Search Results - "Santos, Fábio M. F."
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Circularly Polarized Luminescence of Boronic Acid-Derived Salicylidenehydrazone Complexes Containing Chiral Boron as Stereogenic Unit
Published in Journal of organic chemistry (16-11-2018)“…Racemic mixtures of boronic acid-derived salicylidenehydrazone (BASHY) complexes were enantiomerically resolved. The chiroptical properties of the…”
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2
BASHY Dyes Are Highly Efficient Lipid Droplet-Targeting Photosensitizers that Induce Ferroptosis through Lipid Peroxidation
Published in Bioconjugate chemistry (20-12-2023)“…Ferroptosis is an iron-dependent lipid-peroxidation-driven mechanism of cell death and a promising therapeutic target to eradicate cancer cells. In this study,…”
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3
Modular Assembly of Reversible Multivalent Cancer‐Cell‐Targeting Drug Conjugates
Published in Angewandte Chemie International Edition (01-08-2017)“…Herein is described a new modular platform for the construction of cancer‐cell‐targeting drug conjugates. Tripodal boronate complexes featuring reversible…”
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4
Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells
Published in Chemical communications (Cambridge, England) (2017)“…Fluorophores are indispensable for imaging biological processes. We report the design and synthesis of azide-tagged boronic acid salicylidenehydrazone (BASHY)…”
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A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes)
Published in Chemistry : a European journal (26-01-2016)“…The modular assembly of boronic acids with Schiff‐base ligands enabled the construction of innovative fluorescent dyes [boronic acid salicylidenehydrazone…”
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6
The BASHY Platform Enables the Assembly of a Fluorescent Bortezomib–GV1001 Conjugate
Published in ACS medicinal chemistry letters (13-01-2022)“…In this study, we show that fluorescent boronic-acid derived salicylidenehydrazone complexes (BASHY) can function as fluorescent linkers for bioconjugates that…”
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BASHY Dye Platform Enables the Fluorescence Bioimaging of Myelin Debris Phagocytosis by Microglia during Demyelination
Published in Cells (Basel, Switzerland) (13-11-2021)“…Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is characterized by the presence of demyelinated regions with accumulated…”
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N‑Heterocyclic Carbene Catalyzed Addition of Aldehydes to Diazo Compounds: Stereoselective Synthesis of N‑Acylhydrazones
Published in Organic letters (05-04-2013)“…An innovative stereoselective synthesis of N-acylhydrazones via an unprecedented N-heterocyclic carbene catalyzed addition of aldehydes to diazo compounds is…”
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9
A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes)
Published in Chemistry : a European journal (26-01-2016)“…The modular assembly of boronic acids with Schiff-base ligands enabled the construction of innovative fluorescent dyes [boronic acid salicylidenehydrazone…”
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Cyanine‐Like Boronic Acid‐Derived Salicylidenehydrazone Complexes (Cy‐BASHY) for Bioimaging Applications
Published in Chemistry : a European journal (06-11-2020)“…Boronic acid‐derived salicylidenehydrazone complex (BASHY) dyes with a polymethine backbone were designed to yield efficient red‐emitting and two‐photon…”
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11
Polyoxazoline‐Based Nanovaccine Synergizes with Tumor‐Associated Macrophage Targeting and Anti‐PD‐1 Immunotherapy against Solid Tumors
Published in Advanced science (01-09-2023)“…Immune checkpoint blockade reaches remarkable clinical responses. However, even in the most favorable cases, half of these patients do not benefit from these…”
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A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes)
Published in Chemistry : a European journal (26-01-2016)“…Invited for the cover of this issue are Uwe Pischel, Pedro Gois and co‐workers at the Universities of Huelva and Lisbon. The image depicts a puzzle, which…”
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13
Electronic and Functional Scope of Boronic Acid Derived Salicylidenehydrazone (BASHY) Complexes as Fluorescent Dyes
Published in Journal of organic chemistry (21-07-2017)“…A series of boronic acid derived salicylidenehydrazone (BASHY) complexes was prepared and photophysically characterized. The dye platform can be modified by…”
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Cover Picture: A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes) (Chem. Eur. J. 5/2016)
Published in Chemistry : a European journal (26-01-2016)“…A multicomponent reaction, symbolized on the cover by a puzzle, was used to prepare a molecularly diverse series of boron‐containing heterocyclic dyes [boronic…”
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15
Modular Assembly of Reversible Multivalent Cancer‐Cell‐Targeting Drug Conjugates
Published in Angewandte Chemie (01-08-2017)“…Herein is described a new modular platform for the construction of cancer‐cell‐targeting drug conjugates. Tripodal boronate complexes featuring reversible…”
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16
Engineering the BASHY Dye Platform toward Architectures with Responsive Fluorescence
Published in Chemistry : a European journal (02-06-2023)“…A set of nine boronic‐acid‐derived salicylidenehydrazone (BASHY) complexes has been synthesized in good to very good chemical yields in a versatile…”
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17
Exploring the reactivity of (hetero)aryl amides in the Chan‐Evans‐Lam reaction with arylalkenyl boron reagents
Published in European journal of organic chemistry (18-11-2024)“…The unique reactivity and stability of enamides make them attractive reagents in organic synthesis. Herein, we investigated the reactivity of acetanilides and…”
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Highly Efficient Energy Transfer Cassettes by Assembly of Boronic Acid Derived Salicylidenehydrazone Complexes
Published in ChemPhotoChem (01-12-2018)“…Energy transfer cassettes that build on the platform of boronic acid derived salicylidenehydrazone (BASHY) complexes were prepared. The functional flexibility…”
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Cover Feature: Cyanine‐Like Boronic Acid‐Derived Salicylidenehydrazone Complexes (Cy‐BASHY) for Bioimaging Applications (Chem. Eur. J. 62/2020)
Published in Chemistry : a European journal (06-11-2020)“…Boronic acid derived salicylidenehydrazone (Bashy) complexes can be designed as bright fluorescent dyes with tunable emission in the red spectral window. The…”
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Cover Feature: Engineering the BASHY Dye Platform toward Architectures with Responsive Fluorescence (Chem. Eur. J. 31/2023)
Published in Chemistry : a European journal (02-06-2023)“…BASHY dyes, such as the one drawn in the foreground, are prepared in a multicomponent reaction. This is symbolized by the background, which shows part of a…”
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