Search Results - "Santos, Ney P.C"
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Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel
Published in Human mutation (01-02-2010)“…Estimating the proportions of different ancestries in admixed populations is very important in population genetics studies, and it is particularly important…”
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Amerindian genetic ancestry and INDEL polymorphisms associated with susceptibility of childhood B-cell Leukemia in an admixed population from the Brazilian Amazon
Published in Leukemia research (01-11-2015)“…Highlights • The INDEL polymorphism in CASP8 is associated with decreasing chances of developing B-cell ALL. • The INDEL polymorphism in CYP19A1 is associated…”
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Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population
Published in Molecular genetics & genomic medicine (01-07-2021)“…Background Susceptibility to Chronic Myeloid Leukemia (CML) may be modulated by genetic variables. However, the majority of previous investigations have…”
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Analysis of 12 variants in the development of gastric and colorectal cancers
Published in World journal of gastroenterology : WJG (28-12-2017)“…AIM To evaluate the relation between 12 polymorphisms and the development of gastric cancer(GC) and colorectal cancer(CRC).METHODS In this study,we included…”
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The Search for Cancer Biomarkers: Assessing the Distribution of INDEL Markers in Different Genetic Ancestries
Published in Current issues in molecular biology (19-05-2022)“…Cancer is a multifactorial group of diseases, being highly incident and one of the leading causes of death worldwide. In Brazil, there is a great variation in…”
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The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review
Published in Genes (28-02-2020)“…the gene is clinically important and is known to have a number of variants. This gene has four distinct metabolization profiles that are determined by the…”
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UGT1A1 Gene Polymorphism Contributes as a Risk Factor for Lung Cancer: A Pilot Study with Patients from the Amazon
Published in Genes (11-03-2022)“…Lung cancer is one of the most frequent neoplasms in the world. Because it is a complex disease, its formation occurs in several stages, stemming from…”
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Exome Evaluation of Autism-Associated Genes in Amazon American Populations
Published in Genes (18-02-2022)“…Autism spectrum disorder is a neurodevelopmental disorder, affecting one in 160 children worldwide. The causes of autism are still poorly understood, but…”
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Estimating Asian Contribution to the Brazilian Population: A New Application of a Validated Set of 61 Ancestry Informative Markers
Published in G3 : genes - genomes - genetics (01-11-2018)“…Estimates of different ancestral proportions in admixed populations are very important in population genetics studies, especially for the detection of…”
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Distribution of allelic and genotypic frequencies of IL1A, IL4, NFKB1 and PAR1 variants in Native American, African, European and Brazilian populations
Published in BMC research notes (16-02-2016)“…The inflammatory response plays a key role at different stages of cancer development. Allelic variants of the interleukin 1A (IL1A), interleukin 4 (IL4),…”
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Influence of Polymorphism on the NFkB1 Gene (rs28362491) on the Susceptibility to Sarcopenia in the Elderly of the Brazilian Amazon
Published in Journal of personalized medicine (19-10-2021)“…Background: Sarcopenia is a disease characterized by progressive reduction in muscle mass and strength or function. Although it is known that sarcopenia may be…”
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X-linked insertion/deletion polymorphisms: forensic applications of a 33-markers panel
Published in International journal of legal medicine (01-11-2010)Get full text
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