Search Results - "Santos Cruz, Jader"

Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents by de Sousa, Damião Pergentino, Gonçalves, Juan Carlos Ramos, Quintans-Júnior, Lucindo, Cruz, Jader Santos, Araújo, Demétrius Antonio Machado, de Almeida, Reinaldo Nóbrega

“…Citronellol is one monoterpene alcohol, which is present in the essential oils of various aromatic plant species. This study evaluated the neuroprotective…”
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Linalool blocks excitability in peripheral nerves and voltage-dependent Na + current in dissociated dorsal root ganglia neurons by Leal-Cardoso, José Henrique, da Silva-Alves, Kerly Shamyra, Ferreira-da-Silva, Francisco Walber, dos Santos-Nascimento, Tiago, Joca, Humberto Cavalcante, de Macedo, Flávio Henrique Pequeno, de Albuquerque-Neto, Pedro Militão, Magalhães, Pedro Jorge Caldas, Lahlou, Saad, Cruz, Jader Santos, Barbosa, Roseli

“…Linalool is a terpene that occurs as a major constituent of essential oils of many plants of widespread distribution. It possesses several biological and…”
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trans-Caryophyllene, a natural sesquiterpene, causes tracheal smooth muscle relaxation through blockade of voltage-dependent Ca²⁺ channels by Pinho-da-Silva, Leidiane, Mendes-Maia, Paula Virgínia, Teófilo, Taylena Maria do Nascimento Garcia, Barbosa, Roseli, Ceccatto, Vania Marilande, Coelho-de-Souza, Andrelina Noronha, Santos Cruz, Jader, Leal-Cardoso, José Henrique

“…trans-Caryophyllene is a major component in the essential oils of various species of medicinal plants used in popular medicine in Brazil. It belongs to the…”
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R(+)-pulegone impairs Ca²⁺ homeostasis and causes negative inotropism in mammalian myocardium by de Cerqueira, Sandra Valeria Santos, Gondim, Antonio Nei Santana, Roman-Campos, Danilo, Cruz, Jader Santos, Passos, Amilton Gustavo da Silva, Lauton-Santos, Sandra, Lara, Aline, Guatimosim, Silvia, Conde-Garcia, Eduardo Antonio, de Oliveira, Evaleide Diniz, de Vasconcelos, Carla Maria Lins

“…The present study aimed to investigate the inotropic effects of R(+)-pulegone, a monoterpene found in plant species belonging to the genus Mentha, on the…”
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Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release by Sobie, Eric A, Dilly, Keith W, dos Santos Cruz, Jader, Lederer, W Jonathan, Jafri, M Saleet

“…A Ca(2+) spark arises when a cluster of sarcoplasmic reticulum (SR) channels (ryanodine receptors or RyRs) opens to release calcium in a locally regenerative…”
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TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation by Silva, Darizy Flavia, de Almeida, Monica Moura, Chaves, Cinthia Guedes, Braz, Ana Letícia, Gomes, Maria Aparecida, Pinho-da-Silva, Leidiane, Pesquero, Jorge Luiz, Andrade, Viviane Aguiar, Leite, Maria de Fátima, de Albuquerque, José George Ferreira, Araujo, Islania Giselia Albuquerque, Nunes, Xirley Pereira, Barbosa-Filho, José Maria, Cruz, Jader dos Santos, Correia, Nadja de Azevedo, de Medeiros, Isac Almeida

“…In this study, our aims were to investigate transient receptor potential melastatin-8 channels (TRPM8) involvement in rotundifolone induced relaxation in the…”
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Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease by Santos-Miranda, Artur, Joviano-Santos, Julliane Vasconcelos, Ribeiro, Grazielle Alves, Botelho, Ana Flávia M, Rocha, Peter, Vieira, Leda Quercia, Cruz, Jader Santos, Roman-Campos, Danilo

“…Chagas Disease (CD) is one of the leading causes of heart failure and sudden death in Latin America. Treatments with antioxidants have provided promising…”
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Current aspects of thiamine deficiency on heart function by Roman-Campos, Danilo, Cruz, Jader Santos

“…Beriberi is a disease caused by thiamine deficiency (TD), which may lead to heart problems, including heart failure. Despite the fact that thiamine prevalence…”
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Calcium overload-induced arrhythmia is suppressed by farnesol in rat heart by Souza, Diego Santos de, Menezes-Filho, José Evaldo Rodrigues de, Santos-Miranda, Artur, Jesus, Itamar Couto Guedes de, Silva Neto, Júlio Alves, Guatimosim, Silvia, Cruz, Jader Santos, Vasconcelos, Carla Maria Lins de

“…Cardiac arrhythmias are among the most important pathologies that lead to sudden death. The discovery of new therapeutic options against arrhythmias with low…”
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Proteomic analysis reveals stage‐specific reprogramed metabolism for the primary breast cancer cell lines MGSO‐3 and MACL‐1 by Braga, Fabio Henrique Guimarães, Gómez‐Mendoza, Diana Paola, Lemos, Rafael Pereira, Rodrigues‐Ribeiro, Lucas, Raíssa‐Oliveira, Brenda, Rodrigues, Andréia Laura Prates, Gorshkov, Vladimir, Kjeldsen, Frank, Cruz, Jader Santos, Verano‐Braga, Thiago

“…Breast cancer is the most prevalent cancer in women worldwide. Its molecular subtypes are based on the presence/absence of estrogen receptor (ER), progesterone…”
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Correction: Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease by Santos-Miranda, Artur, Joviano-Santos, Julliane Vasconcelos, Ribeiro, Grazielle Alves, Botelho, Ana Flávia M, Rocha, Peter, Vieira, Leda Quercia, Cruz, Jader Santos, Roman-Campos, Danilo

“…[This corrects the article DOI: 10.1371/journal.ppat.1008379.]…”
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Molecular mechanisms of cardiac electromechanical remodeling during Chagas disease: Role of TNF and TGF-β by Cruz, Jader Santos, PhD, Machado, Fabiana Simão, PhD, Ropert, Catherine, PhD, Roman-Campos, Danilo, PhD

“…Abstract Chagas disease is caused by the trypanosomatid Trypanosoma cruzi , which chronically causes heart problems in up to 30% of infected patients. Chagas…”
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Essential oils components as a new path to understand ion channel molecular pharmacology by de Araújo, Demetrius Antonio Machado, Freitas, Christiane, Cruz, Jader Santos

“…The discovery and development of new drugs targeting voltage-gated ion channels are important for treating a variety of medical conditions and diseases. Ion…”
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Carvacrol modulates voltage-gated sodium channels kinetics in dorsal root ganglia by Joca, Humberto Cavalcante, Vieira, Daiana Cardoso Oliveira, Vasconcelos, Aliny Perreira, Araújo, Demetrius Antônio Machado, Cruz, Jader Santos

“…Recent studies have shown that many of plant-derived compounds interact with specific ion channels and thereby modulate many sensing mechanisms, such as…”
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Inhibitory Effect of Terpinen-4-ol on Voltage-Dependent Potassium Currents in Rat Small Sensory Neurons by Santos-Nascimento, Tiago dos, Veras, Kleyane Morais, Cruz, Jader Santos, Leal-Cardoso, José Henrique

“…The biological and pharmacological activities of the terpenoid terpinen-4-ol (1), which include depressant effects in the central nervous system, are of…”
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Role of SOCS2 in Modulating Heart Damage and Function in a Murine Model of Acute Chagas Disease by Esper, Lisia, Roman-Campos, Danilo, Lara, Aline, Brant, Fatima, Castro, Luisa L, Barroso, Andreia, Araujo, Ronan Ricardo S, Vieira, Leda Q, Mukherjee, Shankar, Gomes, Eneas Ricardo M, Rocha, Nazareth N, Ramos, Isalira P.R, Lisanti, Michael P, Campos, Camila F, Arantes, Rosa M.E, Guatimosim, Silvia, Weiss, Louis M, Cruz, Jader Santos, Tanowitz, Herbert B, Teixeira, Mauro M, Machado, Fabiana S

“…Infection with Trypanosoma cruzi induces inflammation, which limits parasite proliferation but may result in chagasic heart disease. Suppressor of cytokine…”
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Larvicide Activity on Aedes aegypti of Essential Oil Nanoemulsion from the Protium heptaphyllum Resin by Faustino, Cleidjane Gomes, de Medeiros, Fernando Antônio, Ribeiro Galardo, Allan Kardec, Lobato Rodrigues, Alex Bruno, Lopes Martins, Rosany, de Medeiros Souza Lima, Yuri, Fechine Tavares, Josean, Alves de Medeiros, Marcos Antônio, Dos Santos Cruz, Jader, Almeida, Sheylla Susan Moreira da Silva de

“…The aim of this work was to prepare a nanoemulsion containing the essential oil of resin and to evaluate the larvicidal activity and the residual larvicidal…”
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Geraniol Blocks Calcium and Potassium Channels in the Mammalian Myocardium: Useful Effects to Treat Arrhythmias by Menezes‐Filho, José Evaldo Rodrigues, Gondim, Antônio Nei Santana, Cruz, Jader Santos, Souza, Américo Azevedo, Santos, José Nilson Andrade dos, Conde‐Garcia, Eduardo Antônio, Sousa, Damião Pergentino, Santos, Michel Santana, Oliveira, Evaleide Diniz, Vasconcelos, Carla Maria Lins

“…Geraniol is a monoterpene present in several essential oils, and it is known to have a plethora of pharmacological activities. In this study, we explored the…”
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d‑Limonene Ameliorates Myocardial Infarction Injury by Reducing Reactive Oxygen Species and Cell Apoptosis in a Murine Model by Durço, Aimée Obolari, de Souza, Diego Santos, Heimfarth, Luana, Miguel-dos-Santos, Rodrigo, Rabelo, Thallita Kelly, Oliveira Barreto, Tatiane de, Rhana, Paula, Santos Santana, Michael Nadson, Braga, Weslley Fernandes, Santos Cruz, Jader dos, Lauton-Santos, Sandra, Santana-Filho, Valter Joviniano de, Barreto, Rosana de Souza Siqueira, Guimarães, Adriana Gibara, Alvarez-Leite, Jacqueline Isaura, Quintans Júnior, Lucindo José, Vasconcelos, Carla Maria Lins de, Santos, Márcio Roberto Viana dos, Barreto, André Sales

“…Myocardial infarction (MI) leads to high mortality, and pharmacological or percutaneous primary interventions do not significantly inhibit ischemia/reperfusion…”
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Regional effects of low-intensity endurance training on structural and mechanical properties of rat ventricular myocytes by Carneiro-Júnior, Miguel Araujo, Prímola-Gomes, Thales Nicolau, Quintão-Júnior, Judson Fonseca, Drummond, Lucas Rios, Lavorato, Victor Neiva, Drummond, Filipe Rios, Felix, Leonardo Bonato, Oliveira, Edilamar Menezes, Cruz, Jader Santos, Natali, Antonio José, Mill, José Geraldo

“…We tested the effects of low-intensity endurance training (LIET) on the structural and mechanical properties of right (RV) and left ventricular (LV) myocytes…”
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