Search Results - "Santos, Hélcio Silva Dos"

Casbane diterpene as a promising natural antimicrobial agent against biofilm-associated infections by Carneiro, Victor Alves, Santos, Hélcio Silva Dos, Arruda, Francisco Vassiliepe Sousa, Bandeira, Paulo Nogueira, Albuquerque, Maria Rose Jane Ribeiro, Pereira, Maria Olívia, Henriques, Mariana, Cavada, Benildo Sousa, Teixeira, Edson Holanda

“…Croton nepetaefolius is a native plant from northeastern Brazil that belongs to the Euphorbiaceae family. The biological action of this plant has been…”
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Antifungal and Antioxidant Activities of Vernonia Chalybaea Mart. ex DC. Essential Oil and their Major Constituent β-caryophyllene by Nogueira Sobrinho, Antonio Carlos, Morais, Selene Maia de, Souza, Elnatan Bezerra de, Albuquerque, Maria Rose Jane Ribeiro, Santos, Hélcio Silva dos, Cavalcante, Carolina Sidrim de Paula, Sousa, Halisson Araújo de, Fontenelle, Raquel Oliveira dos Santos

“…This article describes the chemical composition of Vernonia chalybaea essential oil, and investigates its antimicrobial, antioxidant and hemolytic activities…”
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Antibacterial and antibiotic modifying activity, ADMET study and molecular docking of synthetic chalcone (E)-1-(2-hydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps by Rocha, Janaína Esmeraldo, de Freitas, Thiago Sampaio, da Cunha Xavier, Jayze, Pereira, Raimundo Luiz Silva, Junior, Francisco Nascimento Pereira, Nogueira, Carlos Emídio Sampaio, Marinho, Márcia Machado, Bandeira, Paulo Nogueira, de Oliveira, Mateus Rodrigues, Marinho, Emmanuel Silva, Teixeira, Alexandre Magno Rodrigues, dos Santos, Hélcio Silva, Coutinho, Henrique Douglas Melo

“…A large number of infections are caused by multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. Because of that many…”
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Structural, Vibrational and Electrochemical Analysis and Antibacterial Potential of Isomeric Chalcones Derived from Natural Acetophenone by Silva, Priscila Teixeira da, Freitas, Thiago Sampaio de, Sena, Diniz Maciel, Bandeira, Paulo Nogueira, Julião, Murilo Ségio da Silva, Marinho, Emmanuel Silva, Alcanfor, Ana Aline Coêlho, Marinho, Emanuelle Machado, Lima-Neto, Pedro de, Nogueira, Carlos Emídio Sampaio, Coutinho, Henrique Douglas Melo, Leal, Antonio Linkoln Alves Borges, Barreto, Humberto Medeiros, Martins, Natália, Rodrigues Teixeira, Alexandre Magno, Santos, Hélcio Silva dos

“…Background: Chalcones are part of a family of small phenolic compounds that are being extensively studied for presenting a diversity of molecular structures…”
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Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species by Nonato, Carla de Fatima Alves, de Melo, Emerson Vinicius Silva, Camilo, Cicera Janaine, Ferreira, Maria Kueirislene Amâncio, de Meneses, Jane Eire Alencar, da Silva, Antonio Wlisses, Santos, Hélcio Silva Dos, Ribeiro-Filho, Jaime, Paolla Raimundo E Silva, Joanda, Tavares, Josean Fechine, Menezes, Irwin Rose Alencar de, Coutinho, Henrique Douglas Melo, Kowalska, Grażyna, Baj, Tomasz, Kowalski, Radosław, da Costa, José Galberto Martins

“…Species belonging to the genus are used worldwide as foods, beverages, and seasonings. Studies have demonstrated that these species have antioxidant, sedative,…”
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Antibacterial and Antioxidant Activities of Derriobtusone A Isolated from Lonchocarpus obtusus by Pessoa, Otília Deusdênia Loiola, Cavada, Benildo Sousa, Henriques, Mariana, Pereira, Maria Olivia, Teixeira, Edson Holanda, Vasconcelos, Mayron Alves, Bandeira, Paulo Nogueira, dos Santos, Hélcio Silva, Albuquerque, Maria Rose Jane Ribeiro, Arruda, Francisco Vassiliepe Sousa, de Alencar, Daniel Barroso, Saker-Sampaio, Silvana

“…This study evaluated the effect of derriobtusone A, a flavonoid isolated from Lonchocarpus obtusus, on two important pathogenic bacteria, Staphylococcus aureus…”
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Structural characterization, DFT calculations, ADMET studies, antibiotic potentiating activity, evaluation of efflux pump inhibition and molecular docking of chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one by da Cunha Xavier, Jayze, Almeida-Neto, Francisco Wagner de Queiroz, da Silva, Priscila Teixeira, de Sousa, Amanda Pereira, Marinho, Emmanuel Silva, Marinho, Márcia Machado, Rocha, Janaina Esmeraldo, Freitas, Priscila Ramos, de Araújo, Ana Carolina Justino, Freitas, Thiago Santiago, Nogueira, Carlos Emídio Sampaio, de Lima-Neto, Pedro, Bandeira, Paulo Nogueira, Teixeira, Alexandre Magno Rodrigues, Coutinho, Henrique Douglas Melo, dos Santos, Hélcio Silva

“…•A chalcone was synthesized by Claisen-Schmidt condensation reaction.•Structural, electronic and reactivity properties were obtained using DFT.•ADMET studies…”
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Leishmanicidal and healing effects of 3β,6β,16β-trihydroxy lup-20 (29)-ene isolated from Combretum leprosum on Leishmania braziliensis infection in vitro and in vivo by Sombra Santos, Aline, de Castro Rodrigues, Naya Lúcia, Marciano Fonseca, Francisco Rafael, Braga Fayão Oliveira, Nathalia, Oliveira Loucard, Bianca, Fernandes Heredia, Fabíola, Albuquerque Gomes Nogueira, Teresa Neuma, Monteiro Abreu, Ticiana, Silva dos Santos, Hélcio, Holanda Teixeira, Edson, Almeida Moreira Leal, Luzia Kalyne, Brandim Gomes, Regis Bernardo, Romero Teixeira, Clarissa, Teixeira, Maria Jania

“…Treatment of cutaneous leishmaniasis depends on drugs that potentially cause serious side effects and resistance. Thus, topical therapies are attractive…”
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Chemical composition and potentiating action of Norfloxacin mediated by the essential oil of Piper caldense C.D.C. against Staphylococcus aureus strains overexpressing efflux pump genes by Leal, Antonio Linkoln Alves Borges, Bezerra, Camila Fonseca, Confortin, Camila, da Silva, Luiz Everson, Marinho, Emanuelle Machado, Marinho, Márcia Machado, Vasconcelos, Mayron Alves, da Silva, Terezinha Gonçalves, Marinho, Emmanuel Silva, Teixeira, Alexandre Magno Rodrigues, Coutinho, Henrique Douglas Melo, Barreto, Humberto Medeiros, dos Santos, Hélcio Silva

“…Infectious diseases caused by multidrug-resistant microorganisms has increased in the last years. Piper species have been reported as a natural source of…”
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Synthesis, molecular docking, ADMET, and evaluation of the anxiolytic effect in adult zebrafish of synthetic chalcone (E)‐3‐(4‐(dimethylamino)phenyl)‐1‐(2‐hydroxyphenyl)prop‐2‐en‐1‐one: An in vivo and in silico approach by Santos Oliveira, Larissa, Kueirislene Amâncio Ferreira, Maria, Wagner de Queiroz Almeida‐Neto, Francisco, Wlisses da Silva, Antonio, Ivo Lima Pinto Filho, José, Nunes da Rocha, Matheus, Machado Marinho, Emanuelle, Henrique Ferreira Ribeiro, Walber, Machado Marinho, Márcia, Silva Marinho, Emmanuel, Eire Silva Alencar de Menezes, Jane, Santos, Hélcio Silva

“…Background Anxiety disorders represent the complex interaction between biological, psychological, temperamental, and environmental factors; drugs available to…”
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Chemical Composition Determination and Evaluation of the Antimicrobial Activity of Essential Oil from Croton blanchetianus (Euphorbiaceae) against Clinically Relevant Bacteria by Nunes, Aluska Kelly A., Araújo Malveira, Ellen, Lopes Andrade, Alexandre, Barbosa da Silva, Wildson Max, Morais, Selene Maia, Silva dos Santos, Hélcio, Cavalcanti de Albuquerque, Cynthia, Holanda Teixeira, Edson, Nascimento Souza, Diego Nathan, Alves de Vasconcelos, Mayron

“…In this study, the chemical composition of the essential oil (EO) extracted from Croton blanchetianus Baill leaves was identified, and antimicrobial and…”
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Synthesis, spectroscopic characterization, and antibacterial activity of chalcone (2E)‐1‐(3′‐aminophenyl)‐3‐(4‐dimethylaminophenyl)‐prop‐2‐en‐1‐one against multiresistant Staphylococcus aureus carrier of efflux pump mechanisms and β‐lactamase by Silva, Larissa, Donato, Isydório Alves, Bezerra, Suieny Rodrigues, Santos, Hélcio Silva, Bandeira, Paulo Nogueira, Nascimento, Maria Thalia Ramos, Guedes, Jesyka Macêdo, Freitas, Priscila Ramos, Araújo, Ana Carolina Justino, Freitas, Thiago Sampaio, Coutinho, Henrique Douglas Melo, Matos, Yedda Maria Lobo Soares, Oliveira, Lígia Cláudia Castro, Cunha, Francisco Assis Bezerra

“…Background The bacterium Staphylococcus aureus has stood out for presenting a high adaptability, acquiring resistance to multiple drugs. The search for natural…”
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Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg by do Vale, Jean Parcelli Costa, Vasconcelos, Mayron Alves, Arruda, Francisco Vassiliepe Sousa, Firmino, Nairley Cardoso Sá, Pereira, Anna Luísa, Andrade, Alexandre Lopes, Saker-Sampaio, Silvana, Sampaio, Alexandre Holanda, Marinho, Emmanuel Silva, Teixeira, Alexandre Magno Rodrigues, Marinho, Márcia Machado, Rodrigues, Tigressa Helena Soares, Teixeira, Edson Holanda, dos Santos, Hélcio Silva

“…A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths…”
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Neuromodulation of Acid‐Sensitive Ion Channels (ASICs) and Anti‐Inflammatory Potential by Lichenxanthone in Adult Zebrafish (Danio rerio): Experimental and Docking Studies by Ribeiro Liberato, Hortência, Bezerra Maciel, Jéssica, Wlisses Da Silva, Antônio, Eduarda Uchoa Bezerra, Maria, San De Oliveira Brito, Luana, Silva, Jacilene, Kuerislene Amâncio Ferreira, Maria, Machado Marinho, Marcia, Marinho, Gabrielle S, Deusdênia Loiola Pessoa, Otília, Guedes, Maria Izabel F, Goberlânio De Barros Silva, Paulo, Ferreira de Castro Gomes, Andreia, Silva Alencar De Menezes, Jane Eire, Silva Dos Santos, Hélcio

“…The xanthone lichenxanthone did not show toxic effects (LC50>1.0 mg/mL). lichenxanthone prevented nociceptive behavior induced by acidic saline, and its…”
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Chemical composition determination and evaluation of the antibacterial activity of essential oils from Ruellia asperula (Mart. Ex Ness) Lindau and Ruellia paniculata L. against oral streptococci by Vasconcelos, Ariana Azevedo, Veras, Idia Nara de Sousa, Vasconcelos, Mayron Alves de, Andrade, Alexandre Lopes, Dos Santos, Hélcio Silva, Bandeira, Paulo Nogueira, Souza, Elnatan Bezerra de, Albuquerque, Maria Rose Jane Ribeiro, Teixeira, Edson Holanda

“…This study investigated the chemical composition and evaluated the antibacterial and antibiofilm activities of essential oils (EOs) extracted from (EORA) and…”
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Synthesis, antibiotic modifying activity, ADMET study and molecular docking of chalcone (E)-3-(2,4-dichlorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying MepA efflux pumps by Rocha, Janaína Esmeraldo, de Freitas, Thiago Sampaio, da Cunha Xavier, Jayze, Pereira, Raimundo Luiz Silva, Pereira, Francisco Nascimento, Nogueira, Carlos Emídio Sampaio, Marinho, Márcia Machado, Bandeira, Paulo Nogueira, Fernandes, Maria Alyce Albuquerque, Marinho, Emmanuel Silva, Teixeira, Alexandre Magno Rodrigues, dos Santos, Hélcio Silva, Coutinho, Henrique Douglas Melo

“…The Staphylococcus aureus bacteria is a Gram-positive, immobile, non-spore bacterium, with catalase and positive coagulase, among other characteristics. It is…”
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Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one by Hemília de Souza Nunes, Paula, Sampaio de Freitas, Thiago, Esmeraldo Rocha, Janaína, Luiz Silva Pereira, Raimundo, Machado Marinho, Marcia, Oliveira, Mateus Rodrigues, Santos Oliveira, Larissa, Machado Marinho, Emanuelle, Silva Marinho, Emmanuel, Sousa Aquino, Silvia, Emidio Sampaio Nogueira, Carlos, Douglas Melo Coutinho, Henrique, Nogueira Bandeira, Paulo, Magno Rodrigues Teixeira, Alexandre, Santos, Hélcio Silva

“…In recent years, bacterial resistance to traditional drugs has increased, and the need to find new effective antibiotics to treat infections caused by…”
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Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approach by Coutinho, Marnielle Rodrigues, Silva, Antonio Wlisses, Ferreira, Maria Kueirislene Amâncio, Lima Rebouças, Emanuela, Mendes, Francisco Rogênio S., Teixeira, Edson Holanda, Marinho, Emanuelle Machado, Marinho, Márcia Machado, Marinho, Emmanuel Silva, Teixeira, Alexandre Magno Rodrigues, Menezes, Jane Eire Silva Alencar, Santos, Hélcio Silva

“…Drugs used to manage type 2 diabetes mellitus cause adverse effects. Therefore, the search for new drugs as an alternative for the treatment of diabetes…”
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Clove volatile oil-loaded nanoemulsion reduces the anxious-like behavior in adult zebrafish by da Silva Campelo, Matheus, Câmara Neto, João Francisco, de Souza, Álamo Lourenço, Ferreira, Maria Kueirislene Amâncio, dos Santos, Hélcio Silva, Gramosa, Nilce Viana, de Aguiar Soares, Sandra, Ricardo, Nágila Maria Pontes Silva, de Menezes, Jane Eire Silva Alencar, Ribeiro, Maria Elenir Nobre Pinho

“…Background Clove volatile oil (CVO) and its major compound, eugenol (EUG), have anxiolytic effects, but their clinical use has been impaired due to their low…”
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ADMET study and inhibition of Staphylococcus aureus efflux pumps by a synthetic p-aminochalcone by de Sousa, Jonas Nascimento, de Andrade Ferreira Barreto, Júlia, de Alcântara Oliveira, Felipe Araújo, Haydée Lima Ferreira, Josie, Dias Rufino Arcanjo, Daniel, Emidio Sampaio Nogueira, Carlos, Machado Marinho, Márcia, dos Santos, Hélcio Silva, Maria Lins Rolim, Hercília, de Siqueira-Júnior, José Pinto, Douglas Melo Coutinho, Henrique, Medeiros Barreto, Humberto

“…[Display omitted] Bacterial resistance is a global health problem that needs to be solved through discovery of new therapeutic strategies. This study aimed to…”
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