Search Results - "Santos, Fernanda da Costa"
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Quinolones in the Search for New Anticancer Agents
Published in Current pharmaceutical design (01-01-2016)“…Quinolones have a large bio-dynamicity. Although they are well known as antibacterials, another important activity has been investigated - quinolones are able…”
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Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion
Published in Molecules (Basel, Switzerland) (16-11-2022)“…Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical…”
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Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines-From the Synthesis to 3D-Cell Culture Effects
Published in International journal of molecular sciences (12-06-2024)“…Breast cancer stands as one of the foremost cause of cancer-related deaths globally, characterized by its varied molecular subtypes. Each subtype requires a…”
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Chloroquinolone Carboxamide Derivatives as New Anti-HSV-1 Promising Drugs
Published in Current topics in medicinal chemistry (01-01-2023)“…Since the emergence of HSV resistant strains, new antiviral agents have emerged and still are urgently needed, especially those with alternative targets. In…”
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Selective AMPK activator leads to unfolded protein response downregulation and induces breast cancer cell death and autophagy
Published in Life sciences (1973) (01-07-2021)“…AMPK plays a critical role regulating cell metabolism, growth and survival. Interfering with this enzyme activity has been extensively studied as putative…”
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Intra- and intergenomic chromosomal pairing in artificially polyploidized elephant grass and pearl millet hybrids
Published in Pesquisa agropecuaria brasileira (01-09-2017)“…The objective of this work was to evaluate, by genomic in situ hybridization (GISH), pairing configurations as potential indicators of recombination between…”
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1,2:5,6-Di- O -isopropylidene-3- C -methyl-α- D -allofuranose
Published in Acta crystallographica. Section E, Structure reports online (01-10-2013)“…The title carbohydrate, C13H22O6, is a derivative of d-glycose, in which the furanosidic and isopropylidene rings are in twisted conformations. The mean plane…”
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In vitro and in silico DNA interaction studies of a series of 3-carboxamide-4-quinolone derivatives prepared from an one-pot stepwise synthesis (OPSS) method
Published in Journal of molecular structure (05-02-2025)“…•An one-pot stepwise method for synthesizing fifteen 3-carboxamide-4-quinolone derivatives, including compounds with previously reported antitumor…”
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Nucleoside Hydrolase immobilized on magnetic particles as a tool for onflow screening and characterization of inhibitors
Published in Journal of pharmaceutical and biomedical analysis (25-10-2023)“…Nucleoside Hydrolases (NH) are considered a target for the development of new antiprotozoal agents. The development of new and automated screening assays for…”
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Insights into nucleoside hydrolase from Leishmania donovani inhibition: A new bioaffinity chromatography-based screening assay and docking studies
Published in Bioorganic chemistry (01-05-2024)“…[Display omitted] •A new automated assay to screen LdNH based on bioaffinity chromatography is described.•Immobilization of LdNH into silica fused capillaries…”
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Implication of the changing concept of genes on plant breeder's work
Published in Crop breeding and applied biotechnology (01-12-2011)“…The recent genome sequencing of some species has accumulated evidence that for a large number of traits, the control and action of genes are far more complex…”
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Life history of three catfish species (Siluriformes: Ariidae) from southeastern Brazil
Published in Biota neotropica (01-12-2012)“…This study evaluated the spatio-temporal distribution, reproduction and diet of the catfishes Genidens genidens, G. barbus and Aspistor luniscutis in…”
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Propagação vegetativa de porta-enxertos de pereira por estacas semi-lenhosas
Published in Revista Ceres (01-12-2010)“…Pesquisou-se a viabilidade técnica da propagação vegetativa dos porta-enxertos de pereira 'Taiwan Nashi-C', 'Taiwan Mamenashi' (Pyrus calleryana Dcne.) e…”
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Docking of anti-HIV-1 oxoquinoline-acylhydrazone derivatives as potential HSV-1 DNA polymerase inhibitors
Published in Journal of molecular structure (25-09-2014)“…In this work, we use molecular modeling simulations, such as molecular docking, in order to rationalize structural modifications which should increase the…”
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POTENTIAL OF COMMERCIAL MAIZE HYBRIDS TO GENERATE INBRED LINES IN BREEDING PROGRAMS
Published in Pesquisa agropecuária tropical (01-07-2010)“…With the objective of identifying the best commercial hybrids to extract maize lines, a top cross scheme of 49 endogamic partial lines (S3) was carried out…”
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Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies
Published in Current HIV research (01-05-2009)“…We recently described that the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid (compound A)…”
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Propagação vegetativa de porta-enxertos de pereira por estacas semi-lenhosas
Published in Revista Ceres (01-12-2010)“…Pesquisou-se a viabilidade técnica da propagação vegetativa dos porta-enxertos de pereira 'Taiwan Nashi-C', 'Taiwan Mamenashi' (Pyrus calleryana Dcne.) e…”
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POTENCIAL DE HÍBRIDOS COMERCIAIS DE MILHO PARA OBTENÇÃO DE LINHAGENS EM PROGRAMAS DE MELHORAMENTO
Published in Pesquisa agropecuária tropical (16-08-2010)Get full text
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POTENTIAL OF COMMERCIAL MAIZE HYBRIDS TO GENERATE INBRED LINES IN BREEDING PROGRAMS POTENCIAL DE HÍBRIDOS COMERCIAIS DE MILHO PARA OBTENÇÃO DE LINHAGENS EM PROGRAMAS DE MELHORAMENTO
Published in Pesquisa agropecuária tropical (01-08-2010)“…With the objective of identifying the best commercial hybrids to extract maize lines, a top cross scheme of 49 endogamic partial lines (S 3 ) was carried out…”
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20
1,2:5,6-Di-O-iso-propyl-idene-3-C-methyl-α-d-allo-furan-ose
Published in Acta crystallographica. Section E, Structure reports online (2013)“…The title carbohydrate, C13H22O6, is a derivative of d-glycose, in which the furan-osidic and iso-propyl-idene rings are in twisted conformations. The mean…”
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