Search Results - "Santos, Marina I"

Vascularization in Bone Tissue Engineering: Physiology, Current Strategies, Major Hurdles and Future Challenges by Santos, Marina I., Reis, Rui L.

“…The lack of a functional vascular supply has, to a large extent, hampered the whole range of clinical applications of ‘successful’ laboratory‐based bone tissue…”
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Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone–starch scaffold and the in vitro development of vascularization by Santos, Marina I, Unger, Ronald E, Sousa, Rui A, Reis, Rui L, Kirkpatrick, C. James

“…Abstract The reconstruction of bone defects based on cell-seeded constructs requires a functional microvasculature that meets the metabolic demands of the…”
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Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering by Santos, Marina I, Tuzlakoglu, Kadriye, Fuchs, Sabine, Gomes, Manuela E, Peters, Kirsten, Unger, Ronald E, Piskin, Erhan, Reis, Rui L, Kirkpatrick, C. James

“…Abstract Presently the majority of tissue engineering approaches aimed at regenerating bone relies only on post-implantation vascularization. Strategies that…”
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Design of nano- and microfiber combined scaffolds by electrospinning of collagen onto starch-based fiber meshes: a man-made equivalent of natural extracellular matrix by Tuzlakoglu, Kadriye, Santos, Marina I, Neves, Nuno, Reis, Rui L

“…Mimicking the structural organization and biologic function of natural extracellular matrix has been one of the main goals of tissue engineering. Nevertheless,…”
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Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering by Santos, Marina I, Fuchs, Sabine, Gomes, Manuela E, Unger, Ronald E, Reis, Rui L, Kirkpatrick, C. James

“…Abstract The establishment of a functional vasculature is as yet an unrealized milestone in bone reconstruction therapy. For this study, fiber-mesh scaffolds…”
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Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications by Martins, Ana M., Santos, Marina I., Azevedo, Helena S., Malafaya, Patricia B., Reis, Rui L.

“…This work describes the development of a biodegradable matrix, based on chitosan and starch, with the ability to form a porous structure in situ due to the…”
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