparova, Valeria, Arefeva, Anna, Peskov, Kirill, Kudryashova, Nataliya, Khokhlov, Alexandr, Drai, Roman

“…GP40141 is a romiplostim biosimilar. A Phase 1 clinical trial was previously conducted in healthy volunteers to evaluate the pharmacodynamics (PD),…”
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Physiology, pharmacology and prospects for dipeptidilpeptidase-4 inhibitors use by Kurkin, D. V., Bakulin, D. A., Morkovin, E. I., Strygin, A. V., Gorbunova, Yu. V., Volotova, E. V., Makarenko, I. E., Saparova, V. B., Drai, R. V., Petrov, V. I.

“…Modern requirements for the treatment of type 2 diabetes mellitus (DM2) include not only achieving a glycemic control, but also reducing the risk of developing…”
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Фиксированные комбинации агонистов рецепторов ГПП-1 и базального инсулина: обзор литературы by Куркин, Д. В., Бакулин, Д. А., Морковин, Е. И., Стрыгин, А. В., Горбунова, Ю. В., Волотова, Е. В., Робертус, А. И., Макаренко, И. Е., Сапарова, В. Б., Драй, Р. В., Петров, В. И.

“…Прогрессирующее течение сахарного диабета 2 типа (СД2) приводит к необходимости назначения инсулинотерапии у значительной части больных. Как правило…”
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