Search Results - "Santrač Anja"

Vasodilatory effects of a variety of positive allosteric modulators of GABAA receptors on rat thoracic aorta by Bojić, Milica Gajić, Todorović, Lidija, Santrač, Anja, Mian, Md Yeunus, Sharmin, Dishary, Cook, James M., Savić, Miroslav M.

“…•Expression of GABAA receptor subunits on blood vessels is mainly unknown.•We showed the expression of α1, α2, α3, α4 and α5 subunits in the rat thoracic…”
Get full text

Parenteral nanoemulsions of risperidone for enhanced brain delivery in acute psychosis: Physicochemical and in vivo performances by Đorđević, Sanela M., Santrač, Anja, Cekić, Nebojša D., Marković, Bojan D., Divović, Branka, Ilić, Tanja M., Savić, Miroslav M., Savić, Snežana D.

“…[Display omitted] This work aimed to deepen the lately acquired knowledge about parenteral nanoemulsions as carriers for brain delivery of risperidone, a…”
Get full text

Lipopolysaccharide exposure during late embryogenesis results in diminished locomotor activity and amphetamine response in females and spatial cognition impairment in males in adult, but not adolescent rat offspring by Batinic, Bojan, Santrac, Anja, Divovic, Branka, Timic, Tamara, Stankovic, Tamara, Obradovic, Aleksandar Lj, Joksimovic, Sran, Savic, Miroslav M

“…[Display omitted] •Effects of LPS applied in late embryogenesis were tested at postnatal days 40 and 60.•Male rats exhibited spatial learning and memory…”
Get full text

Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease by Aranđelović, Jovana, Santrač, Anja, Batinić, Bojan, Todorović, Lidija, Stevanović, Vladimir, Tiruveedhula, Veera Venkata Naga Phani Babu, Sharmin, Dishary, Rashid, Farjana, Stanojević, Boban, Cook, James M., Savić, Miroslav M.

“…Aims GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD,…”
Get full text

SYSTEMIC INFLAMMATION FOLLOWED BY CHRONIC UNPREDICTABLE STRESS IN RATS: THE MODEL OF “BINGE-DRINKING” OF SUCROSE SOLUTION by Aranđelović, Jovana, Kojić, Jana, Batinić, Bojan, Matović, Branka Divović, Mirković, Kristina, Santrač, Anja, Savić, Miroslav

Get full text

Real-time PCR and immunocytochemical study of chondroitin sulfate proteoglycans after scratch wounding in cultured astrocytes by Parabucki Ana, Santrač Anja, Savić Danijela, Dacić Sanja, Bjelobaba Ivana, Peković Sanja, Stojiljković Mirjana

“…Background: Various in vivo and in vitro models have been described in order to elucidate the pathobiology underlying the traumatic brain injury (TBI) and test…”
Get full text

Real-Time PCR and Immunocytochemical Study of Chondroitin Sulfate Proteoglycans after Scratch Wounding in Cultured Astrocytes / PCR I IMUNOCITOHEMIJSKA STUDIJA EKSPRESIJE HONDROITIN-SULFATNIH PROTEOGLIKANA NAKON POVREDE ASTROCITA U KULTURI by Parabucki, Ana, Santrač, Anja, Savić, Danijela, Dacić, Sanja, Bjelobaba, Ivana, Peković, Sanja, Stojiljković, Mirjana

“…Various in vivo and in vitro models have been described in order to elucidate the pathobiology underlying the traumatic brain injury (TBI) and test potentially…”
Get full text

Positive modulation of α5GABAA receptors leads to dichotomous effects in rats on memory pattern and GABRA5 expression in prefrontal cortex and hippocampus by Santrač, Anja, Batinić, Bojan, Stamenić, Tamara Timić, Aranđelović, Jovana, Sharmin, Dishary, Knutson, Daniel E., Cook, James M., Savić, Miroslav M.

“…Positive allosteric modulators (PAMs) of α5GABAA receptors (α5GABAARs) are emerging as potential therapeutics for a range of neuropsychiatric disorders…”
Get full text

Postweaning positive modulation of α5GABAA receptors improves autism‐like features in prenatal valproate rat model in a sex‐specific manner by Santrač, Anja, Bijelić, Dunja, Stevanović, Vladimir, Banićević, Marija, Aranđelović, Jovana, Batinić, Bojan, Sharmin, Dishary, Cook, James M., Savić, Miroslav M.

“…Autism spectrum disorder (ASD), as a common neurodevelopmental disorder that encompasses impairments in social communication and interaction, as well as…”
Get full text

Positive and Negative Selective Allosteric Modulators of α5 GABAA Receptors: Effects on Emotionality, Motivation, and Motor Function in the 5xFAD Model of Alzheimer's Disease by Aranđelović, Jovana, Santrač, Anja, Batinić, Bojan, Todorović, Lidija, Ahmed Khan, Md Zubair, Rashid, Farjana, Poe, Michael M, Obradović, Aleksandar, Cook, James M, Savić, Miroslav M

“…Positive and negative allosteric modulators of α5 GABAA receptors (PAM and NAM, respectively) are worthy of investigation as putative treatments of Alzheimer's…”
Get more information

Effects of α5 GABA A receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease by Aranđelović, Jovana, Santrač, Anja, Batinić, Bojan, Todorović, Lidija, Stevanović, Vladimir, Tiruveedhula, Veera Venkata Naga Phani Babu, Sharmin, Dishary, Rashid, Farjana, Stanojević, Boban, Cook, James M, Savić, Miroslav M

“…GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we…”
Get full text

Positive modulation of α5 GABAA receptors in preadolescence prevents reduced locomotor response to amphetamine in adult female but not male rats prenatally exposed to lipopolysaccharide by Batinić, Bojan, Santrač, Anja, Jančić, Ivan, Li, Guanguan, Vidojević, Aleksandra, Marković, Bojan, Cook, James M., Savić, Miroslav M.

“…[Display omitted] •In utero exposure to 100μg/kg LPS at E15/16 changes behavior in rat adulthood.•Maternal immune activation results in GABA/glutamate…”
Get full text

Vasodilatory effects of a variety of positive allosteric modulators of GABA A receptors on rat thoracic aorta by Bojić, Milica Gajić, Todorović, Lidija, Santrač, Anja, Mian, Md Yeunus, Sharmin, Dishary, Cook, James M, Savić, Miroslav M

“…Different subtypes of GABA (gamma-aminobutyric acid A) receptors, through their specific regional and cellular localization, are involved in the manifestation…”
Get full text

Positive modulation of α5 GABA A receptors in preadolescence prevents reduced locomotor response to amphetamine in adult female but not male rats prenatally exposed to lipopolysaccharide by Batinić, Bojan, Santrač, Anja, Jančić, Ivan, Li, Guanguan, Vidojević, Aleksandra, Marković, Bojan, Cook, James M, Savić, Miroslav M

“…We previously demonstrated that lipopolysaccharide (LPS) administered intraperitoneally (i.p.) to pregnant Wistar rat dams, at embryonic days 15 and 16…”
Get full text

Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit by Stamenić, Tamara Timić, Poe, Michael M., Rehman, Sabah, Santrač, Anja, Divović, Branka, Scholze, Petra, Ernst, Margot, Cook, James M., Savić, Miroslav M.

“…We have synthesized and characterized MP-III-022 ((R)−8-ethynyl-6-(2-fluorophenyl)-N,4-dimethyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide) in vitro…”
Get full text

Uticaj Pozitivne Modulacije Gabaa Receptora Koji Sadrže Alfa5 Podjedinicu na Promene Ponašanja Miševa i Pacova u Modelima Autističnih Poremećaja by Santrač, Anja S

“…Dobro je poznata uloga α5 GABAA receptora u učenju i pamćenju. Zato smo odlučili da ispitamo efekat selektivnog pozitivnog alosternog modulatora (PAM),…”
Get full text

Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABA A receptors containing the α5 subunit by Stamenić, Tamara Timić, Poe, Michael M, Rehman, Sabah, Santrač, Anja, Divović, Branka, Scholze, Petra, Ernst, Margot, Cook, James M, Savić, Miroslav M

“…We have synthesized and characterized MP-III-022 ((R)-8-ethynyl-6-(2-fluorophenyl)-N,4-dimethyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide) in vitro…”
Get full text

S162. Antidepressant and Pro-Cognitive Effects of a Novel Series of GABA-A Receptor Positive Allosteric Modulators With α5 Subunit Efficacy Properties by Prevot, Thomas, Li, Guanguan, Vidojevic, Aleksandra, Santrac, Anja, Misquitta, Keith, Hu, Xiyue, Knutson, Daniel, Arnold, Leggi, Fisher, Janet, Banasr, Mounira, Cook, Jim, Savic, Miroslav, Sibille, Etienne

Get full text

Positive modulation of a5 GABA^sub A^ receptors in preadolescence prevents reduced locomotor response to amphetamine in adult female but not male rats prenatally exposed to lipopolysaccharide by Batinic, Bojan, Santrac, Anja, Jancic, Ivan, Li, Guanguan, Vidojevic, Aleksandra, Markovic, Bojan, Cook, James M, Savic, Miroslav M

“…We previously demonstrated that lipopolysaccharide (LPS) administered intraperitoneally (i.p.) to pregnant Wistar rat dams, at embryonic days 15 and 16…”
Get full text

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles by Prevot, Thomas D, Li, Guanguan, Vidojevic, Aleksandra, Misquitta, Keith A, Fee, Corey, Santrac, Anja, Knutson, Daniel E, Stephen, Michael Rajesh, Kodali, Revathi, Zahn, Nicolas M, Arnold, Leggy A, Scholze, Petra, Fisher, Janet L, Marković, Bojan D, Banasr, Mounira, Cook, James M, Savic, Miroslav, Sibille, Etienne

“…Altered gamma-aminobutyric acid (GABA) function is consistently reported in psychiatric disorders, normal aging, and neurodegenerative disorders and reduced…”
Get full text