Search Results - "Santos, Hélio F. Dos"

Unveiling the Releasing Processes of Pt(II)-Based Anticancer Drugs from Oxidized Carbon Nanohorn: An In Silico Study by Almeida, Eduardo R., Capriles, Priscila V. S. Z., Dos Santos, Hélio F.

“…About half of all cancer chemotherapies currently applied involve medication with the three worldwide approved Pt­(II)-based drugs, cisplatin (cddp),…”
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Translocation Processes of Pt(II)-Based Drugs through Human Breast Cancer Cell Membrane: In Silico Experiments by Almeida, Eduardo R., Goliatt, Priscila V. Z. Capriles, Dos Santos, Hélio F., Picaud, Fabien

“…Breast cancer is one of the most frequent modalities of cancer worldwide, with notable mortality. The medication based on platinum drugs (cisplatin (cddp),…”
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Unveiling the Molecular Structure of Antimalarial Drugs Chloroquine and Hydroxychloroquine in Solution through Analysis of 1H NMR Chemical Shifts by Hernandes, Isabel S, Da Silva, Haroldo C, Dos Santos, Hélio F, De Almeida, Wagner B

“…Chloroquine (CQ) and hydroxychloroquine (HCQ) have been standard antimalarial drugs since the early 1950s, and very recently, the possibility of their use for…”
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Electron-Donor–Acceptor Complex-Enabled Flow Methodology for the Hydrotrifluoromethylation of Unsaturated β‑Keto Esters by Batista, Gabriel M. F, de Castro, Pedro P, Dos Santos, Hélio F, de Oliveira, Kleber T, Amarante, Giovanni W

“…A novel electron-donor–acceptor (EDA) complex-enabled flow photochemical hydrotrifluoromethylation of unsaturated β-keto esters is described. The developed…”
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Chemically Modified Carbon Nanohorns as Nanovectors of the Cisplatin Drug: A Molecular Dynamics Study by Almeida, Eduardo R, De Souza, Leonardo A, De Almeida, Wagner B, Dos Santos, Hélio F

“…Carbon nanohorns (CNH) have been considered potential anticancer drug carriers, such as the cisplatin drug (cddp), due to their low toxicity, high purity,…”
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Solvent Dependent Competitive Mechanisms for the Ugi Multicomponent Reaction: A Joint Theoretical and Experimental Study in the α‑Acyl Aminocarboxamides vs α‑Amino Amidines Formation by Carvalho, Marcelo H. R., Ribeiro, João P. R. S., De Castro, Pedro P., Passos, Saulo T. A., Neto, Brenno A. D., Dos Santos, Hélio F., Amarante, Giovanni W.

“…A synthetic protocol for the preparation of α-acyl aminocarboxamides and α-amino amidines is proposed. The selectivity toward each of these two possible…”
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Computational Prediction of Tc-99 NMR Chemical Shifts in Technetium Complexes with Radiopharmaceutical Applications by de Andrade, Taís F. C. B., Dos Santos, Hélio F., Fonseca Guerra, Célia, Paschoal, Diego F. S.

“…The Tc-99m nucleus is the most used nuclide in radiopharmaceuticals designed for imaging diagnosis. The metal can exist in nine distinct oxidation states and…”
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Origin of Enantioselectivity in Chiral Phosphoric-Acid-Catalyzed Azlactone Dynamic Kinetic Resolution by De Castro, Pedro P, Batista, Gabriel M. F, Amarante, Giovanni W, Dos Santos, Hélio F

“…Theoretical calculations, associated with control experiments, were carried out to gain insights into the mechanism and origin of enantioselectivity in the…”
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Inclusion complexes between cisplatin and oxidized carbon nanostructures: A theoretical approach by De Souza, Leonardo A., Dos Santos, Hélio F., Costa, Luciano T., De Almeida, Wagner B.

“…The toxicity of inclusion compounds formed by carbon nanostructures depends on its functionalized surface, use of solvents, dosage and other properties…”
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Quantum Chemical-Guided Steglich Rearrangement of Azlactones and Isoxazolones by De Castro, Pedro P, Dos Santos, Juliana A, De Siqueira, Marcelo M, Batista, Gabriel M. F, Dos Santos, Hélio F, Amarante, Giovanni W

“…The theoretical-guided evaluation of the Steglich rearrangement of azlactones and isoxazolones allowed the determination of the reactivity patterns in these…”
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On the Azo/Hydrazo Equilibrium in Sudan I Azo Dye Derivatives by Ferreira, Gilson R, Garcia, Humberto Costa, Couri, Mara Rubia C, Dos Santos, Hélio F, de Oliveira, Luiz Fernando C

“…In this study, Raman, infrared, UV/vis, NMR, and single crystal X-ray diffraction spectroscopies are used to elucidate the tautomeric equilibrium of azo dyes…”
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Vibrational frequencies and intramolecular force constants for cisplatin: assessing the role of the platinum basis set and relativistic effects by de Almeida, Caroline A., Pinto, Larissa P. N. M., Dos Santos, Hélio F., Paschoal, Diego F. S.

“…The role of platinum basis set (PTBS) and relativistic effects for predicting the vibrational frequencies and intramolecular force constants for cisplatin are…”
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Theoretical Study of the Formation of Inclusion Complex between Cisplatin and Single-Wall Carbon Nanotube by Souza, Leonardo A. De, Nogueira, Camila A.S, Lopes, Juliana F, Santos, Hélio F. Dos, Almeida, Wagner B. De

“…We report theoretical quantum chemical design and investigation of supramolecular structures formed by cisplatin and a single-wall carbon nanotube (SWCNT)…”
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Determination of Anticancer Zn(II)–Rutin Complex Structures in Solution through Density Functional Theory Calculations of 1H NMR and UV–VIS Spectra by Da Silva, Haroldo C, De Souza, Leonardo A, Dos Santos, Hélio F, De Almeida, Wagner B

“…Coordination compounds formed by flavonoid ligands are recognized as promising candidates as novel drugs with enhanced antioxidant and anticancer activity…”
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SPECTROSCOPIC CHARACTERIZATION OF PEDOT:PSS CONDUCTING POLYMER BY RESONANCE RAMAN AND SERRS SPECTROSCOPIES by Almeida, Pedro, Izumi, Celly, Santos, Hélio, Sant’Ana, Antonio C

“…Poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) synthesis was monitored by resonance Raman (RR) and surface-enhanced resonance Raman…”
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Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors by Tunes, Luiza G, Morato, Roberta E, Garcia, Adriana, Schmitz, Vinicius, Steindel, Mario, Corrêa-Junior, José D, Dos Santos, Hélio F, Frézard, Frédéric, de Almeida, Mauro V, Silva, Heveline, Moretti, Nilmar S, de Barros, André L. B, do Monte-Neto, Rubens L

“…The drugs currently used to treat leishmaniases have limitations concerning cost, efficacy, and safety, making the search for new therapeutic approaches…”
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Spectroscopic and Theoretical Study of the “Azo”-Dye E124 in Condensate Phase: Evidence of a Dominant Hydrazo Form by Almeida, Mariana R, Stephani, Rodrigo, Dos Santos, Hélio F, Oliveira, Luiz Fernando C. de

“…Spectroscopic techniques, including Raman, IR, UV/vis, and NMR were used to characterize the samples of the azo dye Ponceau 4R (also known as E124, New…”
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DFT study of cisplatin@carbon nanohorns complexes by De Souza, Leonardo A., Nogueira, Camila A.S., Lopes, Juliana F., Dos Santos, Hélio F., De Almeida, Wagner B.

“…This paper reports a quantum chemical investigation of the inclusion complex formation between a carbon nanohorn structure and cisplatin molecule, using the…”
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Carotenoids and β-Cyclodextrin Inclusion Complexes: Raman Spectroscopy and Theoretical Investigation by de Oliveira, Vanessa E, Almeida, Eduardo W. C, Castro, Harlem V, Edwards, Howell G. M, Dos Santos, Hélio F, de Oliveira, Luiz Fernando C

“…In the present study, the inclusion processes of β-carotene, astaxanthin, lycopene, and norbixin (NOR) into the β-cyclodextrin (β-CD) cavity were investigated…”
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A SERS investigation of antimicrobial adsorption on silver nanoparticles as mediated by surface modifiers by Filgueiras, Aline Luciano, Dutra, Tailine Mara Freire, Paschoal, Diego, Dos Santos, Hélio F., Sant'Ana, Antonio Carlos

“…In this work, the adsorptions of the antimicrobial drugs aztreonam, tinidazole and metronidazole on silver nanoparticle surfaces were investigated using…”
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