Search Results - "Santosh Mishra"

The Cells and Circuitry for Itch Responses in Mice by Mishra, Santosh K., Hoon, Mark A.

“…Itch is triggered by somatosensory neurons expressing the ion channel TRPV1 (transient receptor potential cation channel subfamily V member 1), but the…”
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The Role of CNTNAP2 in Itch Sensation by Mishra, Santosh K.

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Role of TRP ion channels in pruritus by Shirolkar, Parth, Mishra, Santosh K.

“…•Discuss the role of TRP channels in the skin involved in itch.•Discuss the role of TRP channels in the sensory neurons that detect and transmit…”
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The emerging role of neuroimmune interactions in atopic dermatitis and itch by Fan, Jennifer, Mishra, Santosh K.

“…Millions of people globally suffer from allergic diseases, and the cases have been rising in the past decades. One of the major manifestations of allergic…”
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Periostin, an Emerging Player in Itch Sensation by Hashimoto, Takashi, Mishra, Santosh K., Olivry, Thierry, Yosipovitch, Gil

“…Periostin, an extracellular matrix and matricellular protein, binds to several types of integrins that transduce its signals. Its function in allergic…”
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A new role of TRPM8 in circadian rhythm and molecular clock by Mishra, Santosh K., Gaddameedhi, Shobhan

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The cellular code for mammalian thermosensation by Pogorzala, Leah A, Mishra, Santosh K, Hoon, Mark A

“…Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably discriminate hot from cold and to select their preferred environments…”
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Circuit dissection of the role of somatostatin in itch and pain by Huang, Jing, Polgár, Erika, Solinski, Hans Jürgen, Mishra, Santosh K., Tseng, Pang-Yen, Iwagaki, Noboru, Boyle, Kieran A., Dickie, Allen C., Kriegbaum, Mette C., Wildner, Hendrik, Zeilhofer, Hanns Ulrich, Watanabe, Masahiko, Riddell, John S., Todd, Andrew J., Hoon, Mark A.

“…Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which…”
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Emerging evidence of artemin/GFRα3 signaling in musculoskeletal pain by Gupta, Ankita, Mishra, Santosh K., Lascelles, B. Duncan X.

“…Chronic musculoskeletal pain is highly prevalent and poses a significant personal, societal, and economic burden. Management of chronic musculoskeletal pain…”
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De novo SVM classification of precursor microRNAs from genomic pseudo hairpins using global and intrinsic folding measures by Ng, Kwang Loong Stanley, Mishra, Santosh K.

“…Motivation: MicroRNAs (miRNAs) are small ncRNAs participating in diverse cellular and physiological processes through the post-transcriptional gene regulatory…”
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TRPV1-lineage neurons are required for thermal sensation by Mishra, Santosh K, Tisel, Sarah M, Orestes, Peihan, Bhangoo, Sonia K, Hoon, Mark A

“…The ion‐channel TRPV1 is believed to be a major sensor of noxious heat, but surprisingly animals lacking TRPV1 still display marked responses to elevated…”
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Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch by Mishra, Santosh K., Wheeler, Joshua J., Pitake, Saumitra, Ding, Huiping, Jiang, Changyu, Fukuyama, Tomoki, Paps, Judy S., Ralph, Patrick, Coyne, Jacob, Parkington, Michelle, DeBrecht, Jennifer, Ehrhardt-Humbert, Lauren C., Cruse, Glenn P., Bäumer, Wolfgang, Ji, Ru-Rong, Ko, Mei-Chuan, Olivry, Thierry

“…Chronic allergic itch is a common symptom affecting millions of people and animals, but its pathogenesis is not fully explained. Herein, we show that…”
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Oxidation of Sulfonamide Antimicrobials by Ferrate(VI) [FeVIO4 2-] by Sharma, Virender K, Mishra, Santosh K, Nesnas, Nasri

“…Sulfonamide antimicrobials are used in both human therapy and animal husbandry. Sulfonamides are not readily biodegradable and have been detected in surface…”
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Inflammation Induced Sensory Nerve Growth and Pain Hypersensitivity Requires the N-Type Calcium Channel Cav2.2 by Pitake, Saumitra, Middleton, Leah J., Abdus-Saboor, Ishmail, Mishra, Santosh K.

“…Voltage-gated calcium channels (VGCCs) are important mediators of pain hypersensitivity during inflammatory states, but their role in sensory nerve growth…”
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Janus kinase inhibitors display broad anti-itch properties: A possible link through the TRPV1 receptor by Fukuyama, Tomoki, Ganchingco, Joy Rachel, Mishra, Santosh K, Olivry, Thierry, Rzagalinski, Ignacy, Volmer, Dietrich A, Bäumer, Wolfgang

“…[...]TDI-challenged mice topically treated with tofacitinib during the challenge phase showed a significant decrease in itch behavior (Fig 2, E). [...]we…”
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TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch by Wilzopolski, Jenny, Kietzmann, Manfred, Mishra, Santosh K, Stark, Holger, Bäumer, Wolfgang, Rossbach, Kristine

“…Two histamine receptor subtypes (HR), namely H1R and H4R, are involved in the transmission of histamine-induced itch as key components. Although exact…”
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Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation by Mishra, Santosh K., Hoon, Mark A.

“…Here we make use of neural ablation to investigate the properties of the TrpV1-expressing neurons in the trigeminal and dorsal root ganglia of mice…”
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Differential contribution of sensory transient receptor potential channels in response to the bioactive lipid sphingosine-1-phosphate by Kittaka, Hiroki, DeBrecht, Jennifer, Mishra, Santosh K

“…Somatosensation encompasses a wide range of sensations including pain, itch, touch, and temperature and is essential for the detection of environmental…”
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A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice by Shukla, Varsha, Zheng, Ya‐Li, Mishra, Santosh K., Amin, Niranjana D., Steiner, Joseph, Grant, Philip, Kesavapany, Sashi, Pant, Harish C.

“…Alzheimer's disease (AD), one of the leading neurodegenerative disorders of older adults, which causes major socioeconomic burdens globally, lacks effective…”
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Glucoconjugated Dinuclear Copper(II) Complex: An Efficient Catalyst for Stereoselective Synthesis of Trisubstituted Propargylamines via Solvent-free A3 Coupling Reaction by Mishra, Santosh Kumar, Parikh, Parmeshthi, Parikh, Anuvasita, Rangan, Krishnan, Sah, Ajay K

“…Development of catalytic systems using nontoxic natural precursors is the need of the era, and along this line, we have synthesized a new D-glucose derived…”
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