Search Results - "Santostefano, Katherine E."

  • Showing 1 - 18 results of 18
Refine Results
  1. 1

    Concise Review: Induced Pluripotent Stem Cell Research in the Era of Precision Medicine by Hamazaki, Takashi, El Rouby, Nihal, Fredette, Natalie C., Santostefano, Katherine E., Terada, Naohiro

    Published in Stem cells (Dayton, Ohio) (01-03-2017)
    “…Recent advances in DNA sequencing technologies are revealing how human genetic variations associate with differential health risks, disease susceptibilities,…”
    Get full text
    Journal Article
  2. 2

    CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV‐1 infection in macrophages by Taylor, Jared P., Cash, Melanie N., Santostefano, Katherine E., Nakanishi, Mahito, Terada, Naohiro, Wallet, Mark A.

    Published in Journal of leukocyte biology (13-02-2018)
    “…The IFN‐stimulated gene ubiquitin‐specific proteinase 18 (USP18) encodes a protein that negatively regulates T1 IFN signaling via stearic inhibition of JAK1…”
    Get full text
    Journal Article
  3. 3

    Selective serotonin reuptake inhibitors ameliorate MEGF10 myopathy by Saha, Madhurima, Rizzo, Skylar A, Ramanathan, Manashwi, Hightower, Rylie M, Santostefano, Katherine E, Terada, Naohiro, Finkel, Richard S, Berg, Jonathan S, Chahin, Nizar, Pacak, Christina A, Wagner, Richard E, Alexander, Matthew S, Draper, Isabelle, Kang, Peter B

    Published in Human molecular genetics (15-07-2019)
    “…Abstract MEGF10 myopathy is a rare inherited muscle disease that is named after the causative gene, MEGF10. The classic phenotype, early onset myopathy,…”
    Get full text
    Journal Article
  4. 4

    Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1 Diabetes by Wallet, Mark A, Santostefano, Katherine E, Terada, Naohiro, Brusko, Todd M

    Published in Frontiers in endocrinology (Lausanne) (18-10-2017)
    “…At least 57 independent loci within the human genome confer varying degrees of risk for the development of type 1 diabetes (T1D). The majority of these…”
    Get full text
    Journal Article
  5. 5

    Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation by Kuang, Yu-Lin, Munoz, Antonio, Nalula, Gilbert, Santostefano, Katherine E., Sanghez, Valentina, Sanchez, Gabriela, Terada, Naohiro, Mattis, Aras N., Iacovino, Michelina, Iribarren, Carlos, Krauss, Ronald M., Medina, Marisa W.

    Published in Stem cell research (01-05-2019)
    “…Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and…”
    Get full text
    Journal Article
  6. 6
  7. 7

    Fibroblast Growth Factor Receptor 2 Homodimerization Rapidly Reduces Transcription of the Pluripotency Gene Nanog without Dissociation of Activating Transcription Factors by Santostefano, Katherine E., Hamazaki, Takashi, Pardo, Carolina E., Kladde, Michael P., Terada, Naohiro

    Published in The Journal of biological chemistry (31-08-2012)
    “…Nanog or Gata6-positive cells co-exist and are convertible within the inner cell mass of murine blastocysts and embryonic stem (ES) cells. Previous studies…”
    Get full text
    Journal Article
  8. 8
  9. 9

    Generation of neural cells from DM1 induced pluripotent stem cells as cellular model for the study of central nervous system neuropathogenesis by Xia, Guangbin, Santostefano, Katherine E, Goodwin, Marianne, Liu, Jilin, Subramony, S H, Swanson, Maurice S, Terada, Naohiro, Ashizawa, Tetsuo

    Published in Cellular reprogramming (01-04-2013)
    “…Dystrophia myotonica type 1 (DM1) is an autosomal dominant multisystem disorder. The pathogenesis of central nervous system (CNS) involvement is poorly…”
    Get more information
    Journal Article
  10. 10

    A pathologist’s perspective on induced pluripotent stem cells by Watanabe, Noriko, Santostefano, Katherine E, Yachnis, Anthony T, Terada, Naohiro

    Published in Laboratory investigation (01-10-2017)
    “…Induced pluripotent stem cell (iPSC) technology was originally developed in 2006. Essentially, it converts somatic cells into pluripotent stem cells by…”
    Get full text
    Journal Article
  11. 11

    A practical guide to induced pluripotent stem cell research using patient samples by Santostefano, Katherine E, Hamazaki, Takashi, Biel, Nikolett M, Jin, Shouguang, Umezawa, Akihiro, Terada, Naohiro

    Published in Laboratory investigation (01-01-2015)
    “…Approximately 3 years ago, we assessed how patient induced pluripotent stem cell (iPSC) research could potentially impact human pathobiology studies in the…”
    Get full text
    Journal Article
  12. 12
  13. 13
  14. 14

    E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b by Leseva, Milena, Santostefano, Katherine E, Rosenbluth, Amy L, Hamazaki, Takashi, Terada, Naohiro

    Published in Epigenetics (01-08-2013)
    “…The E2f6 transcriptional repressor is an E2F-family member essential for the silencing of a group of meiosis-specific genes in somatic tissues. Although E2f6…”
    Get full text
    Journal Article
  15. 15

    Disulfide bond disrupting agents activate the unfolded protein response in EGFR- and HER2-positive breast tumor cells by Ferreira, Renan B, Wang, Mengxiong, Law, Mary E, Davis, Bradley J, Bartley, Ashton N, Higgins, Paul J, Kilberg, Michael S, Santostefano, Katherine E, Terada, Naohiro, Heldermon, Coy D, Castellano, Ronald K, Law, Brian K

    Published in Oncotarget (25-04-2017)
    “…Many breast cancer deaths result from tumors acquiring resistance to available therapies. Thus, new therapeutic agents are needed for targeting drug-resistant…”
    Get full text
    Journal Article
  16. 16

    Efficient Gene Editing in Pluripotent Stem Cells by Bacterial Injection of Transcription Activator‐Like Effector Nuclease Proteins by Jia, Jingyue, Bai, Fang, Jin, Yongxin, Santostefano, Katherine E., Ha, Un-Hwan, Wu, Donghai, Wu, Weihui, Terada, Naohiro, Jin, Shouguang

    Published in Stem cells translational medicine (01-08-2015)
    “…The method of bacterial type III secretion system (T3SS)‐mediated transcription activator‐like effector nuclease (TALEN) protein injection and transfection of…”
    Get full text
    Journal Article
  17. 17
  18. 18