Search Results - "Santos‐Falcón, Nieves"

Molecular epidemiology of spinocerebellar ataxias in Cuba: Insights into SCA2 founder effect in Holguin by Velázquez Pérez, Luis, Cruz, Gilberto Sánchez, Santos Falcón, Nieves, Enrique Almaguer Mederos, Luis, Escalona Batallan, Karel, Rodríguez Labrada, Roberto, Paneque Herrera, Milena, Laffita Mesa, José Miguel, Rodríguez Díaz, Julio C., Rodríguez, Raúl Aguilera, González Zaldivar, Yanetza, Coello Almarales, Dany, Almaguer Gotay, Dennis, Jorge Cedeño, Humberto

“…The objective of this study was to determine the prevalence of hereditary ataxias in Cuba, with a special focus on the clinical and molecular features of SCA2…”
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The intricate cellular ecosystem of human peripheral veins as revealed by single-cell transcriptomic analysis by Rojas, Miguel G, Zigmond, Zachary M, Pereira-Simon, Simone, Santos Falcon, Nieves, Suresh Kumar, Maya, Stoyell-Conti, Filipe F, Kosanovic, Christina, Griswold, Anthony J, Salama, Alghidak, Yang, Xiaofeng, Tabbara, Marwan, Vazquez-Padron, Roberto I, Martinez, Laisel

“…The venous system has been historically understudied despite its critical roles in blood distribution, heart function, and systemic immunity. This study…”
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Normal ATXN2 alleles influences on the age at onset in spinocerebellar ataxia type 2 by Almaguer‐Mederos, Luis E., Aguilera‐Rodríguez, Raúl, Cuello‐Almarales, Dany, Almaguer‐Gotay, Dennis, González‐Zaldívar, Yanetza, Vázquez‐Mojena, Yaimé, Santos‐Falcón, Nieves, Sánchez‐Cruz, Gilberto, Velázquez‐Pérez, Luis

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Saccade velocity is controlled by polyglutamine size in spinocerebellar ataxia 2 by Velázquez-Pérez, Luis, Seifried, Carola, Santos-Falcón, Nieves, Abele, Michael, Ziemann, Ulf, Almaguer, Luis Enrique, Martínez-Góngora, Edilberto, Sánchez-Cruz, Gilberto, Canales, Nalia, Pérez-González, Ruth, Velázquez-Manresa, Mercedes, Viebahn, Bettina, Von Stuckrad-Barre, Sebastian, Fetter, Michael, Klockgether, Thomas, Auburger, Georg

“…We assessed maximal saccade velocity (MSV) in 82 spinocerebellar ataxia type 2 (SCA2) patients and 80 controls, correlating it to disease duration,…”
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Gene inactivation of lysyl oxidase in smooth muscle cells reduces atherosclerosis burden and plaque calcification in hyperlipidemic mice by Stoyell-Conti, Filipe F., Suresh Kumar, Maya, Zigmond, Zachary M., Rojas, Miguel G., Santos Falcon, Nieves, Martinez, Laisel, Vazquez-Padron, Roberto I.

“…Lysyl oxidase (LOX) catalyzes the crosslinking of collagen and elastin to maintain tensile strength and structural integrity of the vasculature. Excessive LOX…”
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A Genetic Model of Constitutively Active Integrin CD11b/CD18 by Martinez, Laisel, Li, Xiaobo, Ramos-Echazabal, Gioser, Faridi, Hafeez, Zigmond, Zachary M, Santos Falcon, Nieves, Hernandez, Diana R, Shehadeh, Serene A, Velazquez, Omaida C, Gupta, Vineet, Vazquez-Padron, Roberto I

“…Pharmacological activation of integrin CD11b/CD18 (α β , Mac-1, and CR3) shows anti-inflammatory benefits in a variety of animal models of human disease, and…”
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Active trafficking of alpha 1 antitrypsin across the lung endothelium by Lockett, Angelia D, Brown, Mary Beth, Santos-Falcon, Nieves, Rush, Natalia I, Oueini, Houssam, Oberle, Amber J, Bolanis, Esther, Fragoso, Miryam A, Petrusca, Daniela N, Serban, Karina A, Schweitzer, Kelly S, Presson, Jr, Robert G, Campos, Michael, Petrache, Irina

“…The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung…”
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The Transcriptomics of the Human Vein Transformation After Arteriovenous Fistula Anastomosis Uncovers Layer-Specific Remodeling and Hallmarks of Maturation Failure by Martinez, Laisel, Rojas, Miguel G., Tabbara, Marwan, Pereira-Simon, Simone, Santos Falcon, Nieves, Rauf, Mohd Ahmar, Challa, Akshara, Zigmond, Zachary M., Griswold, Anthony J., Duque, Juan C., Lassance-Soares, Roberta M., Velazquez, Omaida C., Salman, Loay H., Vazquez-Padron, Roberto I.

“…The molecular transformation of the human preaccess vein after arteriovenous fistula (AVF) creation is poorly understood. This limits our ability to design…”
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Single-Cell Analyses Offer Insights into the Different Remodeling Programs of Arteries and Veins by Rojas, Miguel G, Pereira-Simon, Simone, Zigmond, Zachary M, Varona Santos, Javier, Perla, Mikael, Santos Falcon, Nieves, Stoyell-Conti, Filipe F, Salama, Alghidak, Yang, Xiaofeng, Long, Xiaochun, Duque, Juan C, Salman, Loay H, Tabbara, Marwan, Martinez, Laisel, Vazquez-Padron, Roberto I

“…Arteries and veins develop different types of occlusive diseases and respond differently to injury. The biological reasons for this discrepancy are not well…”
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Unexpanded and intermediate CAG polymorphisms at the SCA2 locus (ATXN2) in the Cuban population: evidence about the origin of expanded SCA2 alleles by MIGUEL LAFFITA-MESA, José, VELAZQUEZ-PEREZ, Luis C, SANTOS FALCON, Nieves, CRUZ-MARINO, Tania, GONZALEZ ZALDIVAR, Yanetza, VAZQUEZ MOJENA, Yaimee, ALMAGUER-GOTAY, Dennis, ALMAGUER MEDEROS, Luis Enrique, RODRIGUEZ LABRADA, Roberto

“…The role of short, large or intermediate normal alleles (ANs) of the ataxin-2 gene in generating expanded alleles (EAs) causing spinocerebellar ataxia type 2…”
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Abstract 15806: The Unique Cellular Ecosystem of the Human Basilic Vein: A Single-Cell Transcriptomic Analysis by Rojas, Miguel G, Martinez, Laisel, Pereira-Simon, Simone, Zigmond, Zachary, Santos Falcon, Nieves, Salama, Alghidak, Vazquez-Padron, Roberto I

“…IntroductionThe cells in veins that contribute to vascular disease have not been fully characterized. This study generated a cellular atlas of the human…”
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Abstract 149: Type Viii Collagen Increases The Risk Of Arteriovenous Fistula Failure In End-stage Kidney Disease Patients by Martinez, Laisel, Rojas, Miguel, Tabbara, Marwan, Pereira-Simon, Simone, Santos Falcon, Nieves, Rauf, Mohd A, Zigmond, Zachary, Vazquez Padron, Roberto I

“…IntroductionThe arteriovenous fistula (AVF) is the lifeline for patients with end-stage kidney disease (ESKD) requiring hemodialysis therapy. The mechanism of…”
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Transcriptomics of Human Arteriovenous Fistula Failure: Genes Associated With Nonmaturation by Martinez, Laisel, Tabbara, Marwan, Duque, Juan C., Selman, Guillermo, Falcon, Nieves Santos, Paez, Angela, Griswold, Anthony J., Ramos-Echazabal, Gioser, Hernandez, Diana R., Velazquez, Omaida C., Salman, Loay H., Vazquez-Padron, Roberto I.

“…Improving arteriovenous fistula (AVF) outcomes requires better understanding of the biology underlying maturation or failure. Our current knowledge of…”
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A Novel Genetic Model of Constitutively Active Integrin CD11b/CD18 by Martinez, Laisel, Li, Xiaobo, Ramos-Echazabal, Gioser, Faridi, Hafeez, Zigmond, Zachary M., Falcon, Nieves Santos, Hernandez, Diana R., Shehadeh, Serene A., Velazquez, Omaida C., Gupta, Vineet, Vazquez-Padron, Roberto I.

“…Pharmacological activation of integrin CD11b/CD18 (α M β 2 , Mac-1, CR3) shows anti-inflammatory benefits in a variety of animal models of human disease, and…”
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S100A12 Induce Pro‐inflammatory Response in Pulmonary Fibroblasts by Medina, Maria Elena Monzon, Santos‐Falcon, Nieves, Campos, MIchael

“…Abstract only Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by a chronic and irreversible airflow obstruction that is…”
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The intricate cellular ecosystem of human peripheral veins as revealed by single-cell transcriptomic analysis by Miguel G. Rojas, Zachary M. Zigmond, Simone Pereira-Simon, Nieves Santos Falcon, Maya Suresh Kumar, Filipe F. Stoyell-Conti, Christina Kosanovic, Anthony J. Griswold, Alghidak Salama, Xiaofeng Yang, Marwan Tabbara, Roberto I. Vazquez-Padron, Laisel Martinez

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Systemic Profile of Cytokines in Arteriovenous Fistula Patients and Their Associations with Maturation Failure by Martinez, Laisel, Perla, Mikael, Tabbara, Marwan, Duque, Juan C, Rojas, Miguel G, Falcon, Nieves Santos, Pereira-Simon, Simone, Salman, Loay H, Vazquez-Padron, Roberto I

“…Systemic cytokines are elevated in patients with chronic kidney disease (CKD) and on hemodialysis compared with the general population. However, whether…”
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Epidemiología de la ataxia hereditaria cubana by Velázquez Pérez, Luis, Santos Falcón, Nieves, García Zaldivar, Reynaldo, Paneque Herrera, Milena, Hechavarría Pupo, Ricardo

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Caracterización clínico epidemiológica del acné conglobata en las provincias de Holguín y Granma by Raquel Rojas Bruzón, Guillermo Martínez Valdez, Nieves Santos Falcon, Luis Mederos Almaguer, Víctor Tamayo Chang, Juana Álvarez Ocampo

“…Introducción: el acné es una de las afecciones dermatológicas más frecuentes en la práctica médica, de ellas, el acné conglobata se caracteriza por ser poco…”
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Manifestaciones disautonómicas en pacientes de ataxia espinocerebelosa tipo 2 cubana by Sánchez Cruz, Gilberto, Velázquez Pérez, Luis, Gómez Peña, Luis, Martínez Góngora, Edilberto, Castellano Sánchez, Geovanis, Santos Falcón, Nieves

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