Search Results - "Santos‐Laso, Álvaro"

miR-21-5p promotes NASH-related hepatocarcinogenesis by Rodrigues, Pedro M, Afonso, Marta B, Simão, André L, Islam, Tawhidul, Gaspar, Maria M, O'Rourke, Colm J, Lewinska, Monika, Andersen, Jesper B, Arretxe, Enara, Alonso, Cristina, Santos-Laso, Álvaro, Izquierdo-Sanchez, Laura, Jimenez-Agüero, Raúl, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria J, Prip-Buus, Carina, Banales, Jesus M, Rodrigues, Cecília M P, Castro, Rui E

“…The mechanisms governing the progression of non-alcoholic fatty liver disease (NAFLD) towards steatohepatitis (NASH) and hepatocellular carcinoma (HCC) remain…”
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Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma by Arbelaiz, Ander, Azkargorta, Mikel, Krawczyk, Marcin, Santos‐Laso, Alvaro, Lapitz, Ainhoa, Perugorria, Maria J., Erice, Oihane, Gonzalez, Esperanza, Jimenez‐Agüero, Raul, Lacasta, Adelaida, Ibarra, Cesar, Sanchez‐Campos, Alberto, Jimeno, Juan P., Lammert, Frank, Milkiewicz, Piotr, Marzioni, Marco, Macias, Rocio I.R., Marin, Jose J.G., Patel, Tushar, Gores, Gregory J., Martinez, Ibon, Elortza, Félix, Falcon‐Perez, Juan M., Bujanda, Luis, Banales, Jesus M.

“…Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with poor prognosis. Several conditions, such as primary sclerosing cholangitis…”
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Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis by Banales, Jesus M., Iñarrairaegui, Mercedes, Arbelaiz, Ander, Milkiewicz, Piotr, Muntané, Jordi, Muñoz‐Bellvis, Luis, La Casta, Adelaida, Gonzalez, Luis M., Arretxe, Enara, Alonso, Cristina, Martínez‐Arranz, Ibon, Lapitz, Ainhoa, Santos‐Laso, Alvaro, Avila, Matias A., Martínez‐Chantar, Maria L., Bujanda, Luis, Marin, Jose J.G., Sangro, Bruno, Macias, Rocio I.R.

“…Early and differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC) by noninvasive methods represents a current…”
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Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System by Lamarca, Angela, Santos‐Laso, Alvaro, Utpatel, Kirsten, La Casta, Adelaida, Stock, Simone, Forner, Alejandro, Adeva, Jorge, Folseraas, Trine, Fabris, Luca, Macias, Rocio I.R., Krawczyk, Marcin, Krawczyk, Marek, Cardinale, Vincenzo, Braconi, Chiara, Alvaro, Domenico, Evert, Matthias, Banales, Jesus M., Valle, Juan W.

“…Background and Aims Intrahepatic cholangiocarcinoma (iCCA) with liver metastases is perceived to have a poor prognosis, but the American Joint Committee on…”
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MicroRNA‐506 promotes primary biliary cholangitis–like features in cholangiocytes and immune activation by Erice, Oihane, Munoz‐Garrido, Patricia, Vaquero, Javier, Perugorria, Maria J., Fernandez‐Barrena, Maite G., Saez, Elena, Santos‐Laso, Alvaro, Arbelaiz, Ander, Jimenez‐Agüero, Raul, Fernandez‐Irigoyen, Joaquin, Santamaria, Enrique, Torrano, Verónica, Carracedo, Arkaitz, Ananthanarayanan, Meenakshisundaram, Marzioni, Marco, Prieto, Jesus, Beuers, Ulrich, Oude Elferink, Ronald P., LaRusso, Nicholas F., Bujanda, Luis, Marin, Jose J.G., Banales, Jesus M.

“…Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease associated with autoimmune phenomena targeting intrahepatic bile duct cells…”
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Faecal Microbiota Transplantation, Paving the Way to Treat Non-Alcoholic Fatty Liver Disease by Del Barrio, María, Lavín, Lucía, Santos-Laso, Álvaro, Arias-Loste, Maria Teresa, Odriozola, Aitor, Rodriguez-Duque, Juan Carlos, Rivas, Coral, Iruzubieta, Paula, Crespo, Javier

“…Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent cause of chronic liver disease (CLD). Currently, the only therapeutic recommendation…”
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Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma by Colyn, Leticia, Bárcena‐Varela, Marina, Álvarez‐Sola, Gloria, Latasa, M. Ujue, Uriarte, Iker, Santamaría, Eva, Herranz, Jose M., Santos‐Laso, Alvaro, Arechederra, Maria, Ruiz de Gauna, Mikel, Aspichueta, Patricia, Canale, Matteo, Casadei‐Gardini, Andrea, Francesconi, Maria, Carotti, Simone, Morini, Sergio, Nelson, Leonard J., Iraburu, Maria J., Chen, Chaobo, Sangro, Bruno, Marin, Jose J.G., Martinez‐Chantar, Maria L., Banales, Jesus M., Arnes‐Benito, Robert, Huch, Meritxell, Patino, John M., Dar, Altaf A., Nosrati, Mehdi, Oyarzábal, Julen, Prósper, Felipe, Urman, Jesus, Cubero, Francisco Javier, Trautwein, Christian, Berasain, Carmen, Fernandez‐Barrena, Maite G., Avila, Matias A.

“…Background and Aims Cholangiocarcinoma (CCA) is a devastating disease often detected at advanced stages when surgery cannot be performed. Conventional and…”
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Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets by Santos‐Laso, Alvaro, Izquierdo‐Sanchez, Laura, Rodrigues, Pedro M., Huang, Bing Q., Azkargorta, Mikel, Lapitz, Ainhoa, Munoz‐Garrido, Patricia, Arbelaiz, Ander, Caballero-Camino, Francisco J., Fernández‐Barrena, Maite G., Jimenez‐Agüero, Raul, Argemi, Josepmaria, Aragon, Tomas, Elortza, Felix, Marzioni, Marco, Drenth, Joost P. H., LaRusso, Nicholas F., Bujanda, Luis, Perugorria, Maria J., Banales, Jesus M., Andersson, Emma

“…Background & Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of multiple biliary cysts. Recently, novel…”
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Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage by Perugorria, Maria J, Esparza-Baquer, Aitor, Oakley, Fiona, Labiano, Ibone, Korosec, Ana, Jais, Alexander, Mann, Jelena, Tiniakos, Dina, Santos-Laso, Alvaro, Arbelaiz, Ander, Gawish, Riem, Sampedro, Ana, Fontanellas, Antonio, Hijona, Elizabeth, Jimenez-Agüero, Raul, Esterbauer, Harald, Stoiber, Dagmar, Bujanda, Luis, Banales, Jesus María, Knapp, Sylvia, Sharif, Omar, Mann, Derek A

“…Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates…”
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Primary biliary cholangitis: A tale of epigenetically-induced secretory failure? by Rodrigues, Pedro M., Perugorria, Maria J., Santos-Laso, Alvaro, Bujanda, Luis, Beuers, Ulrich, Banales, Jesus M.

“…Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease associated with autoimmune-related destruction of small to medium size intrahepatic…”
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RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease by Afonso, Marta B, Rodrigues, Pedro M, Mateus-Pinheiro, Miguel, Simão, André L, Gaspar, Maria M, Majdi, Amine, Arretxe, Enara, Alonso, Cristina, Santos-Laso, Alvaro, Jimenez-Agüero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria Jesus, Banales, Jesus M, Ratziu, Vlad, Gautheron, Jeremie, Castro, Rui E, Rodrigues, Cecília M P

“…Receptor-interacting protein kinase 3 (RIPK3) is a key player in necroptosis execution and an emerging metabolic regulator, whose contribution to non-alcoholic…”
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Dual Targeting of Histone Methyltransferase G9a and DNA‐Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma by Bárcena‐Varela, Marina, Caruso, Stefano, Llerena, Susana, Álvarez‐Sola, Gloria, Uriarte, Iker, Latasa, M. Ujue, Urtasun, Raquel, Rebouissou, Sandra, Alvarez, Laura, Jimenez, Maddalen, Santamaría, Eva, Rodriguez‐Ortigosa, Carlos, Mazza, Giuseppe, Rombouts, Krista, San José‐Eneriz, Edurne, Rabal, Obdulia, Agirre, Xabier, Iraburu, Maria, Santos‐Laso, Alvaro, Banales, Jesus M., Zucman‐Rossi, Jessica, Prósper, Felipe, Oyarzabal, Julen, Berasain, Carmen, Ávila, Matías A., Fernández‐Barrena, Maite G.

“…Epigenetic modifications such as DNA and histone methylation functionally cooperate in fostering tumor growth, including that of hepatocellular carcinoma…”
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SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma by Merino-Azpitarte, Maite, Lozano, Elisa, Perugorria, María J, Esparza-Baquer, Aitor, Erice, Oihane, Santos-Laso, Álvaro, O'Rourke, Colm J, Andersen, Jesper B, Jiménez-Agüero, Raúl, Lacasta, Adelaida, D'Amato, Mauro, Briz, Óscar, Jalan-Sakrikar, Nidhi, Huebert, Robert C, Thelen, Kristen M, Gradilone, Sergio A, Aransay, Ana M, Lavín, José L, Fernández-Barrena, Maite G, Matheu, Ander, Marzioni, Marco, Gores, Gregory J, Bujanda, Luis, Marin, José J.G, Banales, Jesús M

“…Graphical abstract…”
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Fatty Liver Disease, Metabolism and Alcohol Interplay: A Comprehensive Review by Odriozola, Aitor, Santos-Laso, Alvaro, Del Barrio, María, Cabezas, Joaquín, Iruzubieta, Paula, Arias-Loste, María Teresa, Rivas, Coral, Duque, Juan Carlos Rodríguez, Antón, Ángela, Fábrega, Emilio, Crespo, Javier

“…Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, and its incidence has been increasing in recent years…”
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Innovative Therapeutic Approaches in Non-Alcoholic Fatty Liver Disease: When Knowing Your Patient Is Key by Alonso-Peña, Marta, Del Barrio, Maria, Peleteiro-Vigil, Ana, Jimenez-Gonzalez, Carolina, Santos-Laso, Alvaro, Arias-Loste, Maria Teresa, Iruzubieta, Paula, Crespo, Javier

“…Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of disorders ranging from simple steatosis to non-alcoholic steatohepatitis (NASH). Hepatic…”
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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease by Caballero‐Camino, Francisco J., Rivilla, Ivan, Herraez, Elisa, Briz, Oscar, Santos‐Laso, Alvaro, Izquierdo‐Sanchez, Laura, Lee‐Law, Pui Y., Rodrigues, Pedro M., Munoz‐Garrido, Patricia, Jin, Sujeong, Peixoto, Estanislao, Richard, Seth, Gradilone, Sergio A., Perugorria, Maria J., Esteller, Manel, Bujanda, Luis, Marin, Jose J.G., Banales, Jesus M., Cossío, Fernando P.

“…Background and Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current…”
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Feasibility of large-scale population testing for SARS-CoV-2 detection by self-testing at home by Iruzubieta, Paula, Fernández-Lanas, Tatiana, Rasines, Laura, Cayon, Lorena, Álvarez-Cancelo, Ana, Santos-Laso, Alvaro, García-Blanco, Agustín, Curiel-Olmo, Soraya, Cabezas, Joaquín, Wallmann, Reinhard, Fábrega, Emilio, Martínez-Taboada, Víctor M., Hernández, José L., López-Hoyos, Marcos, Lazarus, Jeffrey V., Crespo, Javier

“…The simplicity and low cost of rapid point-of-care tests greatly facilitate large-scale population testing, which can contribute to controlling the spread of…”
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Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease by Munoz-Garrido, Patricia, Marin, José J.G, Perugorria, María J, Urribarri, Aura D, Erice, Oihane, Sáez, Elena, Úriz, Miriam, Sarvide, Sarai, Portu, Ainhoa, Concepcion, Axel R, Romero, Marta R, Monte, María J, Santos-Laso, Álvaro, Hijona, Elizabeth, Jimenez-Agüero, Raúl, Marzioni, Marco, Beuers, Ulrich, Masyuk, Tatyana V, LaRusso, Nicholas F, Prieto, Jesús, Bujanda, Luis, Drenth, Joost P.H, Banales, Jesús M

“…Background & Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive biliary cystogenesis. Current therapies show short-term…”
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Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis by Lapitz, Ainhoa, Arbelaiz, Ander, O'Rourke, Colm J, Lavin, Jose L, Casta, Adelaida La, Ibarra, Cesar, Jimeno, Juan P, Santos-Laso, Alvaro, Izquierdo-Sanchez, Laura, Krawczyk, Marcin, Perugorria, Maria J, Jimenez-Aguero, Raul, Sanchez-Campos, Alberto, Riaño, Ioana, Gónzalez, Esperanza, Lammert, Frank, Marzioni, Marco, Macias, Rocio I R, Marin, Jose J G, Karlsen, Tom H, Bujanda, Luis, Falcón-Pérez, Juan M, Andersen, Jesper B, Aransay, Ana M, Rodrigues, Pedro M, Banales, Jesus M

“…Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary…”
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Adiponectin, Leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD by da Silva Matos Serras Marques, Vanda Isabel, Bento Afonso, Marta, Bierig, Nina, Duarte-Ramos, Filipa, Santos-Laso, Álvaro, Jimenez-Agüero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria J., Luís, Rita, Costa, Adília, Machado, Mariana, Alonso, Cristina, Arretxe, Enara, Alustiza, José M., Krawczyk, Marcin, Lammert, Frank, Tiniakos, Dina G., Flehmig, Bertram, Cortez-Pinto, Helena, Banales, Jesus M., Castro, Rui, Normann, Andrea, Rodrigues, Cecilia

“…Copyright © 2021 Marques, Afonso, Bierig, Duarte-Ramos, Santos-Laso, Jimenez-Agüero, Eizaguirre, Bujanda, Pareja, Luís, Costa, Machado, Alonso, Arretxe,…”
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