Search Results - "Santos, Wilson C."

Clinical trials on drug repositioning for COVID-19 treatment by Rosa, Sandro G Viveiros, Santos, Wilson C

“…The World Health Organization (WHO) was informed on December 2019 about a coronavirus pneumonia outbreak in Wuhan, Hubei province (China). Subsequently, on…”
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Microwave Assisted Synthesis of 4-Phenylquinazolin-2(1H)-one Derivatives that Inhibit Vasopressor Tonus in Rat Thoracic Aorta by Teixeira, Rafaela, Menengat, Talita, Andrade, Gabriel, Cotrim, Bruno, Ponte, Cristiano, Santos, Wilson C, Resende, Gabriel

“…Quinazolinones have pharmacological effects on vascular reactivity through different mechanisms. We synthesized 4-phenylquinazolin-2(1H)-one derivatives under…”
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Vector competence of Culex mosquitoes (Diptera: Culicidae) in Zika virus transmission: an integrative review by Viveiros-Rosa, Sandro G, Regis, Eduardo G, Santos, Wilson C

“…To identify studies on the competence of mosquitoes as vectors for the transmission of Zika virus (ZIKV) around the globe. We performed an integrative review…”
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Punica granatum L. Hydrogel for Wound Care Treatment: From Case Study to Phytomedicine Standardization by Fleck, Aline, Cabral, Patrik F G, Vieira, Felipe F M, Pinheiro, Deo A, Pereira, Carlos R, Santos, Wilson C, Machado, Thelma B

“…The pharmacological activities of many Punica granatum L. components suggest a wide range of clinical applications for the prevention and treatment of diseases…”
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Repositioning and investigational drugs for Zika virus infection treatment: a patent review by G Viveiros Rosa, Sandro, Fierro, Iolanda M, C Santos, Wilson

“…Zika virus (ZIKV) is transmitted to humans throughout bites of mosquitoes. ZIKV infection may be asymptomatic in most cases, but it may cause fever, headache,…”
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Remdesivir: an overview of patenting trends, clinical evidence on COVID-19 treatment, pharmacology and chemistry by Viveiros Rosa, Sandro G, Santos, Wilson C

“…By December 2021, the COVID-19 caused approximately 6.1 million deaths around the world. Several vaccines have been approved, but there is still a need for…”
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Vaccines and treatments for Zika virus infection: patent status, triumphs and challenges by Viveiros Rosa, Sandro G, Santos, Wilson C

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Quantitative determination of pentacyclic triterpenic acids in Amazonian species Eugenia punicifolia DC by ATR-FTIR by Albuquerque, Raphael P., Duarte, Glauce C. A., Duarte, Nelise, Ohana, Débora T., Santos, Wilson C., Machado, Thelma B.

“…Leaf extracts from Eugenia punicifolia are rich in pentacyclic triterpenic acids (PTAs), especially barbinervic acid (BA), which is an important biomarker of…”
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Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases by da Rocha, David R., Santos, Wilson C., Lima, Emerson S., Ferreira, Vitor F.

“…Ten new 1,2,3-triazole glycoconjugates were synthesized from d-glucose and evaluated in in vitro assays for their ability to inhibit the enzyme α-glucosidase…”
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In vitro and in silico studies for barbinervic acid, a triterpene isolated from Eugenia punicifolia that inhibits vasopressor tone by Teixeira, Rafaela G. S., de Pascual, Ricardo, Lima-Araújo, Kátia G., de Brito, Monique A., de los Rios, Cristobal, do Carmo, Artur F., Gandía, Luis, Silva, Cláudia L. M., Machado, Thelma B., Santos, Wilson C.

“…We investigated the role of triterpene barbinervic acid from Eugenia punicifolia dichloromethane extract in vasopressor responses. Renal arteries were…”
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Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice by Leite, Paulo Emílio Correa, Gandía, Luís, de Pascual, Ricardo, Nanclares, Carmen, Colmena, Inés, Santos, Wilson C, Lagrota-Candido, Jussara, Quirico-Santos, Thereza

“…Abstract Amount evidence indicates that α7 nicotinic acetylcholine receptor (nAChRα7) activation reduces production of inflammatory mediators. This work aimed…”
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Synthesis of new 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones and cytotoxicity against cancer cell lines by da Rocha, David R, de Souza, Ana C G, Resende, Jackson A L C, Santos, Wilson C, dos Santos, Evelyne A, Pessoa, Cláudia, de Moraes, Manoel O, Costa-Lotufo, Letícia V, Montenegro, Raquel C, Ferreira, Vitor F

“…A synthetic method to obtain α- and β-pyran naphthoquinones 10 and 11 with a hydroxyl substituent on the aromatic ring was developed. Two series of α- and…”
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Selective activation of alpha 7 nicotinic acetylcholine receptor (nAChR alpha 7) inhibits muscular degeneration in mdx dystrophic mice by Leite, Paulo Emilio Correa, Gandia, Luis, de Pascual, Ricardo, Nanclares, Carmen, Colmena, Ines, Santos, Wilson C, Lagrota-Candido, Jussara, Quirico-Santos, Thereza

“…Amount evidence indicates that alpha 7 nicotinic acetylcholine receptor (nAChR alpha 7) activation reduces production of inflammatory mediators. This work…”
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Implant of Polymer Containing Pentacyclic Triterpenes from Eugenia punicifolia Inhibits Inflammation and Activates Skeletal Muscle Remodeling by Leite, Paulo Emílio C., Lima-Araújo, Katia G., França, Guilherme R., Lagrota-Candido, Jussara, Santos, Wilson C., Quirico-Santos, Thereza

“…Sustained chronic inflammation induces activation of genes involved in cellular proliferation and apoptosis, thereby causing skeletal muscle degeneration. To…”
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Erratum to: Implant of Polymer Containing Pentacyclic Triterpenes from Eugenia punicifolia Inhibits Inflammation and Activates Skeletal Muscle Remodeling by Leite, Paulo Emílio C., Lima-Araújo, Katia G., França, Guilherme R., Lagrota-Candido, Jussara, Santos, Wilson C., Quirico-Santos, Thereza

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Anti-inflammatory activity of Eugenia punicifolia extract on muscular lesion of mdx dystrophic mice by Leite, Paulo Emílio Corrêa, de Almeida, Kessiane Belshoff, Lagrota-Candido, Jussara, Trindade, Pablo, da Silva, Rafael Ferreira, Ribeiro, Manuel Gustavo L., Lima-Araújo, Katia G., Santos, Wilson C., Quirico-Santos, Thereza

“…Eugenia punicifolia known as “pedra‐ume caá” is a shrub largely distributed in the Amazon region popularly used in decoctions or infusions as a natural…”
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l-NAME pre-treatment partially inhibits the agmatine-evoked depression of the electrically induced twitch contraction of isolated rat vas deferens by Garcez-do-Carmo, Lúcia, Santos, Wilson C.

“…The effect of the putative endogenous ligand for α 2-adrenoceptors and imidazoline receptors agmatine was studied in sympathetic neurotransmission in the rat…”
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Pharmacological effects of Eugenia punicifolia (Myrtaceae) in cholinergic nicotinic neurotransmission by Grangeiro, Marcielli Silva, Calheiros-Lima, Ana Paula, Martins, Manoel Francisco, Arruda, Luis Frederico, Garcez-do-Carmo, Lúcia, Santos, Wilson C.

“…The effects of the aqueous crude extract (5%) of Eugenia punicifolia on cholinergic nicotinic neurotransmission were investigated. Actions of aqueous crude…”
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Advances in drug discovery to assess cholinergic neurotransmission: a systematic review by Ferreira, Vitor F, da Rocha, David R, Lima Araújo, Kátia G, Santos, Wilson C

“…Neurotransmission is essential to physiological processes of cellular communication. The search for new molecules that may influence neurotransmission systems…”
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Competencia de los mosquitos Culex como vectores en la transmision del virus del Zika: una revision integradora by Viveiros-Rosa, Sandro G, Regis, Eduardo G, Santos, Wilson C

“…Métodos. Se realizó una revisión integradora para identificar artículos relevantes sobre experimentos específicos dirigidos a determinar si los mosquitos Culex…”
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