Search Results - "Santos, Rodrigo L.S.R."
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A novel μ-oxo-diruthenium(III,III)-ibuprofen-(4-aminopyridine) chloride derived from the diruthenium(II,III)-ibuprofen paddlewheel metallodrug shows anticancer properties
Published in Journal of inorganic biochemistry (01-12-2021)“…Diruthenium(II,III) metal-metal multiply bonded paddlewheel complexes bearing non-steroidal anti-inflammatory drugs are promising anticancer metallodrugs. The…”
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Synthesis and characterization of a diruthenium(II,III)–ketoprofen compound and study of the in vitro effects on CRC cells in comparison to the naproxen and ibuprofen derivatives
Published in Polyhedron (25-07-2012)“…A novel diruthenium(II,III)–ketoprofen metallodrug has been synthesized and mainly characterized by electrospray ionization mass spectrometry (ESI-MS),…”
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Growth inhibitory effects of the Diruthenium-Ibuprofen compound, [Ru2Cl(Ibp)4], in human glioma cells in vitro and in the rat C6 orthotopic glioma in vivo
Published in Journal of biological inorganic chemistry (01-08-2014)“…The Diruthenium-Ibuprofen compound [Ru 2 Cl(Ibp) 4 ] (or RuIbp) is known to cause significant inhibition of C6 rat glioma cell proliferation in vitro. RuIbp…”
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Thermodynamics of Axial Substitution and Kinetics of Reactions with Amino Acids for the Paddlewheel Complex Tetrakis(acetato)chloridodiruthenium(II,III)
Published in Inorganic chemistry (18-06-2012)“…The known paddlewheel, tetrakis(acetato)chloridodiruthenium(II,III), offers a versatile synthetic route to a novel class of antitumor diruthenium(II,III)…”
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