Search Results - "Sanvicente, Adrian"

Clinical and Immunologic Characteristics of Colorectal Cancer Tumors Expressing LY6G6D by Sanvicente García, Adrián, Pedregal, Manuel, Paniagua-Herranz, Lucía, Díaz-Tejeiro, Cristina, Nieto-Jiménez, Cristina, Pérez Segura, Pedro, Munkácsy, Gyöngyi, Győrffy, Balázs, Calvo, Emiliano, Moreno, Víctor, Ocaña, Alberto

“…The identification of targets that are expressed on the cell membrane is a main goal in cancer research. The Lymphocyte Antigen 6 Family Member G6D ( ) gene…”
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An Immunological Approach to the Biocompatibility of Mesoporous SiO2-CaO Nanospheres by Montes-Casado, María, Sanvicente, Adrian, Casarrubios, Laura, Feito, María José, Rojo, José M., Vallet-Regí, María, Arcos, Daniel, Portolés, Pilar, Portolés, María Teresa

“…Mesoporous bioactive glass nanospheres (NanoMBGs) have high potential for clinical applications. However, the impact of these nanoparticles on the immune…”
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Overcoming limitations for antibody-based therapies targeting γδ T (Vg9Vd2) cells by Paniagua-Herranz, Lucía, Díaz-Tejeiro, Cristina, Sanvicente, Adrián, Bartolomé, Jorge, Nieto-Jiménez, Cristina, Ocana, Alberto

“…Therapeutic strategies targeting non-adaptive immune cells are currently in clinical development. γδT cells are a small subtype of T cells (1-10% of total T…”
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In Silico Transcriptomic Expression of MSR1 in Solid Tumors Is Associated with Responses to Anti-PD1 and Anti-CTLA4 Therapies by Sanvicente, Adrián, Díaz-Tejeiro, Cristina, Nieto-Jiménez, Cristina, Paniagua-Herranz, Lucia, López Cade, Igor, Balázs, Győrffy, Moreno, Víctor, Pérez-Segura, Pedro, Calvo, Emiliano, Ocaña, Alberto

“…Immuno-oncology has gained momentum with the approval of antibodies with clinical activities in different indications. Unfortunately, for anti-PD (L)1 agents…”
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Considerations for the design of antibody drug conjugates (ADCs) for clinical development: lessons learned by López de Sá, Alfonso, Díaz-Tejeiro, Cristina, Poyatos-Racionero, Elisa, Nieto-Jiménez, Cristina, Paniagua-Herranz, Lucía, Sanvicente, Adrián, Calvo, Emiliano, Pérez-Segura, Pedro, Moreno, Víctor, Moris, Francisco, Ocana, Alberto

“…Antibody-drug conjugates (ADCs) have emerged as a novel therapeutic strategy that has successfully reached patient treatment in different clinical scenarios…”
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Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2 by Paniagua-Herranz, Lucía, Moreno, Irene, Nieto-Jiménez, Cristina, Garcia-Lorenzo, Esther, Díaz-Tejeiro, Cristina, Sanvicente, Adrián, Doger, Bernard, Pedregal, Manuel, Ramón, Jorge, Bartolomé, Jorge, Manzano, Arancha, Gyorffy, Balázs, Gutierrez-Uzquiza, Álvaro, Pérez Segura, Pedro, Calvo, Emiliano, Moreno, Víctor, Ocana, Alberto

“…The identification of surfaceome proteins is a main goal in cancer research to design antibody-based therapeutic strategies. T cell engagers based on KLK2, a…”
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Antitumoral activity of a CDK12 inhibitor in colorectal cancer through a liposomal formulation by Díaz-Tejeiro, Cristina, Arenas-Moreira, María, Sanvicente, Adrián, Paniagua-Herranz, Lucía, Clemente-Casares, Pilar, Bravo, Ivan, Alonso-Moreno, Carlos, Nieto-Jiménez, Cristina, Ocaña, Alberto

“…Colorectal cancer (CRC) is the third most common cancer worldwide. Recent experiments suggest that CDK12 can be a good therapeutic target in CRC, and…”
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Effective Actions of Ion Release from Mesoporous Bioactive Glass and Macrophage Mediators on the Differentiation of Osteoprogenitor and Endothelial Progenitor Cells by Polo-Montalvo, Alberto, Casarrubios, Laura, Serrano, María Concepción, Sanvicente, Adrián, Feito, María José, Arcos, Daniel, Portolés, María Teresa

“…Due to their specific mesoporous structure and large surface area, mesoporous bioactive glasses (MBGs) possess both drug-delivery ability and effective ionic…”
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Genomic mapping of copy number variations influencing immune response in breast cancer by López-Cade, Igor, García-Barberán, Vanesa, Cabañas Morafraile, Esther, Díaz-Tejeiro, Cristina, Saiz-Ladera, Cristina, Sanvicente, Adrián, Pérez Segura, Pedro, Pandiella, Atanasio, Győrffy, Balázs, Ocaña, Alberto

“…Identification of genomic alterations that influence the immune response within the tumor microenvironment is mandatory in order to identify druggable…”
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Uncovering therapeutic opportunities in the clinical development of antibody‐drug conjugates by Nieto‐Jiménez, Cristina, Sanvicente, Adrián, Díaz‐Tejeiro, Cristina, Moreno, Víctor, lopez de Sá, Alfonso, Calvo, Emiliano, Martínez‐López, Joaquín, Pérez‐Segura, Pedro, Ocaña, Alberto

“…Abstract Introduction Antibody‐drug conjugates (ADCs) are a family of therapeutic agents that have demonstrated clinical activity in several indications…”
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Genomic Mapping of Epidermal Growth Factor Receptor and Mesenchymal-Epithelial Transition-Up-Regulated Tumors Identifies Novel Therapeutic Opportunities by Paniagua-Herranz, Lucía, Doger, Bernard, Díaz-Tejeiro, Cristina, Sanvicente, Adrián, Nieto-Jiménez, Cristina, Moreno, Víctor, Pérez Segura, Pedro, Gyorffy, Balazs, Calvo, Emiliano, Ocana, Alberto

“…The identification of proteins in the cellular membrane of the tumoral cell is a key to the design of therapeutic agents. Recently, the bi-specific antibody…”
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An Immunological Approach to the Biocompatibility of Mesoporous SiO 2 -CaO Nanospheres by Montes-Casado, María, Sanvicente, Adrian, Casarrubios, Laura, Feito, María José, Rojo, José M, Vallet-Regí, María, Arcos, Daniel, Portolés, Pilar, Portolés, María Teresa

“…Mesoporous bioactive glass nanospheres (NanoMBGs) have high potential for clinical applications. However, the impact of these nanoparticles on the immune…”
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Association of encapsulation of CDK12 inhibitor with anti-tumour activity in colon cancer cell lines by Pérez-Segura, Pedro, Diaz-Tejeiro, Cristina, Ocana, Alberto, Sanvicente, Adrián, Arenas-Moreira, María, Moreno, Carlos Alonso, Nieto Jiménez, Cristina

“…e15077 Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Unfortunately, despite the incorporation of new therapeutic options, the…”
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