Search Results - "Santos, Hélder A"

Applications of bacterial cellulose in food, cosmetics and drug delivery by Ullah, Hanif, Santos, Hélder A., Khan, Taous

“…Bacterial cellulose (BC) is a versatile biopolymer with better material properties, such as purity, high degree of porosity, relative high permeability to…”
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Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics by Ferro, Cláudio, Florindo, Helena F., Santos, Hélder A.

“…Selenium (Se) is an essential element to human health that can be obtained in nature through several sources. In the human body, it is incorporated into…”
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Polymer-based nanoparticles for oral insulin delivery: Revisited approaches by Fonte, Pedro, Araújo, Francisca, Silva, Cátia, Pereira, Carla, Reis, Salette, Santos, Hélder A., Sarmento, Bruno

“…Diabetes mellitus is a high prevalence and one of the most severe and lethal diseases in the world. Insulin is commonly used to treat diabetes in order to give…”
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Microneedles for painless transdermal immunotherapeutic applications by Amani, Hamed, Shahbazi, Mohammad-Ali, D'Amico, Carmine, Fontana, Flavia, Abbaszadeh, Samin, Santos, Hélder A.

“…Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in the treatment of various diseases. However, owing to the dynamic…”
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The Progress and Prospect of Zeolitic Imidazolate Frameworks in Cancer Therapy, Antibacterial Activity, and Biomineralization by Maleki, Aziz, Shahbazi, Mohammad‐Ali, Alinezhad, Vajiheh, Santos, Hélder A.

“…The progressive development of zeolitic imidazolate frameworks (ZIFs), as a subfamily of metal‐organic frameworks (MOFs), and their unique features, including…”
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Advanced liposome-loaded scaffolds for therapeutic and tissue engineering applications by Cheng, Ruoyu, Liu, Lili, Xiang, Yi, Lu, Yong, Deng, Lianfu, Zhang, Hongbo, Santos, Hélder A., Cui, Wenguo

“…Liposome is one of the most commonly used drug delivery systems in the world, due to its excellent biocompatibility, satisfactory ability in controlling drug…”
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A Versatile and Robust Microfluidic Platform Toward High Throughput Synthesis of Homogeneous Nanoparticles with Tunable Properties by Liu, Dongfei, Cito, Salvatore, Zhang, Yuezhou, Wang, Chang-Fang, Sikanen, Tiina M., Santos, Hélder A.

“…A versatile and robust microfluidic nanoprecipitation platform for high throughput synthesis of nanoparticles is fabricated. The versatility of this platform…”
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Microfluidics for Production of Particles: Mechanism, Methodology, and Applications by Liu, Zehua, Fontana, Flavia, Python, Andre, Hirvonen, Jouni T., Santos, Hélder A.

“…In the past two decades, microfluidics‐based particle production is widely applied for multiple biological usages. Compared to conventional bulk methods,…”
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Production of pure drug nanocrystals and nano co-crystals by confinement methods by Fontana, Flavia, Figueiredo, Patrícia, Zhang, Pei, Hirvonen, Jouni T., Liu, Dongfei, Santos, Hélder A.

“…The use of drug nanocrystals in the drug formulation is increasing due to the large number of poorly water-soluble drug compounds synthetized and due to the…”
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Biomimetic platelet membrane-coated nanoparticles for targeted therapy by Han, Huijie, Bártolo, Raquel, Li, Jiachen, Shahbazi, Mohammad-Ali, Santos, Hélder A.

“…[Display omitted] The development of cell membrane-modified biomimetic nanoparticles has extensively increased during the past years due to their exceptional…”
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Nano‐ and Micro‐Platforms in Therapeutic Proteins Delivery for Cancer Therapy: Materials and Strategies by Han, Huijie, Santos, Hélder A.

“…Proteins have emerged as promising therapeutics in oncology due to their great specificity. Many treatment strategies are developed based on protein biologics,…”
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Preparation of cetyl palmitate-based PEGylated solid lipid nanoparticles by microfluidic technique by Arduino, Ilaria, Liu, Zehua, Rahikkala, Antti, Figueiredo, Patrícia, Correia, Alexandra, Cutrignelli, Annalisa, Denora, Nunzio, Santos, Hélder A.

“…In recent years, several studies have shown that the use of solid lipid nanoparticles (SLN) as a colloidal drug delivery system was more advantageous than…”
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Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications by Tahir, Nayab, Madni, Asadullah, Balasubramanian, Vimalkumar, Rehman, Mubashar, Correia, Alexandra, Kashif, Prince Muhammad, Mäkilä, Ermei, Salonen, Jarno, Santos, Hélder A.

“…[Display omitted] Lipid-polymer hybrid nanoparticles (LPHNPs) are emerging platforms for drug delivery applications. In the present study, methotrexate loaded…”
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The importance of microfluidics for the preparation of nanoparticles as advanced drug delivery systems by Martins, João Pedro, Torrieri, Giulia, Santos, Hélder A

“…Nanoparticles are anticipated to overcome persistent challenges in efficient drug delivery, but the limitations associated with conventional methods of…”
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Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines by Fattahi, Nadia, Shahbazi, Mohammad-Ali, Maleki, Aziz, Hamidi, Mehrdad, Ramazani, Ali, Santos, Hélder A.

“…Many drug molecules that are currently in the market suffer from short half-life, poor absorption, low specificity, rapid degradation, and resistance…”
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Progress in Stimuli‐Responsive Biomaterials for Treating Cardiovascular and Cerebrovascular Diseases by Tapeinos, Christos, Gao, Han, Bauleth‐Ramos, Tomás, Santos, Hélder A.

“…Cardiovascular and cerebrovascular diseases (CCVDs) describe abnormal vascular system conditions affecting the brain and heart. Among these, ischemic heart…”
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Microfluidic fabrication and characterization of Sorafenib-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery by Tahir, Nayab, Madni, Asadullah, Li, Wei, Correia, Alexandra, Khan, Muhammad Muzamil, Rahim, Muhammad Abdur, Santos, Hélder A.

“…[Display omitted] Lipid polymer hybrid nanoparticles (LPHNPs) have been merged as potential nanocarriers for treatment of cancer. In the present study, LPHNPs…”
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Smart Nanoparticle‐Based Platforms for Regulating Tumor Microenvironment and Cancer Immunotherapy by Cheng, Ruoyu, Santos, Hélder A.

“…Tumor development and metastasis are closely related to the tumor microenvironment (TME). Recently, several studies indicate that modulating TME can enhance…”
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Requirements for Animal Experiments: Problems and Challenges by Fontana, Flavia, Figueiredo, Patrícia, Martins, João P., Santos, Hélder A.

“…In vivo models remain a principle screening tool in the drug discovery pipeline. Here, the challenges associated with the need for animal experiments, as well…”
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Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy by Li, Wei, Liu, Dongfei, Zhang, Hongbo, Correia, Alexandra, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Santos, Hélder A.

“…[Display omitted] Harsh conditions of the gastrointestinal tract hinder the oral delivery of many drugs. Developing oral drug delivery systems based on…”
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