Search Results - "Santos, Jennifer L"

Chemotherapy Response Score: Development and Validation of a System to Quantify Histopathologic Response to Neoadjuvant Chemotherapy in Tubo-Ovarian High-Grade Serous Carcinoma by Böhm, Steffen, Faruqi, Asma, Said, Ian, Lockley, Michelle, Brockbank, Elly, Jeyarajah, Arjun, Fitzpatrick, Amanda, Ennis, Darren, Dowe, Thomas, Santos, Jennifer L, Cook, Linda S, Tinker, Anna V, Le, Nhu D, Gilks, C Blake, Singh, Naveena

“…To develop and validate a histopathologic scoring system for measuring response to neoadjuvant chemotherapy in interval debulking surgery specimens of stage…”
Get full text

Differences in Tumor Type in Low-stage Versus High-stage Ovarian Carcinomas by Köbel, Martin, Kalloger, Steve E, Huntsman, David G, Santos, Jennifer L, Swenerton, Kenneth D, Seidman, Jeffrey D, Gilks, C Blake

“…Although there are recognized differences in the type of ovarian carcinomas between those tumors diagnosed at low versus high stage, there is a lack of data on…”
Get full text

Amplification of PVT1 Contributes to the Pathophysiology of Ovarian and Breast Cancer by YINGHUI GUAN, KUO, Wen-Lin, KALLOGER, Steve E, CARLSON, Joseph W, GINZINGER, David G, CELNIKER, Susan E, MILLS, Gordon B, HUNTSMAN, David G, GRAY, Joe W, STILWELL, Jackie L, TAKANO, Hirokuni, LAPUK, Anna V, FRIDLYAND, Jane, MAO, Jian-Hua, MAMIE YU, MILLER, Melinda A, SANTOS, Jennifer L

“…Purpose: This study was designed to elucidate the role of amplification at 8q24 in the pathophysiology of ovarian and breast cancer because increased copy…”
Get full text

Tumor type and substage predict survival in stage I and II ovarian carcinoma: Insights and implications by Köbel, Martin, Kalloger, Steve E, Santos, Jennifer L, Huntsman, David G, Gilks, C. Blake, Swenerton, Kenneth D

“…Abstract Objective An ability to predict survival is of crucial importance in determining the need for cancer therapy. Recent advances in tumor typing of…”
Get full text

Amplification of 11q13 in ovarian carcinoma by Brown, Lindsay A., Kalloger, Steve E., Miller, Melinda A., Shih, Ie-Ming, McKinney, Steven E., Santos, Jennifer L., Swenerton, Ken, Spellman, Paul T., Gray, Joe, Gilks, C. Blake, Huntsman, David G.

“…Amplification at the 11q13 locus is commonly observed in breast, ovarian, head and neck, oral, and esophageal cancer. Studies of this region led to the…”
Get full text

Early-stage endometrioid ovarian carcinoma: population-based outcomes in British Columbia by Kumar, Aalok, Le, Nhu, Tinker, Anna V, Santos, Jennifer L, Parsons, Christina, Hoskins, Paul J

“…Specific outcomes for early-stage ovarian endometrioid carcinoma (OEC) have not been well characterized. In addition, the benefit of any type of postsurgical…”
Get more information

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma by Prentice, Leah M, Klausen, Christian, Kalloger, Steve, Köbel, Martin, McKinney, Steven, Santos, Jennifer L, Kenney, Challayne, Mehl, Erika, Gilks, C Blake, Leung, Peter, Swenerton, Ken, Huntsman, David G, Aparicio, Samuel A J

“…Kisspeptins and their G-protein coupled receptor, GPR54 are required for GnRH release and have been associated with anti-metastatic tumour cell behaviour in…”
Get full text

Too Much Too Late? Chemotherapy Administration at the End of Life: A Retrospective Observational Study by Wilkerson, David H., Santos, Jennifer L., Tan, Xiyan, Gomez, Teny Henry

“…Purpose: Cancer treatment for those nearing death has become increasingly aggressive over time despite evidence that less aggressive approaches are associated…”
Get full text

Corrigendum to “Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes” [Gynecologic Oncology, Volume 157, Issue 1, April 2020, Pages 36–45] by Scott, Stephanie A., Fernandez, Marta Llaurado, Kim, Hannah, Elit, Laurie, Nourmoussavi, Melica, Glaze, Sarah, Roberts, Lesley, Offman, Saul L., Rahimi, Kurosh, Lytwyn, Alice, Sur, Monalisa, Gilks, C. Blake, Matheson, Kara, Köbel, Martin, Dawson, Amy, Tinker, Anna V., Kwon, Janice S., Hoskins, Paul, Santos, Jennifer L., Cheung, Andrea, Provencher, Diane, Carey, Mark S.

Get full text

Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes by Scott, Stephanie A., Llaurado Fernandez, Marta, Kim, Hannah, Elit, Laurie, Nourmoussavi, Melica, Glaze, Sarah, Roberts, Lesley, Offman, Saul L., Rahimi, Kurosh, Lytwyn, Alice, Sur, Monalisa, Gilks, C. Blake, Matheson, Kara, Köbel, Martin, Dawson, Amy, Tinker, Anna V., Kwon, Janice S., Hoskins, Paul, Santos, Jennifer L., Cheung, Andrea, Provencher, Diane, Carey, Mark S.

“…Patients with advanced low-grade serous carcinoma (LGSC) have poor long-term survival rates. As a rare histotype, there are uncertainties regarding the use of…”
Get full text

Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition by Lau, Tammy T.Y., May, Christina M., Sefid Dashti, Zahra J., Swanson, Lucas, Starks, Elizabeth R., Parker, Jeremy D.K., Moore, Richard A., Tucker, Tracy, Bosdet, Ian, Young, Sean S., Santos, Jennifer L., Compton, Katie, Heidary, Nili, Hoang, Lien, Schrader, Kasmintan A., Sun, Sophie, Kwon, Janice S., Tinker, Anna V., Karsan, Aly

“…Next-generation sequencing assays are capable of identifying cancer patients eligible for targeted therapies and can also detect germline variants associated…”
Get full text

Survival Benefit of Adjuvant Radiotherapy: An Analysis of Low-Stage Invasive Ovarian Mucinous Carcinomas by Kumar, Aalok, Le, Nhu, Gilks, C Blake, Santos, Jennifer L, Wong, Frances, Swenerton, Kenneth, Hoskins, Paul J, McAlpine, Jessica N, Tinker, Anna V

“…Our aim was to evaluate the population-based outcomes of stages I and II invasive ovarian mucinous carcinomas (MCs) treated with adjuvant platinum-based…”
Get more information

Stage II to IV Low-grade Serous Carcinoma of the Ovary Is Associated With a Poor Prognosis: A Clinicopathologic Study of 32 Patients From a Population-based Tumor Registry by Ali, Rola H, Kalloger, Steve E, Santos, Jennifer L, Swenerton, Kenneth D, Gilks, C Blake

“…Low-grade serous carcinoma (LGSC) of the ovary has only recently been recognized as a disease entity distinct from the more common high-grade serous carcinoma…”
Get full text

The impact of geographic variations in treatment on outcomes in ovarian cancer by Dehaeck, Ulrike, McGahan, Colleen E, Santos, Jennifer L, Carey, Mark S, Swenerton, Kenneth D, Kwon, Janice S

“…There are significant regional differences in survival outcomes across British Columbia among women with ovarian cancer. The age-adjusted hazard ratio for…”
Get more information

Tumor Type and Substage Predict Survival in Stage I and II Ovarian Carcinoma: Insights and Implications by Köbel, Martin, Kalloger, Steve E, Santos, Jennifer L, Huntsman, David G, Blake Gilks, C, Swenerton, Kenneth D

“…Tumor grade has been the most accepted prognostic indicator of disease-specific survival among women with stage I and II ovarian carcinomas. Many investigators…”
Get full text

Fungal histidine kinases by Santos, J L, Shiozaki, K

“…Eukaryotic cells predominantly use serine, threonine, and tyrosine phosphorylation in various intracellular signal transduction pathways. In contrast,…”
Get full text

Phosphorelay signaling in yeast in response to changes in osmolarity by Santos, Jennifer L, Shiozaki, Kazuhiro

“…In the yeast, Saccharomyces cerevesiae, phosphorelay signaling systems that involve a three-step His-Asp-His-Asp phosphotransfer are involved in transmitting…”
Get full text

Phosphorelay Signaling in Yeast in Response to Changes in Osmolarity by Santos, Jennifer L, Shiozaki, Kazuhiro

“…In the yeast, Saccharomyces cerevesiae, phosphorelay signaling systems that involve a three-step His-Asp-His-Asp phosphotransfer are involved in transmitting…”
Get full text