Search Results - "Sanz, Ramón. García"

Genomic evolution of ibrutinib‐resistant clones in Waldenström macroglobulinaemia by Jiménez, Cristina, Chan, Gloria G., Xu, Lian, Tsakmaklis, Nickolas, Kofides, Amanda, Demos, Maria G., Chen, Jiaji, Liu, Xia, Munshi, Manit, Yang, Guang, Castillo, Jorge J., Wiestner, Adrian, García‐Sanz, Ramón, Treon, Steven P., Hunter, Zachary R.

“…Summary Ibrutinib is highly active in Waldenström macroglobulinaemia (WM) patients, but disease progression can occur due to acquired mutations in BTK, the…”
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6q deletion in Waldenström macroglobulinaemia negatively affects time to transformation and survival by García‐Sanz, Ramón, Dogliotti, Irene, Zaccaria, Gian Maria, Ocio, Enrique María, Rubio, Araceli, Murillo, Ilda, Escalante, Fernando, Aguilera, Carmen, García‐Mateo, Aránzazu, García de Coca, Alfonso, Hernández, Roberto, Dávila, Julio, Puig, Noemí, García‐Álvarez, María, Chillón, María del Carmen, Alcoceba, Miguel, Medina, Alejandro, González de la Calle, Verónica, Sarasquete, María Eugenia, González, Marcos, Gutiérrez, Norma Carmen, Jiménez, Cristina

“…Summary Deletion of the long arm of chromosome 6 (del6q) is the most frequent cytogenetic abnormality in Waldenström macroglobulinaemia (WM), occurring in…”
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FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma by Herrero, Ana Belén, Quwaider, Dalia, Corchete, Luis Antonio, Mateos, Maria Victoria, García‐Sanz, Ramón, Gutiérrez, Norma C.

“…FAM46C, frequently mutated in multiple myeloma (MM), has recently been shown to encode a non‐canonical poly(A) polymerase (ncPAP). However, its target mRNAs…”
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Liquid biopsy: a non‐invasive approach for Hodgkin lymphoma genotyping by Alcoceba, Miguel, García‐Álvarez, María, Chillón, M. Carmen, Jiménez, Cristina, Medina, Alejandro, Antón, Alicia, Blanco, Oscar, Díaz, Luis G., Tamayo, Pilar, González‐Calle, Verónica, Vidal, María Jesús, Cuello, Rebeca, Díaz Gálvez, Francisco Javier, Queizán, José Antonio, Martín, Alejandro, González, Marcos, García‐Sanz, Ramón, Sarasquete, M. Eugenia

“…Summary The Hodgkin lymphoma (HL) genomic landscape is hardly known due to the scarcity of tumour cells in the tissue. Liquid biopsy employing circulating…”
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Recovery of polyclonal immunoglobulins during treatment in patients ineligible for autologous stem‐cell transplantation is a prognostic marker of longer progression‐free survival and overall survival by Dávila, Julio, González‐Calle, Verónica, Escalante, Fernando, Cerdá, Seila, Puig, Noemí, García‐Sanz, Ramón, Bárez, Abelardo, Montes, Carmen, López, Rosa, Alonso, José María, Aguilar, Carlos, García‐Mateo, Aránzazu, Labrador, Jorge, Aguilera, Carmen, García‐Coca, Alfonso, Hernández, Roberto, Mateos, María‐Victoria, Ocio, Enrique M.

“…Summary Immunoparesis is the suppression of normal polyclonal immunoglobulins and is present in most patients with newly diagnosed multiple myeloma (MM). The…”
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Time to Move to the Single-Cell Level: Applications of Single-Cell Multi-Omics to Hematological Malignancies and Waldenström's Macroglobulinemia-A Particularly Heterogeneous Lymphoma by García-Sanz, Ramón, Jiménez, Cristina

“…Single-cell sequencing techniques have become a powerful tool for characterizing intra-tumor heterogeneity, which has been reflected in the increasing number…”
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Identification of the novel HLA‐A23:01:01:27 allele in an acute myeloid patient and related donor by Bastos, Miguel, Alcoceba, Miguel, Chillón, María Carmen, García‐Sanz, Ramón, Boix, Francisco

“…A single nucleotide polymorphism in intron 1 determines the new HLA‐A*23:01:01:27 allele…”
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Expression of p53 protein isoforms predicts survival in patients with multiple myeloma by Rojas, Elizabeta A., Corchete, Luis A., De Ramón, Cristina, Krzeminski, Patryk, Quwaider, Dalia, García‐Sanz, Ramón, Martínez‐López, Joaquín, Oriol, Albert, Rosiñol, Laura, Bladé, Joan, Lahuerta, Juan José, San Miguel, Jesús F., González, Marcos, Mateos, María Victoria, Bourdon, Jean‐Christophe, Misiewicz‐Krzeminska, Irena, Gutiérrez, Norma C.

“…Loss and/or mutation of the TP53 gene are associated with short survival in multiple myeloma, but the p53 landscape goes far beyond. At least 12 p53 protein…”
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Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease by Alcoceba, Miguel, Stewart, James P, García-Álvarez, María, Díaz, Luis G, Jiménez, Cristina, Medina, Alejandro, Chillón, M Carmen, Gazdova, Jana, Blanco, Oscar, Díaz, Francisco J, Peñarrubia, María J, Fernández, Silvia, Montes, Carlos, Cabero, Almudena, Caballero, María D, García-Sanz, Ramón, González, Marcos, González, David, Tamayo, Pilar, Gutiérrez, Norma C, García-Sancho, Alejandro Martín, Sarasquete, M Eugenia

“…Circulating tumour DNA (ctDNA) allows genotyping and minimal residual disease (MRD) detection in lymphomas. Using a next-generation sequencing (NGS) approach…”
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Identification of relapse‐associated gene mutations by next‐generation sequencing in low‐risk acute myeloid leukaemia patients by Prieto‐Conde, María Isabel, Jiménez, Cristina, García‐Álvarez, María, Ramos, Fernando, Medina, Alejandro, Cuello, Rebeca, Balanzategui, Ana, Alonso, José M., Sarasquete, Maria Eugenia, Queizán, José Antonio, Alcoceba, Miguel, Bárez, Abelardo, Puig, Noemí, Cantalapiedra, Alberto, Gutiérrez, Norma C., García‐Sanz, Ramón, González‐Díaz, Marcos, Chillón, María Carmen

“…Summary Recommended genetic categorization of acute myeloid leukaemias (AML) includes a favourable‐risk category, but not all these patients have good…”
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Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1‐acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group by Ocio, Enrique M., Motlló, Cristina, Rodríguez‐Otero, Paula, Martínez‐López, Joaquín, Cejalvo, Mª José, Martín‐Sánchez, Jesús, Bladé, Joan, García‐Malo, Mª Dolores, Dourdil, Mª Victoria, García‐Mateo, Aránzazu, Arriba, Felipe, García‐Sanz, Ramón, Rubia, Javier, Oriol, Albert, Lahuerta, Juan‐José, San‐Miguel, Jesús F., Mateos, María‐Victoria

“…Summary This phase I/II trial evaluated the combination of the kinesin spindle protein inhibitor filanesib with pomalidomide and dexamethasone in relapsed or…”
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Genomic landscape of follicular lymphoma across a wide spectrum of clinical behaviors by Mozas, Pablo, López, Cristina, Grau, Marta, Nadeu, Ferran, Clot, Guillem, Valle, Sara, Kulis, Marta, Navarro, Alba, Ramis-Zaldivar, Joan Enric, González-Farré, Blanca, Rivas-Delgado, Alfredo, Rivero, Andrea, Frigola, Gerard, Balagué, Olga, Giné, Eva, Delgado, Julio, Villamor, Neus, Matutes, Estella, Magnano, Laura, García-Sanz, Ramón, Huet, Sarah, Russell, Robert B, Campo, Elías, López-Guillermo, Armando, Beà, Sílvia

“…While some follicular lymphoma (FL) patients do not require treatment or experience prolonged responses, others relapse early, and little is known about…”
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Immunoparesis in IgM gammopathies as a useful biomarker to predict disease progression by Andrade-Campos, Marcio, Murillo-Flórez, Ilda, García-Sanz, Ramón, Giraldo, Pilar

“…The management of IgM monoclonal gammopathies undetermined significance (IgM-MGUS) and Waldenstrom's macroglobulinemia (WM) may be challenging. Modern…”
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Zebularine-induced myeloma cell death is accompanied by decreased c-Myc expression by Krzeminski, Patryk, García-Sanz, Ramón, Gutiérrez, Norma C.

“…Purpose Epigenetic therapies have proven to be clinically effective in several hematological malignancies. Here, we aimed to evaluate the effect of a…”
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Ponalfil trial for adults with Philadelphia chromosome‐positive acute lymphoblastic leukemia: Long‐term results by Ribera, Josep‐Maria, Morgades, Mireia, Ribera, Jordi, Montesinos, Pau, Cano‐Ferri, Isabel, Martínez, Pilar, Esteve, Jordi, Esteban, Daniel, García‐Fortes, María, Alonso, Natalia, González‐Campos, José, Bermúdez, Arancha, Torrent, Anna, Genescà, Eulàlia, Maluquer, Clara, Martínez‐López, Joaquín, García‐Sanz, Ramón

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Phase II trial of ofatumumab plus ESHAP (O‐ESHAP) as salvage treatment for patients with relapsed or refractory classical Hodgkin lymphoma after first‐line chemotherapy by Martínez, Carmen, Díaz‐López, Antonio, Rodriguez‐Calvillo, Mercedes, García‐Sanz, Ramón, Terol, María José, Pérez‐Ceballos, Elena, Jiménez, Maria J., Cantalapiedra, Alberto, Domingo‐Domenech, Eva, Rodriguez, María José, Sampol, Antonia, Espeso, Manuel, López, Francisco‐Javier, Briones, Javier, García, Juan F., Sureda, Anna

“…Summary The management of recurrent/refractory (R/R) Hodgkin lymphoma (HL) remains challenging. Previously published data have shown some efficacy of rituximab…”
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P1679: HEALTH‐RELATED QUALITY OF LIFE IN PATIENTS (PTS) WITH WALDENSTRÖM MACROGLOBULINEMIA (WM) TREATED WITH ZANUBRUTINIB (ZANU) VS IBRUTINIB (IBR): RESULTS FROM THE PHASE 3 ASPEN TRIAL LONG‐TERM FOLLOW‐UP by Tedeschi, Alessandra, Tam, Constantine, Owen, Roger, Buske, Christian, Leblond, Véronique, Dimopoulos, Meletios A., García‐Sanz, Ramón, Castillo, Jorge, Trotman, Judith, Treon, Steven, Yang, Keri, Tang, Boxiong, Allewelt, Heather, Patel, Sheel, Chan, Wai, Cohen, Aileen, Schneider, Jingjing Yan, Barnes, Gisoo

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Exportin‐1 E571K mutation is a common finding in patients with classical Hodgkin lymphoma by Navarro‐Bailón, Almudena, Jiménez, Cristina, Alonso‐Álvarez, Sara, Alcoceba, Miguel, González‐Calle, Verónica, Chillón, María Carmen, García‐Álvarez, María, Prieto, Isabel, Medina, Alejandro, González, Marcos, Caballero, María Dolores, Blanco, Óscar, Díaz, Luis Gonzaga, García‐Sanz, Ramón, Sarasquete, María Eugenia

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Identification of miRSNPs associated with the risk of multiple myeloma by Macauda, Angelica, Calvetti, Diego, Maccari, Giuseppe, Hemminki, Kari, Försti, Asta, Goldschmidt, Hartmut, Weinhold, Niels, Houlston, Richard, Andersen, Vibeke, Vogel, Ulla, Buda, Gabriele, Varkonyi, Judit, Sureda, Anna, Martinez Lopez, Joaquin, Watek, Marzena, Butrym, Aleksandra, Sarasquete, Maria Eugenia, Dudziński, Marek, Jurczyszyn, Artur, Druzd‐Sitek, Agnieszka, Kruszewski, Marcin, Subocz, Edyta, Petrini, Mario, Iskierka‐Jażdżewska, Elzbieta, Raźny, Malgorzata, Szombath, Gergely, Marques, Herlander, Zawirska, Daria, Chraniuk, Dominik, Halka, Janusz, Hove Jacobsen, Svend Erik, Mazur, Grzegorz, García Sanz, Ramón, Dumontet, Charles, Moreno, Victor, Stępień, Anna, Beider, Katia, Pelosini, Matteo, Manuel Reis, Rui, Krawczyk‐Kulis, Malgorzata, Rymko, Marcin, Avet‐Loiseau, Hervé, Lesueur, Fabienne, Grząśko, Norbert, Ostrovsky, Olga, Jamroziak, Krzysztof, Vangsted, Annette J., Jerez, Andrés, Tomczak, Waldemar, Zaucha, Jan Maciej, Kadar, Katalin, Sainz, Juan, Nagler, Arnon, Landi, Stefano, Gemignani, Federica, Canzian, Federico

“…Multiple myeloma (MM) is a malignancy of plasma cells usually infiltrating the bone marrow, associated with the production of a monoclonal immunoglobulin (M…”
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The combination of bortezomib and dexamethasone is an efficient therapy for relapsed/refractory scleromyxedema: a rare disease with new clinical insights by Cañueto, Javier, Labrador, Jorge, Román, Concepción, Santos‐Briz, Ángel, Contreras, Teresa, Gutiérrez, Norma Carmen, García‐Sanz, Ramón

“…Scleromyxedema (SM) is a rare primary cutaneous inflammatory mucinosis characterised by papular mucinosis, monoclonal gammopathy and extracutaneous…”
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