Search Results - "Santos, Leonilda M. B."

Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis by von Glehn, Felipe, Pochet, Nathalie, Thapa, Bibek, Raheja, Radhika, Mazzola, Maria A, Jangi, Sushrut, Beynon, Vanessa, Huang, Junning, Farias, Alessandro S, Paul, Anu, Santos, Leonilda M B, Gandhi, Roopali, Murugaiyan, Gopal, Weiner, Howard L, Baecher-Allan, Clare M

“…The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become…”
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Structural brain abnormalities are related to retinal nerve fiber layer thinning and disease duration in neuromyelitis optica spectrum disorders by von Glehn, Felipe, Jarius, Sven, Cavalcanti Lira, Rodrigo Pessoa, Alves Ferreira, Maria Carolina, von Glehn, Fadua H Ribeiro, Costa e Castro, Stella Maris, Beltramini, Guilherme Coco, Bergo, Felipe PG, Farias, Alessandro S, Brandão, Carlos Otávio, Wildemann, Brigitte, Damasceno, Benito P, Cendes, Fernando, Santos, Leonilda M B, Yasuda, Clarissa Lin

“…Background: Although aquaporin-4 (AQP4) is widely expressed in the human brain cortex, lesions are rare in neuromyelitis optica (NMO) spectrum disorders…”
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Cytotoxic profile of CD3+CD20+ T cells in progressive multiple sclerosis by Boldrini, Vinícius O., Quintiliano, Raphael P. S., Silva, Lucas S., Damasceno, Alfredo, Santos, Leonilda M. B., Farias, Alessandro S.

“…Recently, it was shown that highly effective anti-CD20 therapies used for MS patients not only deplete CD20+ B cells, but also a small subset of T cells…”
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Vitamin D3 Induces IDO+ Tolerogenic DCs and Enhances Treg, Reducing the Severity of EAE by Farias, Alessandro S., Spagnol, Gabriela S., Bordeaux‐Rego, Pedro, Oliveira, Camila O.F., Fontana, Ana Gabriela M., Paula, Rosemeire F.O., Santos, Mariana P.A., Pradella, Fernando, Moraes, Adriel S., Oliveira, Elaine C., Longhini, Ana Leda F., Rezende, Alexandre C.S., Vaisberg, Mauro W., Santos, Leonilda M.B.

“…Summary Background A growing body of evidence supports the hypothesis that vitamin D is an important environmental factor in the etiology of T‐cell‐mediated…”
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Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis by Farias, Alessandro S, Talaisys, Rafael L, Blanco, Yara C, Lopes, Stefanie C P, Longhini, Ana Leda F, Pradella, Fernando, Santos, Leonilda M B, Costa, Fabio T M

“…Experimental autoimmune encephalomyelitis (EAE) is used as an animal model for human multiple sclerosis (MS), which is an inflammatory demyelinating autoimmune…”
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Disappearance of cerebrospinal fluid oligoclonal bands after natalizumab treatment of multiple sclerosis patients by von Glehn, Felipe, Farias, Alessandro S, de Oliveira, Augusto C Penalva, Damasceno, Alfredo, Longhini, Ana Leda F, Oliveira, Elaine C, Damasceno, Benito P, Santos, Leonilda MB, Brandão, Carlos Otávio

“…Intrathecal immunoglobulin synthesis in an oligoclonal pattern is the most common immunologic abnormality detected in MS patients. Various treatments, such as…”
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Proteome analysis of spinal cord during the clinical course of monophasic experimental autoimmune encephalomyelitis by Farias, Alessandro S., Martins-de-Souza, Daniel, Guimarães, Leandro, Pradella, Fernando, Moraes, Adriel S., Facchini, Gustavo, Novello, José Camillo, Santos, Leonilda M. B.

“…The induction of autoimmune encephalomyelitis (EAE) in Lewis rats results in a period of exacerbation followed by complete recovery. Therefore, this model is…”
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Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy by von Glehn, Felipe, Jarius, Sven, Penalva de Oliveira, Augusto C, Brandão, Carlos Otávio, Farias, Alessandro S, Damasceno, Alfredo, Casseb, Jorge, Moraes, Adriel S, Longhini, Ana Leda F, Wandinger, Klaus-Peter, Damasceno, Benito P, Wildemann, Brigitte, Santos, Leonilda M B

“…The seroprevalence of human T-cell leukemia virus type 1 (HTLV-1) is very high among Brazilians (1:200). HTLV-1 associated myelopathy or tropical spastic…”
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Lymphocyte activation in silica-exposed workers by Rocha-Parise, Michelle, Santos, Leonilda M.B., Damoiseaux, Jan G.M.C., Bagatin, Ericson, Lido, Alessandro V., Torello, Cristiane Okuda, Cohen Tervaert, Jan W., Queiroz, Mary L.S.

“…Exposure to silica dust has been examined as a possible risk factor for autoimmune diseases, including systemic sclerosis, rheumatoid arthritis, systemic lupus…”
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The Suppressive Effect of IL‐27 on Encephalitogenic Th17 Cells Induced by Multiwalled Carbon Nanotubes Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Moraes, Adriel S., Paula, Rosemeire F.O., Pradella, Fernando, Santos, Mariana P.A., Oliveira, Elaine C., Glehn, Felipe, Camilo, Daniela S., Ceragioli, Helder, Peterlevitz, Alfredo, Baranauskas, Vitor, Volpini, Walkyria, Farias, Alessandro S., Santos, Leonilda M.B.

“…Summary Background Both Th1 and Th17 cells specific for neuroantigen are described as encephalitogenic in the experimental autoimmune encephalomyelitis (EAE)…”
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Impact of pregabalin treatment on synaptic plasticity and glial reactivity during the course of experimental autoimmune encephalomyelitis by Silva, Gleidy A. A., Pradella, Fernando, Moraes, Adriel, Farias, Alessandro, Santos, Leonilda M. B., Oliveira, Alexandre L. R.

“…Background Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease that affects young adults. It is characterized by generating a chronic…”
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Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse by Longhini, Ana Leda F, von Glehn, Felipe, Brandão, Carlos Otávio, de Paula, Rosemeire F O, Pradella, Fernando, Moraes, Adriel S, Farias, Alessandro S, Oliveira, Elaine C, Quispe-Cabanillas, Juan G, Abreu, Cassiana Horta, Damasceno, Alfredo, Damasceno, Benito P, Balashov, Konstantin E, Santos, Leonilda M B

“…The plasmacytoid dendritic cells (pDCs) express a high level of Toll-like receptor 9 (TLR-9), which recognizes viral DNA. Activated via TLR-9, pDCs also…”
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Hyperbaric oxygen prevents early death caused by experimental cerebral malaria by Blanco, Yara C, Farias, Alessandro S, Goelnitz, Uta, Lopes, Stefanie C P, Arrais-Silva, Wagner W, Carvalho, Bruna O, Amino, Rogério, Wunderlich, Gerhard, Santos, Leonilda M B, Giorgio, Selma, Costa, Fabio T M

“…Cerebral malaria (CM) is a syndrome characterized by neurological signs, seizures and coma. Despite the fact that CM presents similarities with cerebral…”
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Dimethyl fumarate modulates the regulatory T cell response in the mesenteric lymph nodes of mice with experimental autoimmune encephalomyelitis by Lima, Amanda D R, Ferrari, Breno B, Pradella, Fernando, Carvalho, Rodrigo M, Rivero, Sandra L S, Quintiliano, Raphael P S, Souza, Matheus A, Brunetti, Natália S, Marques, Ana M, Santos, Irene P, Farias, Alessandro S, Oliveira, Elaine C, Santos, Leonilda M B

“…Dimethyl fumarate (DMF, Tecfidera) is an oral drug utilized to treat relapsing-remitting multiple sclerosis (MS). DMF treatment reduces disease activity in MS…”
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Cytotoxic B Cells in Relapsing-Remitting Multiple Sclerosis Patients by Boldrini, Vinícius O, Marques, Ana M, Quintiliano, Raphael P S, Moraes, Adriel S, Stella, Carla R A V, Longhini, Ana Leda F, Santos, Irene, Andrade, Marília, Ferrari, Breno, Damasceno, Alfredo, Carneiro, Rafael P D, Brandão, Carlos Otávio, Farias, Alessandro S, Santos, Leonilda M B

“…Emerging evidence of antibody-independent functions, as well as the clinical efficacy of anti-CD20 depleting therapies, helped to reassess the contribution of…”
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Interferon-beta modifies the peripheral blood cell cytokine secretion in patients with multiple sclerosis by Mirandola, Sandra R., Hallal, Dannie E.M., Farias, Alessandro S., Oliveira, Elaine C., Brandão, Carlos O., Ruocco, Heloisa H., Damasceno, Benito P., Santos, Leonilda M.B.

“…Immunotherapy with Interferon-beta (IFNβ) results in remarkably beneficial effects in patients with relapsing-remitting multiple sclerosis (MS), although the…”
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Ten years of proteomics in multiple sclerosis by Farias, Alessandro S., Pradella, Fernando, Schmitt, Andrea, Santos, Leonilda M. B., Martins-de-Souza, Daniel

“…Multiple sclerosis, which is the most common cause of chronic neurological disability in young adults, is an inflammatory, demyelinating, and neurodegenerative…”
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In vivo Administration of TLR9 Agonist Reduces the Severity of Experimental Autoimmune Encephalomyelitis. The Role of Plasmacytoid Dendritic Cells and B Lymphocytes by Longhini, Ana Leda F., Santos, Mariana P. A., Pradella, Fernando, Moraes, Adriel S., Dionete, Alliny C., Andrade, Marilia D., Russini, Paula G., Oliveira, Elaine C., Paula, Rosemeire O. F., Morais, Guilherme A. D., Fonseca, Evelise S. M., Farias, Alessandro S., Santos, Leonilda M. B.

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Decreased Neurofilament L Chain Levels in Cerebrospinal Fluid and Tolerogenic Plasmacytoid Dendritic Cells in Natalizumab-Treated Multiple Sclerosis Patients – Brief Research Report by Moraes, Adriel S., Boldrini, Vinicius O., Dionete, Alliny C., Andrade, Marilia D., Longhini, Ana Leda F., Santos, Irene, Lima, Amanda D. R., Silva, Veronica A. P. G., Dias Carneiro, Rafael P. C., Quintiliano, Raphael P. S., Ferrari, Breno B., Damasceno, Alfredo, Pradella, Fernando, Farias, Alessandro S., Tilbery, Charles P., Domingues, Renan B., Senne, Carlos, Fernandes, Gustavo B. P., von Glehn, Felipe, Brandão, Carlos Otavio, Stella, Carla R. A. V., Santos, Leonilda M. B.

“…Background Neurofilament Light (NfL) chain levels in both cerebrospinal fluid (CSF) and serum have been correlated with the reduction of axonal damage in…”
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The effect of treatment with crotapotin on the evolution of experimental autoimmune neuritis induced in Lewis rats by Castro, Fabiano R., Farias, Alessandro S., Proença, Patricia L.F., de La Hoz, Cristiane, Langone, Francesco, Oliveira, Elaine C., Toyama, Marcos H., Marangoni, Sergio, Santos, Leonilda M.B.

“…Biomedical research in which venom components are being investigated for their potential as novel therapeutic agents has emerged as an interesting option…”
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