Search Results - "Santos, Neife A.G."
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Carvedilol efficiently protects kidneys without affecting the antitumor efficacy of cisplatin in mice
Published in Chemico-biological interactions (25-10-2013)“…•Carvedilol protects against the nephrotoxicity of cisplatin in tumor-bearing mice.•Carvedilol does not affect the antitumor activity of cisplatin.•The…”
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Effect of diabetes on biodistribution, nephrotoxicity and antitumor activity of cisplatin in mice
Published in Chemico-biological interactions (05-03-2015)“…•A mouse model bearing a tumor, diabetes and nephrotoxicity was developed.•Diabetes decreases the platinum accumulation in multiple organs and tumor.•Diabetes…”
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Carvedilol protects the kidneys of tumor-bearing mice without impairing the biodistribution or the genotoxicity of cisplatin
Published in Chemico-biological interactions (05-02-2016)“…Cisplatin (Cisp) is an effective antitumor drug; however, it causes severe nephrotoxicity. Minimization of renal toxicity is essential, but the interference of…”
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A synthetic snake-venom-based tripeptide (Glu-Val-Trp) protects PC12 cells from MPP+ toxicity by activating the NGF-signaling pathway
Published in Peptides (New York, N.Y. : 1980) (01-06-2018)“…•A synthetic analogue (p-BTX-I) of a snake venom peptide mimics NGF in PC12 cells.•p-BTX-I increases neuritogenesis and viability of PC12 cells exposed to…”
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A Synthetic Snake-Venom-Based Tripeptide Protects PC12 Cells from the Neurotoxicity of Acrolein by Improving Axonal Plasticity and Bioenergetics
Published in Neurotoxicity research (2020)“…The synthetic peptide p-BTX-I is based on the native peptide (formed by glutamic acid, valine and tryptophan) isolated from Bothrops atrox venom. We have…”
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Effects of C-Terminal-Ethyl-Esterification in a Snake-Venom-Based Peptide Against the Neurotoxicity of Acrolein in PC12 Cells
Published in International journal of peptide research and therapeutics (03-04-2023)“…We have recently reported the neurotrophic and neuroprotective effects of the snake-venom-based synthetic tripeptide BTX-I in PC12 cells treated with acrolein…”
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Effects of Caffeic acid phenethyl ester on rat brain isolated mitochondria
Published in Toxicology letters (17-06-2012)Get full text
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A highly sensitive LC–MS–MS assay for analysis of midazolam and its major metabolite in human plasma: Applications to drug metabolism
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-08-2005)“…The present report describes a rapid, selective and a highly sensitive assay for midazolam (MDZ) and its major metabolite 1-hydroxymidazolam (1-OH-MDZ) in…”
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Herbicide leaching on a recharge area of the Guarany aquifer in Brazil
Published in Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes (2005)“…The region of Ribeirão Preto City, located in Southeast of Brazil, São Paulo State, is an important sugarcane, soybean, and corn producing area with a high…”
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Hg(II)-induced renal cytotoxicity: in vitro and in vivo implications for the bioenergetic and oxidative status of mitochondria
Published in Molecular and cellular biochemistry (01-12-1997)“…The effects of Hg(II) on bioenergetic and oxidative status of rat renal cortex mitochondria were evaluated both in vitro, and in vivo 1 and 24 h after…”
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