Search Results - "Santos, Jose S."
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Piezo1 Channels Are Inherently Mechanosensitive
Published in Cell reports (Cambridge) (08-11-2016)“…The conversion of mechanical force to chemical signals is critical for many biological processes, including the senses of touch, pain, and hearing…”
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2
Modulation of lipase B from Candida antarctica properties via covalent immobilization on eco-friendly support for enzymatic kinetic resolution of rac-indanyl acetate
Published in Bioprocess and biosystems engineering (01-12-2020)“…In this study, the modulation of enzymatic biocatalysts were developed by the use of lipase B from Candida antarctica covalently immobilized on an eco-friendly…”
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3
Operational and Thermal Stability Analysis of Thermomyces lanuginosus Lipase Covalently Immobilized onto Modified Chitosan Supports
Published in Applied biochemistry and biotechnology (2018)“…The aim of this paper was to evaluate different strategies of chitosan activation using cross-linking reagent like glycidol, epichlorohydrin, and…”
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Synthesis of Benzyl Acetate Catalyzed by Lipase Immobilized in Nontoxic Chitosan-Polyphosphate Beads
Published in Molecules (Basel, Switzerland) (07-12-2017)“…Enzymes serve as biocatalysts for innumerable important reactions, however, their application has limitations, which can in many cases be overcome by using…”
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CA-CFAR Detection for SAR Systems Over Correlated Gamma-Distributed Clutter
Published in IEEE geoscience and remote sensing letters (2024)“…In the context of synthetic aperture radar (SAR) systems, the Gamma distribution stands out as a strong contender for clutter modeling. The cell-averaging…”
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6
CA-CFAR Detection Performance in Homogeneous Weibull Clutter
Published in IEEE geoscience and remote sensing letters (01-06-2019)“…This letter presents a novel and exact formulation for the probability of detection of a cell-averaging, constant false-alarm rate (CFAR) radar system…”
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Importance of the Support Properties for Immobilization or Purification of Enzymes
Published in ChemCatChem (17-08-2015)“…Immobilization and purification of enzymes are usual requirements for their industrial use. Both purification and immobilization have a common factor: they use…”
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Tetrameric assembly of KvLm K⁺ channels with defined numbers of voltage sensors
Published in Proceedings of the National Academy of Sciences - PNAS (16-10-2012)“…Voltage-gated K ⁺ (Kv) channels are tetrameric assemblies in which each modular subunit consists of a voltage sensor and a pore domain. KvLm, the voltage-gated…”
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Sonohydrolysis using an enzymatic cocktail in the preparation of free fatty acid
Published in 3 Biotech (01-06-2020)“…In this work, the concept of lipase cocktail has been proposed in the ultrasound-assisted hydrolysis of coconut oil. Lipase from Thermomyces lanuginosus (TLL),…”
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10
Botulinum neurotoxin heavy chain belt as an intramolecular chaperone for the light chain
Published in PLoS pathogens (01-09-2007)“…[...]SNARE proteolysis destabilizes or prevents full assembly of the SNARE core complex, abrogating fusion of synaptic vesicles with the plasma membrane,…”
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11
L-Methionine inhibits growth of human pancreatic cancer cells
Published in Anti-cancer drugs (01-02-2014)“…We have previously shown that L-methionine inhibits proliferation of breast, prostate, and colon cancer cells. This study extends these findings to BXPC-3…”
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12
Piezo proteins are pore-forming subunits of mechanically activated channels
Published in Nature (London) (08-03-2012)“…Mechanotransduction has an important role in physiology. Biological processes including sensing touch and sound waves require as-yet-unidentified cation…”
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13
Chemical Modification in the Design of Immobilized Enzyme Biocatalysts: Drawbacks and Opportunities
Published in Chemical record (01-06-2016)“…Chemical modification of enzymes and immobilization used to be considered as separate ways to improve enzyme properties. This review shows how the coupled use…”
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The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine
Published in The Journal of biological chemistry (05-02-2016)“…KCNQ (voltage-gated K+ channel family 7 (Kv7)) channels control cellular excitability and underlie the K+ current sensitive to muscarinic receptor signaling…”
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Strategies of covalent immobilization of a recombinant Candida antarctica lipase B on pore-expanded SBA-15 and its application in the kinetic resolution of (R,S)-Phenylethyl acetate
Published in Journal of molecular catalysis. B, Enzymatic (01-11-2016)“…[Display omitted] •LIPB was successfully immobilized on modified SBA-15 supports with DVS and GA.•Biocatalysts produced are more stable than…”
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CA-CFAR Performance in K-Distributed Sea Clutter with Fully Correlated Texture
Published in IEEE geoscience and remote sensing letters (01-01-2023)“…Sea clutter has been a long-standing issue in old and modern radars. Under this context, the K-distribution has emerged as a promising clutter model to…”
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The Chemistry and Applications of Metal–Organic Frameworks (MOFs) as Industrial Enzyme Immobilization Systems
Published in Molecules (Basel, Switzerland) (15-07-2022)“…Enzymatic biocatalysis is a sustainable technology. Enzymes are versatile and highly efficient biocatalysts, and have been widely employed due to their…”
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Reversible Immobilization of Lipases on Heterofunctional Octyl-Amino Agarose Beads Prevents Enzyme Desorption
Published in Molecules (Basel, Switzerland) (16-05-2016)“…Two different heterofunctional octyl-amino supports have been prepared using ethylenediamine and hexylendiamine (OCEDA and OCHDA) and utilized to immobilize…”
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Molecular template for a voltage sensor in a novel K+ channel. I. Identification and functional characterization of KvLm, a voltage-gated K+ channel from Listeria monocytogenes
Published in The Journal of general physiology (01-09-2006)“…The fundamental principles underlying voltage sensing, a hallmark feature of electrically excitable cells, are still enigmatic and the subject of intense…”
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Immobilization of Lipase A from Candida antarctica onto Chitosan-Coated Magnetic Nanoparticles
Published in International journal of molecular sciences (17-08-2019)“…In this communication, lipase A from (CALA) was immobilized by covalent bonding on magnetic nanoparticles coated with chitosan and activated with…”
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