Search Results - "Saori Otsuka-Kanazawa"

Age-related changes in bone morphology, function, and cell populations in inbred C57BL/6N mice by Takashi Namba, Osamu Ichii, Teppei Nakamura, Md.Abdul Masum, Yuki Otani, Saori Otsuka-Kanazawa, Yaser Hosny Ali Elewa, Yasuhiro Kon

“…[Abstract] Bones play crucial roles in controlling motility, regulating electrolyte metabolism, and hematopoiesis. We examined age-related changes in bone…”
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Morphological characteristics observed during early follicular development in perinatal MRL/MpJ mice by Yamashita, Yuma, Nakamura, Teppei, Otsuka-Kanazawa, Saori, Ichii, Osamu, Kon, Yasuhiro

“…[Abstract] In perinatal mice, the ovary undergoes drastic morphological changes, as clusters of oocytes called nests break into smaller cysts and subsequently…”
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Decreased miR-26a expression correlates with the progression of podocyte injury in autoimmune glomerulonephritis by Ichii, Osamu, Otsuka-Kanazawa, Saori, Horino, Taro, Kimura, Junpei, Nakamura, Teppei, Matsumoto, Manabu, Toi, Makoto, Kon, Yasuhiro

“…MicroRNAs contribute to the pathogenesis of certain diseases and may serve as biomarkers. We analyzed glomerular microRNA expression in B6.MRLc1, which serve…”
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Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand by Ichii, Osamu, Otsuka-Kanazawa, Saori, Nakamura, Teppei, Ueno, Masaaki, Kon, Yasuhiro, Chen, Weiping, Rosenberg, Avi Z, Kopp, Jeffrey B

“…Indoxyl sulfate is a uremic toxin and a ligand of the aryl-hydrocarbon receptor (AhR), a transcriptional regulator. Elevated serum indoxyl sulfate levels may…”
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Altered morpho-functional features of bones in autoimmune disease-prone BXSB/MpJ- Yaa mice by Namba, Takashi, Ichii, Osamu, Nakamura, Teppei, Masum, Md Abdul, Otani, Yuki, Otsuka-Kanazawa, Saori, Hosny Ali Elewa, Yaser, Kon, Yasuhiro

“…Bone disease, such as osteoporosis and rheumatoid arthritis, increases because of the progression of an aging society. Autoimmune disease are important and…”
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Asymmetric morphology of the cells comprising the inner and outer bending sides of the murine duodenojejunal flexure by Onouchi, Sawa, Ichii, Osamu, Otsuka-Kanazawa, Saori, Kon, Yasuhiro

“…The asymmetric shape of component cells determines the asymmetric features of developing organs. Here, we focused on the murine duodenojejunal flexure (DJF),…”
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Ovarian mast cells migrate toward ovary-fimbria connection in neonatal MRL/MpJ mice by Nakamura, Teppei, Chihara, Masataka, Ichii, Osamu, Otsuka-Kanazawa, Saori, Nagasaki, Ken-Ichi, Elewa, Yaser Hosny Ali, Tatsumi, Osamu, Kon, Yasuhiro

“…MRL/MpJ mice have abundant ovarian mast cells (MCs) as compared with other strains at postnatal day 0 (P0); however, they sharply decrease after birth. These…”
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Histopathological features of the proper gastric glands in FVB/N-background mice carrying constitutively-active aryl-hydrocarbon receptor by Dantsuka, Ai, Ichii, Osamu, Hanberg, Annika, Elewa, Yaser Hosny Ali, Otsuka-Kanazawa, Saori, Nakamura, Teppei, Kon, Yasuhiro

“…Aryl-hydrocarbon receptor (AhR) is a multiple ligand-activated transcription factor that has important roles in xenobiotic, physiological, or pathological…”
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Genomic analysis of the appearance of ovarian mast cells in neonatal MRL/MpJ mice by Nakamura, Teppei, Sakata, Yuko, Otsuka-Kanazawa, Saori, Ichii, Osamu, Chihara, Masataka, Nagasaki, Ken-ichi, Namiki, Yuka, Kon, Yasuhiro

“…In MRL/MpJ mice, ovarian mast cells (OMCs) are more abundant than in other mouse strains, and tend to distribute beneath the ovarian surface epithelium at…”
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Hydronephrosis with ureteritis developed in C57BL/6N mice carrying the congenic region derived from MRL/MpJ-type chromosome 11 by Ichii, Osamu, Chihara, Masataka, Lee, Shin-Hyo, Nakamura, Teppei, Otsuka-Kanazawa, Saori, Horino, Taro, Elewa, Yaser Hosny Ali, Kon, Yasuhiro

“…Inbred MRL/MpJ mice show several unique phenotypes in tissue regeneration processes and the urogenital and immune systems. Clarifying the genetic and molecular…”
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Testicular oocytes in MRL/MpJ mice possess similar morphological, genetic, and functional characteristics to ovarian oocytes by Otsuka-Kanazawa, Saori, Ichii, Osamu, Kon, Yasuhiro

“…•Newborn MRL/MpJ mice produce testicular oocytes.•Testicular oocytes are derived from XY germ cells that enter meiosis prematurely.•Fetal testicular oocytes…”
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Overexpression of Toll-like receptor 8 correlates with the progression of podocyte injury in murine autoimmune glomerulonephritis by Kimura, Junpei, Ichii, Osamu, Miyazono, Kosuke, Nakamura, Teppei, Horino, Taro, Otsuka-Kanazawa, Saori, Kon, Yasuhiro

“…Members of the Toll-like receptor (TLR) family serve as pathogen sensors and participate in local autoimmune responses. This study found a correlation between…”
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Feature Article: Altered morpho-functional features of bones in autoimmune disease-prone BXSB/MpJ-Yaa mice by Namba, Takashi, Ichii, Osamu, Nakamura, Teppei, Masum, Md Abdul, Otani, Yuki, Otsuka-Kanazawa, Saori, Hosny Ali Elewa, Yaser, Kon, Yasuhiro

“…Bones play crucial roles in motility, electrolyte metabolism, and immunity. Clinical cases have suggested bone dysfunction in several systemic autoimmune…”
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MRL/MpJ-Fas(lpr) mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease by Otani, Yuki, Ichii, Osamu, Otsuka-Kanazawa, Saori, Chihara, Masataka, Nakamura, Teppei, Kon, Yasuhiro

“…The immune system is known to affect reproductive function, and maternal-fetal immune tolerance is essential for a successful pregnancy. To investigate the…”
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MRL/MpJ mice produce more oocytes and exhibit impaired fertilisation and accelerated luteinisation after superovulation treatment by Hosotani, Marina, Ichii, Osamu, Nakamura, Teppei, Masum, Md Abdul, Otani, Yuki, Otsuka-Kanazawa, Saori, Elewa, Yaser H A, Kon, Yasuhiro

“…MRL/MpJ mice exhibit distinct phenotypes in several biological processes, including wound healing. Herein we report two unique phenotypes in the female…”
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Cotton rats (Sigmodon hispidus) possess pharyngeal pouch remnants originating from different primordia by Nakamura, Teppei, Ichii, Osamu, Irie, Takao, Mizoguchi, Tatsuya, Shinohara, Akio, Kouguchi, Hirokazu, Sunden, Yuji, Otsuka-Kanazawa, Saori, Ali Elewa, Yaser Hosny, Koshimoto, Chihiro, Nagasaki, Ken-Ichi, Kon, Yasuhiro

“…Pharyngeal pouches in mammals develop into specific derivatives. If the differentiation of the pharyngeal pouches is anomalous, their remnants can result in…”
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MRL/MpJ mice show unique pathological features after experimental kidney injury by Shiozuru, Daichi, Ichii, Osamu, Kimura, Junpei, Nakamura, Teppei, Elewa, Yaser Hosny Ali, Otsuka-Kanazawa, Saori, Kon, Yasuhiro

“…Clarification of the renal repair process is crucial for developing novel therapeutic strategies for kidney injury. MRL/MpJ mice have a unique repair process…”
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Degenerative and regenerative features of myofibers differ among skeletal muscles in a murine model of muscular dystrophy by Ikeda, Teppei, Ichii, Osamu, Otsuka-Kanazawa, Saori, Nakamura, Teppei, Elewa, Yaser Hosny Ali, Kon, Yasuhiro

“…Skeletal muscle myofibers constantly undergo degeneration and regeneration. Histopathological features of 6 skeletal muscles (cranial tibial [CT],…”
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MRL/MpJ- Fas lpr mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease by Otani, Yuki, Ichii, Osamu, Otsuka-Kanazawa, Saori, Chihara, Masataka, Nakamura, Teppei, Kon, Yasuhiro

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MRL/MpJ-Faslpr mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease by Otani, Yuki, Ichii, Osamu, Otsuka-Kanazawa, Saori, Chihara, Masataka, Nakamura, Teppei, Kon, Yasuhiro

“…The immune system is known to affect reproductive function, and maternal-fetal immune tolerance is essential for a successful pregnancy. To investigate the…”
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