Search Results - "Sanz Juste, Sara"

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    Next-generation CRISPR gene-drive systems using Cas12a nuclease by Sanz Juste, Sara, Okamoto, Emily M., Nguyen, Christina, Feng, Xuechun, López Del Amo, Víctor

    Published in Nature communications (12-10-2023)
    “…One method for reducing the impact of vector-borne diseases is through the use of CRISPR-based gene drives, which manipulate insect populations due to their…”
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    Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives by Xu, Xiang-Ru Shannon, Bulger, Emily A., Gantz, Valentino M., Klanseck, Carissa, Heimler, Stephanie R., Auradkar, Ankush, Bennett, Jared B., Miller, Lauren Ashley, Leahy, Sarah, Juste, Sara Sanz, Buchman, Anna, Akbari, Omar S., Marshall, John M., Bier, Ethan

    Published in Molecular cell (15-10-2020)
    “…CRISPR-Cas9-based gene drive systems possess the inherent capacity to spread progressively throughout target populations. Here we describe two self-copying (or…”
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    A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila by López Del Amo, Víctor, Juste, Sara Sanz, Gantz, Valentino M.

    Published in Cell reports (Cambridge) (24-05-2022)
    “…CRISPR-based gene-drives have been proposed for managing insect populations, including disease-transmitting mosquitoes, due to their ability to bias their…”
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    Cas9/Nickase-induced allelic conversion by homologous chromosome-templated repair in Drosophila somatic cells by Roy, Sitara, Juste, Sara Sanz, Sneider, Marketta, Auradkar, Ankush, Klanseck, Carissa, Li, Zhiqian, Julio, Alison Henrique Ferreira, Lopez del Amo, Victor, Bier, Ethan, Guichard, Annabel

    Published in Science advances (01-07-2022)
    “…Repair of double-strand breaks (DSBs) in somatic cells is primarily accomplished by error-prone nonhomologous end joining and less frequently by precise…”
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