Search Results - "Santos, Everton O. L."
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Flavonols modulate the effector functions of healthy individuals' immune complex-stimulated neutrophils: A therapeutic perspective for rheumatoid arthritis
Published in International immunopharmacology (01-07-2014)“…Rheumatoid arthritis (RA) patients usually exhibit immune complex (IC) deposition and increased neutrophil activation in the joint. In this study, we assessed…”
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Optimization of a flow cytometric assay to evaluate the human neutrophil ability to phagocytose immune complexes via Fcγ and complement receptors
Published in Journal of pharmacological and toxicological methods (01-03-2015)“…This study aims to optimize some experimental conditions of a flow cytometric assay to examine the human neutrophil ability to phagocytose immune complexes…”
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The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3′,4′-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps
Published in Free radical biology & medicine (01-02-2018)“…In this study, we report the ability of a set of eight 3-phenylcoumarin derivatives bearing 6,7- or 5,7-dihydroxyl groups, free or acetylated, bound to the…”
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Baccharis dracunculifolia DC (Asteraceae) selectively modulates the effector functions of human neutrophils
Published in Journal of pharmacy and pharmacology (01-12-2017)“…Objectives To examine whether the hydroalcoholic extract from Baccharis dracunculifolia leaves (BdE) modulates the human neutrophil oxidative metabolism,…”
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7-Hydroxycoumarin modulates the oxidative metabolism, degranulation and microbial killing of human neutrophils
Published in Chemico-biological interactions (25-10-2013)“…•7-Hydroxycoumarin derivatives modulate the oxidative metabolism of human neutrophils.•7-Hydroxycoumarin impairs degranulation of neutrophils and killing of…”
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The Flavonols Quercetin, Myricetin, Kaempferol, and Galangin Inhibit the Net Oxygen Consumption by Immune Complex- Stimulated Human and Rabbit Neutrophils
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-07-2014)“…Stimulated human neutrophils exhibit increased net oxygen consumption (NOC) due to the conversion of O into the superoxide anion by the NADPH oxidase enzymatic…”
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3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils
Published in International immunopharmacology (01-02-2013)“…Immune complex (IC) deposition in tissues triggers the release of harmful oxidant and lytic compounds by neutrophils. We examined how ten 3-phenylcoumarin…”
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Baccharis dracunculifoliaDC (Asteraceae) selectively modulates the effector functions of human neutrophils
Published in Journal of pharmacy and pharmacology (01-12-2017)“…Objectives To examine whether the hydroalcoholic extract from Baccharis dracunculifolia leaves (BdE) modulates the human neutrophil oxidative metabolism,…”
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Journal Article -
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The flavonoid galangin induces release of neutrophil extracellular traps and enhances resolution of E. coli pneumonia
Published in The Journal of immunology (1950) (01-05-2017)“…Killing of invading bacteria is essential for efficient control of infection and return to homeostasis. Phagocytosis of E. coli by neutrophils induces…”
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