Search Results - "Santoso, Michelle R."

Paracrine Effects of the Pluripotent Stem Cell-Derived Cardiac Myocytes Salvage the Injured Myocardium by Tachibana, Atsushi, Santoso, Michelle R, Mahmoudi, Morteza, Shukla, Praveen, Wang, Lei, Bennett, Mihoko, Goldstone, Andrew B, Wang, Mouer, Fukushi, Masahiro, Ebert, Antje D, Woo, Y Joseph, Rulifson, Eric, Yang, Phillip C

“…RATIONALE:Cardiac myocytes derived from pluripotent stem cells have demonstrated the potential to mitigate damage of the infarcted myocardium and improve left…”
Get full text

Stem Cell-Derived Exosomes Protect Astrocyte Cultures From in vitro Ischemia and Decrease Injury as Post-stroke Intravenous Therapy by Sun, Xiaoyun, Jung, Ji-Hye, Arvola, Oiva, Santoso, Michelle R., Giffard, Rona G., Yang, Phillip C., Stary, Creed M.

“…In the present study we assessed efficacy of exosomes harvested from human and mouse stem cell cultures in protection of mouse primary astrocyte and neuronal…”
Get full text

Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair by Santoso, Michelle R, Ikeda, Gentaro, Tada, Yuko, Jung, Ji-Hye, Vaskova, Evgeniya, Sierra, Raymond G, Gati, Cornelius, Goldstone, Andrew B, von Bornstaedt, Daniel, Shukla, Praveen, Wu, Joseph C, Wakatsuki, Soichi, Woo, Y Joseph, Yang, Phillip C

“…Background Induced pluripotent stem cells and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient-specific therapy for ischemic…”
Get full text

Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction by Santoso, Michelle R., Yang, Phillip C.

“…Stem cell therapy has broad applications in regenerative medicine and increasingly within cardiovascular disease. Stem cells have emerged as a leading…”
Get full text

Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology by Hajipour, Mohammad Javad, Santoso, Michelle R., Rezaee, Farhad, Aghaverdi, Haniyeh, Mahmoudi, Morteza, Perry, George

“…Alzheimer’s disease (AD) is a type of dementia that causes major issues for patients’ memory, thinking, and behavior. Despite efforts to advance AD diagnostic…”
Get full text

Mitochondria-Rich Extracellular Vesicles From Autologous Stem Cell-Derived Cardiomyocytes Restore Energetics of Ischemic Myocardium by Ikeda, Gentaro, Santoso, Michelle R, Tada, Yuko, Li, Albert M, Vaskova, Evgeniya, Jung, Ji-Hye, O'Brien, Connor, Egan, Elizabeth, Ye, Jiangbin, Yang, Phillip C

“…Mitochondrial dysfunction results in an imbalance between energy supply and demand in a failing heart. An innovative therapy that targets the intracellular…”
Get full text

Effect of Cell Sex on Uptake of Nanoparticles: The Overlooked Factor at the Nanobio Interface by Serpooshan, Vahid, Sheibani, Sara, Pushparaj, Pooja, Wojcik, Michal, Jang, Albert Y, Santoso, Michelle R, Jang, Joyce H, Huang, Haina, Safavi-Sohi, Reihaneh, Haghjoo, Niloofar, Nejadnik, Hossein, Aghaverdi, Haniyeh, Vali, Hojatollah, Kinsella, Joseph Matthew, Presley, John, Xu, Ke, Yang, Phillip Chung-Ming, Mahmoudi, Morteza

“…Cellular uptake of nanoparticles (NPs) depends on the nature of the nanobio system including the solid nanocomponents (e.g., physicochemical properties of…”
Get full text

Dual Contrast Manganese-Enhanced MRI and Gadolinium Delayed-Enhanced MRI Detect Heterogenous Myocardial Viability in Ischemic Cardiomyopathy by Tada, Yuko, Santoso, Michelle R., Heidary, Shahriar, Sano, Hiromi, Tachibana, Atsushi, Matsuura, Yuka, Harnish, Phillip, Yang, Phillip C.

Get full text

miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury by Jung, Ji-Hye, Ikeda, Gentaro, Tada, Yuko, von Bornstädt, Daniel, Santoso, Michelle R., Wahlquist, Christine, Rhee, Siyeon, Jeon, Young-Jun, Yu, Anthony C., O’brien, Connor G., Red-Horse, Kristy, Appel, Eric A., Mercola, Mark, Woo, Joseph, Yang, Phillip C.

“…Endogenous capability of the post-mitotic human heart holds great promise to restore the injured myocardium. Recent evidence indicates that the extracellular…”
Get full text

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells) by Perin, Emerson C, Murphy, Michael P, March, Keith L, Bolli, Roberto, Loughran, John, Yang, Phillip C, Leeper, Nicholas J, Dalman, Ronald L, Alexander, Jason, Henry, Timothy D, Traverse, Jay H, Pepine, Carl J, Anderson, R David, Berceli, Scott, Willerson, James T, Muthupillai, Raja, Gahremanpour, Amir, Raveendran, Ganesh, Velasquez, Omaida, Hare, Joshua M, Hernandez Schulman, Ivonne, Kasi, Vijaykumar S, Hiatt, William R, Ambale-Venkatesh, Bharath, Lima, João A, Taylor, Doris A, Resende, Micheline, Gee, Adrian P, Durett, April G, Bloom, Jeanette, Richman, Sara, G'Sell, Patricia, Williams, Shari, Khan, Fouzia, Gyang Ross, Elsie, Santoso, Michelle R, Goldman, JoAnne, Leach, Dana, Handberg, Eileen, Cheong, Benjamin, Piece, Nichole, DiFede, Darcy, Bruhn-Ding, Barb, Caldwell, Emily, Bettencourt, Judy, Lai, Dejian, Piller, Linda, Simpson, Lara, Cohen, Michelle, Sayre, Shelly L, Vojvodic, Rachel W, Moyé, Lem, Ebert, Ray F, Simari, Robert D, Hirsch, Alan T

“…Atherosclerotic peripheral artery disease affects 8% to 12% of Americans >65 years of age and is associated with a major decline in functional status,…”
Get full text

Molecular Imaging of Stem Cells and Exosomes for Myocardial Regeneration by Santoso, Michelle R., Yang, Phillip C.

“…Purpose of Review Stem cell therapy is studied for the treatment of ischemic heart disease. Despite high expectations, investigation has yielded mixed results…”
Get full text

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN Patients with Intermittent Claudication Injected with ALDH Bright Cells (PACE) Trial by Perin, Emerson C, Murphy, Michael P, March, Keith L, Bolli, Roberto, Loughran, John, Yang, Phillip C, Leeper, Nicholas J, Dalman, Ronald L, Alexander, Jason, Henry, Timothy D, Traverse, Jay H, Pepine, Carl J, Anderson, R David, Berceli, Scott, Willerson, James T, Muthupillai, Raja, Gahremanpour, Amir, Raveendran, Ganesh, Velasquez, Omaida, Hare, Joshua M, Schulman, Ivonne Hernandez, Kasi, Vijaykumar S, Hiatt, William R, Ambale-Venkatesh, Bharath, Lima, João A, Taylor, Doris A, Resende, Micheline, Gee, Adrian P, Durett, April G, Bloom, Jeanette, Richman, Sara, GʼSell, Patricia, Williams, Shari, Khan, Fouzia, Ross, Elsie Gyang, Santoso, Michelle R, Goldman, JoAnne, Leach, Dana, Handberg, Eileen, Cheong, Benjamin, Piece, Nichole, DiFede, Darcy, Bruhn-Ding, Barb, Caldwell, Emily, Bettencourt, Judy, Lai, Dejian, Piller, Linda, Simpson, Lara, Cohen, Michelle, Sayre, Shelly L, Vojvodic, Rachel W, Moyé, Lem, Ebert, Ray F, Simari, Robert D, Hirsch, Alan T

“…BACKGROUND—Atherosclerotic peripheral artery disease (PAD) affects 8-12% of Americans over 65 and is associated with a major decline in functional status,…”
Get full text

Abstract 16965: Microvesicles Rescue Cardiomyocytes From Doxorubicin Injury in a Patient Specific Model of Anthracycline Induced Cardiomyopathy by O’Brien, Connor G, Shi, Liye, Santoso, Michelle R, Jung, Ji-Hye, Vaskova, Evgeniya, Ikeda, Gentaro, Ozen, Mehmet O, Demirci, Utkan, Yang, Phillip C

“…IntroductionAnthracyclines are highly effective chemotherapeutic agents associated with cardiac toxicity. Anthracycline induced cardiomyopathy (AIC) carries a…”
Get full text

Abstract 17203: Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Salvage the Injured Myocardium by Modulation of Autophagy by Santoso, Michelle R, Tada, Yuko, Ikeda, Gentaro, Jung, Ji-Hye, Vaskova, Evgeniya, Sierra, Raymond G, Gati, Cornelius, Goldstone, Andrew B, Bornstaedt, Daniel V, Shukla, Praveen, Wu, Joseph C, Wakatsuki, Soichi, Woo, Joseph, Yang, Phillip C

“…BackgroundInduced pluripotent stem cells (iPSCs) and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient-specific therapy for…”
Get full text

Abstract 14375: Mitochondria-Containing Extracellular Vesicles Restore Intracellular ATP Production and Promote Viability in Injured Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Ikeda, Gentaro, Santoso, Michelle R, Tada, Yuko, Vaskova, Evgeniya, Jung, Ji-Hye, Galen, Connor O, Shi, Liye, Yang, Phillip

“…IntroductionMitochondrial dysfunction disrupts the balance between energy supply and demand in the failing heart. A novel therapy that promotes cellular…”
Get full text